PD-L1 expression in the Merkel cell carcinoma microenvironment: association with inflammation, Merkel cell polyomavirus, and overall survival EJ Lipson, JG Vincent, M Loyo, LT Kagohara, BS Luber, H Wang, H Xu, ... Cancer immunology research 1 (1), 54-63, 2013 | 426 | 2013 |
The TGFβ–miR200–MIG6 pathway orchestrates the EMT-associated kinase switch that induces resistance to EGFR inhibitors E Izumchenko, X Chang, C Michailidi, L Kagohara, R Ravi, K Paz, M Brait, ... Cancer research 74 (14), 3995-4005, 2014 | 150 | 2014 |
Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA E Izumchenko, X Chang, M Brait, E Fertig, LT Kagohara, A Bedi, ... Nature communications 6 (1), 8258, 2015 | 149 | 2015 |
Epigenetic regulation of gene expression in cancer: techniques, resources and analysis LT Kagohara, GL Stein-O’Brien, D Kelley, E Flam, HC Wick, LV Danilova, ... Briefings in functional genomics 17 (1), 49-63, 2018 | 122 | 2018 |
Phosphorylation-induced conformational dynamics in an intrinsically disordered protein and potential role in phenotypic heterogeneity P Kulkarni, MK Jolly, D Jia, SM Mooney, A Bhargava, LT Kagohara, ... Proceedings of the National Academy of Sciences 114 (13), E2644-E2653, 2017 | 81 | 2017 |
From bench to bedside: Single-cell analysis for cancer immunotherapy EF Davis-Marcisak, A Deshpande, GL Stein-O’Brien, WJ Ho, D Laheru, ... Cancer cell 39 (8), 1062-1080, 2021 | 78 | 2021 |
Integrated single-cell and bulk gene expression and ATAC-seq reveals heterogeneity and early changes in pathways associated with resistance to cetuximab in HNSCC-sensitive cell … LT Kagohara, F Zamuner, EF Davis-Marcisak, G Sharma, M Considine, ... British journal of cancer 123 (1), 101-113, 2020 | 45 | 2020 |
Integrated time course omics analysis distinguishes immediate therapeutic response from acquired resistance G Stein-O’Brien, LT Kagohara, S Li, M Thakar, R Ranaweera, H Ozawa, ... Genome medicine 10, 1-22, 2018 | 36 | 2018 |
Global and gene-specific DNA methylation pattern discriminates cholecystitis from gallbladder cancer patients in Chile LT Kagohara, JL Schussel, T Subbannayya, N Sahasrabuddhe, C Lebron, ... Future oncology 11 (2), 233-249, 2015 | 30 | 2015 |
Entinostat Decreases Immune Suppression to Promote Antitumor Responses in a HER2+ Breast Tumor Microenvironment DN Sidiropoulos, CI Rafie, JK Jang, S Castanon, AG Baugh, E Gonzalez, ... Cancer immunology research 10 (5), 656-669, 2022 | 29 | 2022 |
Extracellular vesicles released by tumor endothelial cells spread immunosuppressive and transforming signals through various recipient cells T Lopatina, E Favaro, L Danilova, EJ Fertig, AV Favorov, LT Kagohara, ... Frontiers in Cell and Developmental Biology 8, 698, 2020 | 22 | 2020 |
KRAS mutation status is highly homogeneous between areas of the primary tumor and the corresponding metastasis of colorectal adenocarcinomas: one less problem in patient care MP De Macedo, FM Melo, HSC Ribeiro, MC Marques, LT Kagohara, ... American journal of cancer research 7 (9), 1978, 2017 | 22 | 2017 |
Epigenetic inactivation of VGF associated with Urothelial Cell Carcinoma and its potential as a non-invasive biomarker using urine M Hayashi, H Bernert, LT Kagohara, L Maldonado, M Brait, ... Oncotarget 5 (10), 3350, 2014 | 22 | 2014 |
Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence S Zhang, L Yuan, L Danilova, G Mo, Q Zhu, A Deshpande, ATF Bell, ... Genome medicine 15 (1), 72, 2023 | 20 | 2023 |
Profiling of syngeneic mouse HCC tumor models as a framework to understand anti–PD‐1 sensitive tumor microenvironments DJ Zabransky, L Danilova, JM Leatherman, TY Lopez‐Vidal, J Sanchez, ... Hepatology 77 (5), 1566-1579, 2023 | 20 | 2023 |
CoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network EJ Fertig, H Ozawa, M Thakar, JD Howard, LT Kagohara, G Krigsfeld, ... Oncotarget 7 (45), 73845, 2016 | 20 | 2016 |
Uncovering the spatial landscape of molecular interactions within the tumor microenvironment through latent spaces A Deshpande, M Loth, DN Sidiropoulos, S Zhang, L Yuan, ATF Bell, ... Cell systems 14 (4), 285-301. e4, 2023 | 14 | 2023 |
Splice Expression Variation Analysis (SEVA) for inter-tumor heterogeneity of gene isoform usage in cancer B Afsari, T Guo, M Considine, L Florea, LT Kagohara, GL Stein-O’Brien, ... Bioinformatics 34 (11), 1859-1867, 2018 | 13 | 2018 |
Implantation of a neoantigen-targeted hydrogel vaccine prevents recurrence of pancreatic adenocarcinoma after incomplete resection D Delitto, DJ Zabransky, F Chen, ED Thompson, JW Zimmerman, ... Oncoimmunology 10 (1), 2001159, 2021 | 12 | 2021 |
Comparative mutational landscape analysis of patient-derived tumour xenografts M Brait, E Izumchenko, LT Kagohara, S Long, PT Wysocki, B Faherty, ... British journal of cancer 116 (4), 515-523, 2017 | 12 | 2017 |