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Shen Shichen
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Mature neutrophils suppress T cell immunity in ovarian cancer microenvironment
SBH Singel KL, Emmons TR, Khan ANH, Mayor PC, Shen S, Wong JT, Morrell K ...
JCI Insight 4 (5), e122311, 2019
1102019
Time-resolved analysis of proteome dynamics by tandem mass tags and stable isotope labeling in cell culture (TMT-SILAC) hyperplexing
KA Welle, T Zhang, JR Hryhorenko, S Shen, J Qu, S Ghaemmaghami
Molecular & Cellular Proteomics 15 (12), 3551-3563, 2016
912016
Global analysis of cellular protein flux quantifies the selectivity of basal autophagy
T Zhang, S Shen, J Qu, S Ghaemmaghami
Cell reports 14 (10), 2426-2439, 2016
882016
IonStar enables high-precision, low-missing-data proteomics quantification in large biological cohorts
X Shen, S Shen, J Li, Q Hu, L Nie, C Tu, X Wang, DJ Poulsen, BC Orsburn, ...
Proceedings of the National Academy of Sciences 115 (21), E4767-E4776, 2018
812018
Comparative proteomic analysis of the mitochondria-associated ER membrane (MAM) in a long-term type 2 diabetic rodent model
JH Ma, S Shen, JJ Wang, Z He, A Poon, J Li, J Qu, SX Zhang
Scientific reports 7 (1), 2062, 2017
792017
A comparative study of evaluating missing value imputation methods in label-free proteomics
L Jin, Y Bi, C Hu, J Qu, S Shen, X Wang, Y Tian
Scientific reports 11 (1), 1760, 2021
752021
An IonStar experimental strategy for MS1 ion current-based quantification using ultrahigh-field orbitrap: reproducible, in-depth, and accurate protein measurement in large cohorts
X Shen, S Shen, J Li, Q Hu, L Nie, C Tu, X Wang, B Orsburn, J Wang, J Qu
Journal of proteome research 16 (7), 2445-2456, 2017
742017
Qualitative and quantitative characterization of protein biotherapeutics with liquid chromatography mass spectrometry
M Qu, B An, S Shen, M Zhang, X Shen, X Duan, JP Balthasar, J Qu
Mass Spectrometry Reviews 36 (6), 734-754, 2017
642017
MS1 ion current‐based quantitative proteomics: A promising solution for reliable analysis of large biological cohorts
X Wang, S Shen, SS Rasam, J Qu
Mass spectrometry reviews 38 (6), 461-482, 2019
492019
Comparative characterization of osteoclasts derived from murine bone marrow macrophages and RAW 264.7 cells using quantitative proteomics
AYH Ng, C Tu, S Shen, D Xu, MJ Oursler, J Qu, S Yang
JBMR Plus, 2018
432018
Surfactant cocktail-aided extraction/precipitation/on-pellet digestion strategy enables efficient and reproducible sample preparation for large-scale quantitative proteomics
S Shen, B An, X Wang, SP Hilchey, J Li, J Cao, Y Tian, C Hu, L Jin, A Ng, ...
Analytical chemistry 90 (17), 10350-10359, 2018
392018
Sensitive, high-throughput, and robust trapping-micro-LC-MS strategy for the quantification of biomarkers and antibody biotherapeutics
M Zhang, B An, Y Qu, S Shen, W Fu, YJ Chen, X Wang, R Young, ...
Analytical chemistry 90 (3), 1870-1880, 2018
332018
Regulation of OATP1B1 function by tyrosine kinase–mediated phosphorylation
ER Hayden, M Chen, KZ Pasquariello, AA Gibson, JJ Petti, S Shen, J Qu, ...
Clinical Cancer Research 27 (15), 4301-4310, 2021
302021
Performance investigation of proteomic identification by HCD/CID fragmentations in combination with high/low-resolution detectors on a tribrid, high-field orbitrap instrument
C Tu, J Li, S Shen, Q Sheng, Y Shyr, J Qu
PloS one 11 (7), e0160160, 2016
282016
A novel PDE4D inhibitor BPN14770 reverses scopolamine-induced cognitive deficits via cAMP/SIRT1/Akt/Bcl-2 pathway
Y Wang, S Gao, V Zheng, L Chen, M Ma, S Shen, J Qu, H Zhang, ...
Frontiers in Cell and Developmental Biology 8, 599389, 2020
252020
Protein acylation by saturated very long chain fatty acids and endocytosis are involved in necroptosis
AJ Pradhan, D Lu, LR Parisi, S Shen, IA Berhane, SL Galster, K Bynum, ...
Cell chemical biology 28 (9), 1298-1309. e7, 2021
242021
Regulation of local GTP availability controls RAC1 activity and cell invasion
A Bianchi-Smiraglia, DW Wolff, DJ Marston, Z Deng, Z Han, S Moparthy, ...
Nature communications 12 (1), 1-15, 2021
222021
Temporal effects of combined birinapant and paclitaxel on pancreatic cancer cells investigated via large-scale, ion-current-based quantitative proteomics (IonStar)
X Wang, J Niu, J Li, X Shen, S Shen, RM Straubinger, J Qu
Molecular & Cellular Proteomics 17 (4), 655-671, 2018
212018
Parallel, high-quality proteomic and targeted metabolomic quantification using laser capture microdissected tissues
S Shen, J Li, S Huo, M Ma, X Zhu, S Rasam, X Duan, M Qu, MA Titus, ...
Analytical chemistry 93 (25), 8711-8718, 2021
162021
A mechanism of gene evolution generating mucin function
P Pajic, S Shen, J Qu, AJ May, S Knox, S Ruhl, O Gokcumen
Science advances 8 (34), eabm8757, 2022
152022
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