Stephen E. Miller
Stephen E. Miller
Principal Scientist, Group Leader, Genentech
Verified email at
Cited by
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An intrinsically disordered peptide facilitates non‐endosomal cell entry
SH Medina, SE Miller, AI Keim, AP Gorka, MJ Schnermann, JP Schneider
Angewandte Chemie 128 (10), 3430-3433, 2016
Evaluation of triazolamers as active site inhibitors of HIV-1 protease
AL Jochim, SE Miller, NG Angelo, PS Arora
Bioorganic & medicinal chemistry letters 19 (21), 6023-6026, 2009
Effects of side chains in helix nucleation differ from helix propagation
SE Miller, AM Watkins, NR Kallenbach, PS Arora
Proceedings of the National Academy of Sciences 111 (18), 6636-6641, 2014
Fluorous phase‐directed peptide assembly affords Nano‐Peptisomes capable of ultrasound‐triggered cellular delivery
SH Medina, MS Michie, SE Miller, MJ Schnermann, JP Schneider
Angewandte Chemie 129 (38), 11562-11566, 2017
Reversible α-helix formation controlled by a hydrogen bond surrogate
SE Miller, NR Kallenbach, PS Arora
Tetrahedron 68 (23), 4434-4437, 2012
Electrostatically driven guanidinium interaction domains that control hydrogel-mediated protein delivery in vivo
SE Miller, Y Yamada, N Patel, E Suárez, C Andrews, S Tau, BT Luke, ...
ACS Central Science 5 (11), 1750-1759, 2019
Synthesis of Hydrogen‐Bond Surrogate α‐Helices as Inhibitors of Protein‐Protein Interactions
SE Miller, PF Thomson, PS Arora
Current protocols in chemical biology 6 (2), 101-116, 2014
Uncoupling the folding-function paradigm of lytic peptides to deliver impermeable inhibitors of intracellular protein–protein interactions
SE Miller, K Tsuji, RPM Abrams, TR Burke Jr, JP Schneider
Journal of the American Chemical Society 142 (47), 19950-19955, 2020
Dynamic protein folding at the surface of stimuli‐responsive peptide fibrils
RP Nagarkar, SE Miller, S Zhong, DJ Pochan, JP Schneider
Protein Science 27 (7), 1243-1251, 2018
Rational design strategies for developing synthetic inhibitors of helical protein interfaces
AB Mahon, SE Miller, ST Joy, PS Arora
Protein-protein interactions, 197-230, 2012
The effect of turn residues on the folding and cell‐penetrating activity of β‐hairpin peptides and applications toward protein delivery
SE Miller, JP Schneider
Peptide Science 112 (1), e24125, 2020
Potent and selective binders of the E3 ubiquitin ligase ZNRF3 stimulate Wnt signaling and intestinal organoid growth
YT Kschonsak, X Gao, SE Miller, S Hwang, H Marei, P Wu, Y Li, K Ruiz, ...
Cell Chemical Biology, 2024
Synthetic Multivalent Disulfide-Constrained Peptide Agonists Potentiate Wnt1/β-Catenin Signaling via LRP6 Coreceptor Clustering
AK Thakur, SE Miller, NPD Liau, S Hwang, S Hansen, F de Sousa e Melo, ...
ACS Chemical Biology 18 (4), 772-784, 2023
Reversibly crosslinked helical hydrogen bond surrogate macrocycles
PS Arora, SE Miller
US Patent App. 14/380,708, 2015
Bioproduction Platform to Generate Functionalized Disulfide-Constrained Peptide Analogues
S Hwang, AT Balana, B Martin, M Clarkson, P Di Lello, H Wu, Y Li, ...
ACS Bio & Med Chem Au, 2024
Abstract 1324 A disulfide constrained peptide platform to identify ZNRF3 antagonists for Wnt signaling activation
X Gao, Y Kschonsak, S Miller, P Wu, S Hwang, Y Li, S Harris, ...
Journal of Biological Chemistry 300 (3), 2024
Peptide hydrogels and use thereof
J Schneider, S Walsh, S Miller, Y Yamada, S Durum, C Andrews, W Li, ...
US Patent 11,661,439, 2023
Peptide hydrogels and use thereof
J Schneider, S Walsh, S Miller, Y Yamada, S Durum, S Andrews, W Li, J Hixon ...
WO Patent WO 2019/117976 A1, 2019
Anhydrous Monoalkylguanidines in Aprotic and Nonpolar Solvents: Models for Deprotonated Arginine Side Chains in Membrane Environments
AT Banyikwa, SE Miller, RA Krebs, Y Xiao, JM Carney, MS Braiman
ACS omega 2 (10), 7239-7252, 2017
Using α-helices with dynamic constraints to probe peptide folding and protein-protein interactions.
SE Miller
New York University, 2014
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