Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists L Turski, K Bressler, K Jürgen Rettig, PA Löschmann, H Wachtel Nature 349 (6308), 414-418, 1991 | 684 | 1991 |
The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis N Sommer, PA Löschmann, GH Northoff, M Weller, A Steinbrecher, ... Nature medicine 1 (3), 244-248, 1995 | 438 | 1995 |
Induction of nitric oxide synthase and nitric oxide‐mediated apoptosis in neuronal PC12 cells after stimulation with tumor necrosis factor‐α/lipopolysaccharide MT Heneka, PA Löschmann, M Gleichmann, M Weller, JB Schulz, ... Journal of neurochemistry 71 (1), 88-94, 1998 | 264 | 1998 |
Targeting neuroinflammation to treat Alzheimer’s disease A Ardura-Fabregat, E Boddeke, A Boza-Serrano, S Brioschi, ... CNS drugs 31, 1057-1082, 2017 | 260 | 2017 |
Glutathione depletion and neuronal cell death: the role of reactive oxygen intermediates and mitochondrial function U Wüllner, J Seyfried, P Groscurth, S Beinroth, S Winter, M Gleichmann, ... Brain research 826 (1), 53-62, 1999 | 238 | 1999 |
Glutathione depletion potentiates MPTP and MPP+ toxicity in nigral dopaminergic neurones U Wüllner, PA Löschmann, JB Schulz, A Schmid, R Dringen, F Eblen, ... Neuroreport 7 (4), 921-923, 1996 | 211 | 1996 |
Decorin gene transfer-mediated suppression of TGF-β synthesis abrogates experimental malignant glioma growth in vivo M Ständer, U Naumann, L Dumitrescu, M Heneka, P Löschmann, ... Gene Therapy 5 (9), 1187-1194, 1998 | 171 | 1998 |
Synergism of the AMPA-antagonist NBQX and the NMDA-antagonist CPP with L-dopa in models of Parkinson's disease PA Löschmann, KW Lange, M Kunow, KJ Rettig, P Jähnig, T Honore, ... Journal of neural transmission-Parkinson's disease and dementia section 3 …, 1991 | 163 | 1991 |
Cooperative interception of neuronal apoptosis by BCL‐2 and BAG‐1 expression: prevention of caspase activation and reduced production of reactive oxygen species JB Schulz, D Bremen, JC Reed, J Lommatzsch, S Takayama, U Wüllner, ... Journal of neurochemistry 69 (5), 2075-2086, 1997 | 145 | 1997 |
Extended therapeutic window for caspase inhibition and synergy with MK-801 in the treatment of cerebral histotoxic hypoxia. JÈB Schulz, M Weller, RT Matthews, MT Heneka, P Groscurth, ... Cell Death & Differentiation 5 (10), 1998 | 134 | 1998 |
Cell death and apoptosis regulating proteins in Parkinson’s disease–a cautionary note U Wüllner, J Kornhuber, M Weller, JB Schulz, PA Löschmann, P Riederer, ... Acta neuropathologica 97, 408-412, 1999 | 129 | 1999 |
Antiparkinsonian activity of Ro 25-6981, a NR2B subunit specific NMDA receptor antagonist, in animal models of Parkinson's disease PA Löschmann, C De Groote, L Smith, U Wüllner, G Fischer, JA Kemp, ... Experimental neurology 187 (1), 86-93, 2004 | 117 | 2004 |
The competitive NMDA antagonist CPP protects substantia nigra neurons from MPTP-induced degeneration in primates KW Lange, PA Löschmann, E Sofic, M Burg, R Horowski, KT Kalveram, ... Naunyn-Schmiedeberg's archives of pharmacology 348, 586-592, 1993 | 108 | 1993 |
Therapeutic potential of phosphodiesterase type 4 inhibition in chronic autoimmune demyelinating disease N Sommer, R Martin, HF McFarland, L Quigley, B Cannella, CS Raine, ... Journal of neuroimmunology 79 (1), 54-61, 1997 | 101 | 1997 |
Apoptotic cell death in the cerebellum of mutant weaver and lurcher mice U Wüllner, PA Löschmann, M Weller, T Klockgether Neuroscience letters 200 (2), 109-112, 1995 | 99 | 1995 |
The NMDA antagonist memantine impairs classical eyeblink conditioning in humans MM Schugens, R Egerter, I Daum, K Schepelmann, T Klockgether, ... Neuroscience Letters 224 (1), 57-60, 1997 | 93 | 1997 |
Do NMDA receptor antagonists protect against MPTP-toxicity? Biochemical and immunocytochemical analyses in black mice A Kupsch, PA Löschmann, H Sauer, G Arnold, P Renner, D Pufal, M Burg, ... Brain research 592 (1-2), 74-83, 1992 | 92 | 1992 |
Kainate microinjection into the dorsal raphe nucleus induces 5-HT release in the amygdala and periaqueductal gray MB Viana, FG Graeff, PA Löschmann Pharmacology Biochemistry and Behavior 58 (1), 167-172, 1997 | 81 | 1997 |
Polymerized hemoglobin restores cardiovascular and kidney function in endotoxin-induced shock in the rat. MT Heneka, PA Löschmann, H Osswald The Journal of clinical investigation 99 (1), 47-54, 1997 | 74 | 1997 |
The antiparkinsonian agent budipine is an N-methyl-D-aspartate antagonist T Klockgether, P Jacobsen, PA Löschmann, L Turski Journal of neural transmission-Parkinson's disease and dementia section 5 …, 1993 | 63 | 1993 |