A reciprocal repression between ZEB1 and members of the miR‐200 family promotes EMT and invasion in cancer cells U Burk, J Schubert, U Wellner, O Schmalhofer, E Vincan, S Spaderna, ... EMBO reports 9 (6), 582-589, 2008 | 2057 | 2008 |
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs U Wellner, J Schubert, UC Burk, O Schmalhofer, F Zhu, A Sonntag, ... Nature cell biology 11 (12), 1487-1495, 2009 | 1948 | 2009 |
EMT in cancer T Brabletz, R Kalluri, MA Nieto, RA Weinberg Nature Reviews Cancer 18 (2), 128-134, 2018 | 1922 | 2018 |
Migrating cancer stem cells—an integrated concept of malignant tumour progression T Brabletz, A Jung, S Spaderna, F Hlubek, T Kirchner Nature Reviews Cancer 5 (9), 744-749, 2005 | 1742 | 2005 |
Guidelines and definitions for research on epithelial–mesenchymal transition J Yang, P Antin, G Berx, C Blanpain, T Brabletz, M Bronner, K Campbell, ... Nature reviews Molecular cell biology 21 (6), 341-352, 2020 | 1599 | 2020 |
Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment T Brabletz, A Jung, S Reu, M Porzner, F Hlubek, LA Kunz-Schughart, ... Proceedings of the National Academy of Sciences 98 (18), 10356-10361, 2001 | 1418 | 2001 |
Oncogenic roles of EMT-inducing transcription factors A Puisieux, T Brabletz, J Caramel Nature cell biology 16 (6), 488-494, 2014 | 1112 | 2014 |
Wnt/β-catenin signaling in cancer stemness and malignant behavior R Fodde, T Brabletz Current opinion in cell biology 19 (2), 150-158, 2007 | 1010 | 2007 |
E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer O Schmalhofer, S Brabletz, T Brabletz Cancer and Metastasis Reviews 28, 151-166, 2009 | 969 | 2009 |
The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer AM Krebs, J Mitschke, M Lasierra Losada, O Schmalhofer, M Boerries, ... Nature cell biology 19 (5), 518-529, 2017 | 943 | 2017 |
The ZEB/miR‐200 feedback loop—a motor of cellular plasticity in development and cancer? S Brabletz, T Brabletz EMBO reports 11 (9), 670-677, 2010 | 918 | 2010 |
β-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer T Brabletz, A Jung, S Dag, F Hlubek, T Kirchner The American journal of pathology 155 (4), 1033-1038, 1999 | 901 | 1999 |
The transcription factor ZEB1 (δEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity K Aigner, B Dampier, L Descovich, M Mikula, A Sultan, M Schreiber, ... Oncogene 26 (49), 6979-6988, 2007 | 762 | 2007 |
Wnt signalling induces maturation of Paneth cells in intestinal crypts JH van Es, P Jay, A Gregorieff, ME van Gijn, S Jonkheer, P Hatzis, ... Nature cell biology 7 (4), 381-386, 2005 | 757 | 2005 |
Invasion and metastasis in colorectal cancer: epithelial-mesenchymal transition, mesenchymal-epithelial transition, stem cells and β-catenin T Brabletz, F Hlubek, S Spaderna, O Schmalhofer, E Hiendlmeyer, A Jung, ... Cells tissues organs 179 (1-2), 56-65, 2005 | 709 | 2005 |
To differentiate or not—routes towards metastasis T Brabletz Nature Reviews Cancer 12 (6), 425-436, 2012 | 705 | 2012 |
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer S Spaderna, O Schmalhofer, M Wahlbuhl, A Dimmler, K Bauer, A Sultan, ... Cancer research 68 (2), 537-544, 2008 | 681 | 2008 |
A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer S Spaderna, O Schmalhofer, F Hlubek, G Berx, A Eger, S Merkel, A Jung, ... Gastroenterology 131 (3), 830-840, 2006 | 570 | 2006 |
Non-redundant functions of EMT transcription factors MP Stemmler, RL Eccles, S Brabletz, T Brabletz Nature cell biology 21 (1), 102-112, 2019 | 512 | 2019 |
EMT and MET in metastasis: where are the cancer stem cells? T Brabletz Cancer cell 22 (6), 699-701, 2012 | 504 | 2012 |