| Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence RM Kortlever, PJ Higgins, R Bernards Nature cell biology 8 (8), 877-884, 2006 | 695 | 2006 |
| Myc cooperates with Ras by programming inflammation and immune suppression RM Kortlever, NM Sodir, CH Wilson, DL Burkhart, L Pellegrinet, ... Cell 171 (6), 1301-1315. e14, 2017 | 466 | 2017 |
| Selective activation of p53-mediated tumour suppression in high-grade tumours MR Junttila, AN Karnezis, D Garcia, F Madriles, RM Kortlever, F Rostker, ... Nature 468 (7323), 567-571, 2010 | 273 | 2010 |
| TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence TR Brummelkamp, RM Kortlever, M Lingbeek, F Trettel, ME MacDonald, ... Journal of Biological Chemistry 277 (8), 6567-6572, 2002 | 208 | 2002 |
| MYC instructs and maintains pancreatic adenocarcinoma phenotype NM Sodir, RM Kortlever, VJA Barthet, T Campos, L Pellegrinet, S Kupczak, ... Cancer discovery 10 (4), 588-607, 2020 | 143 | 2020 |
| A MYC-driven change in mitochondrial dynamics limits YAP/TAZ function in mammary epithelial cells and breast cancer B von Eyss, LA Jaenicke, RM Kortlever, N Royla, KE Wiese, S Letschert, ... Cancer cell 28 (6), 743-757, 2015 | 139 | 2015 |
| Senescence, wound healing, and cancer: the PAI-1 connection RM Kortlever, R Bernards Cell cycle 5 (23), 2697-2703, 2006 | 109 | 2006 |
| Modeling pharmacological inhibition of mast cell degranulation as a therapy for insulinoma L Soucek, JJ Buggy, R Kortlever, S Adimoolam, HA Monclús, ... Neoplasia 13 (11), 1093-IN43, 2011 | 67 | 2011 |
| Transforming growth factor-β requires its target plasminogen activator inhibitor-1 for cytostatic activity RM Kortlever, JH Nijwening, R Bernards Journal of Biological Chemistry 283 (36), 24308-24313, 2008 | 62 | 2008 |
| The role of the pseudoknot at the 3'end of turnip yellow mosaic virus RNA in minus-strand synthesis by the viral RNA-dependent RNA polymerase BA Deiman, RM Kortlever, CW Pleij Journal of virology 71 (8), 5990-5996, 1997 | 58 | 1997 |
| Suppression of the p53-dependent replicative senescence response by lysophosphatidic acid signaling RM Kortlever, TR Brummelkamp, LA van Meeteren, WH Moolenaar, ... Molecular Cancer Research 6 (9), 1452-1460, 2008 | 31 | 2008 |
| Heterogeneity of Myc expression in breast cancer exposes pharmacological vulnerabilities revealed through executable mechanistic modeling P Kreuzaler, MA Clarke, EJ Brown, CH Wilson, RM Kortlever, N Piterman, ... Proceedings of the National Academy of Sciences 116 (44), 22399-22408, 2019 | 18 | 2019 |
