Targeting Hedgehog—a cancer stem cell pathway AA Merchant, W Matsui Clinical cancer research 16 (12), 3130-3140, 2010 | 619 | 2010 |
Molecular signatures of proliferation and quiescence in hematopoietic stem cells TA Venezia, AA Merchant, CA Ramos, NL Whitehouse, AS Young, ... PLoS biology 2 (10), e301, 2004 | 429 | 2004 |
Hematopoietic fingerprints: an expression database of stem cells and their progeny SM Chambers, NC Boles, KYK Lin, MP Tierney, TV Bowman, SB Bradfute, ... Cell stem cell 1 (5), 578-591, 2007 | 326 | 2007 |
GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein E Beauchamp, G Bulut, O Abaan, K Chen, A Merchant, W Matsui, Y Endo, ... Journal of Biological Chemistry 284 (14), 9074-9082, 2009 | 185 | 2009 |
Single-cell transcriptome analysis reveals disease-defining T-cell subsets in the tumor microenvironment of classic Hodgkin lymphoma T Aoki, LC Chong, K Takata, K Milne, M Hav, A Colombo, EA Chavez, ... Cancer discovery 10 (3), 406-421, 2020 | 182 | 2020 |
Hepatic adverse event profile of inotuzumab ozogamicin in adult patients with relapsed or refractory acute lymphoblastic leukaemia: results from the open-label, randomised … HM Kantarjian, DJ DeAngelo, AS Advani, M Stelljes, P Kebriaei, ... The Lancet Haematology 4 (8), e387-e398, 2017 | 169 | 2017 |
Gli1 regulates the proliferation and differentiation of HSCs and myeloid progenitors A Merchant, G Joseph, Q Wang, S Brennan, W Matsui Blood, The Journal of the American Society of Hematology 115 (12), 2391-2396, 2010 | 129 | 2010 |
The redox-sensitive transcription factor Nrf2 regulates murine hematopoietic stem cell survival independently of ROS levels AA Merchant, A Singh, W Matsui, S Biswal Blood, The Journal of the American Society of Hematology 118 (25), 6572-6579, 2011 | 127 | 2011 |
Glasdegib in combination with cytarabine and daunorubicin in patients with AML or high‐risk MDS: phase 2 study results JE Cortes, B Douglas Smith, ES Wang, A Merchant, VG Oehler, ... American journal of hematology 93 (11), 1301-1310, 2018 | 123 | 2018 |
Not so benign haematology: anaemia of the elderly AA Merchant, CN Roy British journal of haematology 156 (2), 173-185, 2012 | 112 | 2012 |
Management of important adverse events associated with inotuzumab ozogamicin: expert panel review P Kebriaei, C Cutler, M De Lima, S Giralt, SJ Lee, D Marks, A Merchant, ... Bone marrow transplantation 53 (4), 449-456, 2018 | 107 | 2018 |
Self-renewal of acute lymphocytic leukemia cells is limited by the Hedgehog pathway inhibitors cyclopamine and IPI-926 TL Lin, QH Wang, P Brown, C Peacock, AA Merchant, S Brennan, E Jones, ... Plos one 5 (12), e15262, 2010 | 101 | 2010 |
Periodontal inflammation recruits distant metastatic breast cancer cells by increasing myeloid-derived suppressor cells R Cheng, S Billet, C Liu, S Haldar, D Choudhury, M Tripathi, M Hav, ... Oncogene 39 (7), 1543-1556, 2020 | 72 | 2020 |
GLI3 repressor determines Hedgehog pathway activation and is required for response to SMO antagonist glasdegib in AML P Chaudhry, M Singh, TJ Triche, M Guzman, AA Merchant Blood, The Journal of the American Society of Hematology 129 (26), 3465-3475, 2017 | 71 | 2017 |
Multiplex protein detection on circulating tumor cells from liquid biopsies using imaging mass cytometry E Gerdtsson, M Pore, JA Thiele, AS Gerdtsson, PD Malihi, R Nevarez, ... Convergent science physical oncology 4 (1), 015002, 2018 | 69 | 2018 |
Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia Y Lim, L Gondek, L Li, Q Wang, H Ma, E Chang, DL Huso, S Foerster, ... Science translational medicine 7 (291), 291ra96-291ra96, 2015 | 61 | 2015 |
Evidence for diversity in transcriptional profiles of single hematopoietic stem cells CA Ramos, TA Bowman, NC Boles, AA Merchant, Y Zheng, I Parra, ... PLoS genetics 2 (9), e159, 2006 | 61 | 2006 |
Outcomes of allogeneic stem cell transplantation after inotuzumab ozogamicin treatment for relapsed or refractory acute lymphoblastic leukemia DI Marks, P Kebriaei, M Stelljes, N Gökbuget, H Kantarjian, AS Advani, ... Biology of Blood and Marrow Transplantation 25 (9), 1720-1729, 2019 | 59 | 2019 |
Primary cilia are present on human blood and bone marrow cells and mediate Hedgehog signaling M Singh, P Chaudhry, AA Merchant Experimental Hematology 44 (12), 1181-1187. e2, 2016 | 56 | 2016 |
Glasdegib plus intensive/nonintensive chemotherapy in untreated acute myeloid leukemia: BRIGHT AML 1019 Phase III trials JE Cortes, H Dombret, A Merchant, T Tauchi, CG DiRienzo, B Sleight, ... Future Oncology 15 (31), 3531-3545, 2019 | 50 | 2019 |