Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA L Warren, PD Manos, T Ahfeldt, YH Loh, H Li, F Lau, W Ebina, PK Mandal, ... Cell stem cell 7 (5), 618-630, 2010 | 3378 | 2010 |
Differential methylation of tissue-and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts A Doi, IH Park, B Wen, P Murakami, MJ Aryee, R Irizarry, B Herb, ... Nature genetics 41 (12), 1350-1353, 2009 | 1396 | 2009 |
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells S Loewer, MN Cabili, M Guttman, YH Loh, K Thomas, IH Park, M Garber, ... Nature genetics 42 (12), 1113-1117, 2010 | 1079 | 2010 |
Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells EM Chan, S Ratanasirintrawoot, IH Park, PD Manos, YH Loh, H Huo, ... Nature biotechnology 27 (11), 1033-1037, 2009 | 679 | 2009 |
Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice TM Schlaeger, S Bartunkova, JA Lawitts, G Teichmann, W Risau, ... Proceedings of the National Academy of Sciences 94 (7), 3058-3063, 1997 | 576 | 1997 |
A comparison of non-integrating reprogramming methods TM Schlaeger, L Daheron, TR Brickler, S Entwisle, K Chan, A Cianci, ... Nature biotechnology 33 (1), 58-63, 2015 | 562 | 2015 |
Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene HKA Mikkola, J Klintman, H Yang, H Hock, TM Schlaeger, Y Fujiwara, ... Nature 421 (6922), 547-551, 2003 | 474 | 2003 |
Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo HKA Mikkola, Y Fujiwara, TM Schlaeger, D Traver, SH Orkin Blood, The Journal of the American Society of Hematology 101 (2), 508-516, 2003 | 434 | 2003 |
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells FG Lafaille, IM Pessach, SY Zhang, MJ Ciancanelli, M Herman, ... Nature 491 (7426), 769-773, 2012 | 351 | 2012 |
Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models W Goessling, RS Allen, X Guan, P Jin, N Uchida, M Dovey, JM Harris, ... Cell stem cell 8 (4), 445-458, 2011 | 331 | 2011 |
Vascular endothelial cell lineage-specific promoter in transgenic mice TM Schlaeger, Y Qin, Y Fujiwara, J Magram, TN Sato Development 121 (4), 1089-1098, 1995 | 213 | 1995 |
Role of SCL/Tal-1, GATA, and Ets transcription factor binding sites for the regulation of Flk-1 expression during murine vascular development A Kappel, TM Schlaeger, I Flamme, SH Orkin, W Risau, G Breier Blood, The Journal of the American Society of Hematology 96 (9), 3078-3085, 2000 | 202 | 2000 |
Endothelium‐specific replacement of the connexin43 coding region by a lacZ reporter gene M Theis, C de Wit, TM Schlaeger, D Eckardt, O Krüger, B Döring, W Risau, ... genesis 29 (1), 1-13, 2001 | 201 | 2001 |
Teratoma formation assays with human embryonic stem cells: a rationale for one type of human-animal chimera MW Lensch, TM Schlaeger, LI Zon, GQ Daley Cell stem cell 1 (3), 253-258, 2007 | 173 | 2007 |
Overcoming reprogramming resistance of Fanconi anemia cells LUW Müller, MD Milsom, CE Harris, R Vyas, KM Brumme, K Parmar, ... Blood, The Journal of the American Society of Hematology 119 (23), 5449-5457, 2012 | 161 | 2012 |
Using CRISPR-Cas9 to generate gene-corrected autologous iPSCs for the treatment of inherited retinal degeneration ER Burnight, M Gupta, LA Wiley, KR Anfinson, A Tran, R Triboulet, ... Molecular Therapy 25 (9), 1999-2013, 2017 | 154 | 2017 |
Derivation of airway basal stem cells from human pluripotent stem cells FJ Hawkins, S Suzuki, ML Beermann, C Barillà, R Wang, ... Cell Stem Cell 28 (1), 79-95. e8, 2021 | 153 | 2021 |
Improved electrospray ionization efficiency compensates for diminished chromatographic resolution and enables proteomics analysis of tyrosine signaling in embryonic stem cells SB Ficarro, Y Zhang, Y Lu, AR Moghimi, M Askenazi, E Hyatt, ED Smith, ... Analytical chemistry 81 (9), 3440-3447, 2009 | 132 | 2009 |
Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment P Li, JL Lahvic, V Binder, EK Pugach, EB Riley, OJ Tamplin, D Panigrahy, ... Nature 523 (7561), 468-471, 2015 | 130 | 2015 |
Tie2Cre-mediated gene ablation defines the stem-cell leukemia gene (SCL/tal1)–dependent window during hematopoietic stem-cell development TM Schlaeger, HKA Mikkola, C Gekas, HB Helgadottir, SH Orkin Blood 105 (10), 3871-3874, 2005 | 127 | 2005 |