Selective inhibition of biotin protein ligase from Staphylococcus aureus TPS Da Costa, W Tieu, MY Yap, NR Pendini, SW Polyak, DS Pedersen, ... Journal of Biological Chemistry 287 (21), 17823-17832, 2012 | 79 | 2012 |
5-Benzylidenerhodanine and 5-benzylidene-2-4-thiazolidinedione based antibacterials O Zvarec, SW Polyak, W Tieu, K Kuan, H Dai, DS Pedersen, R Morona, ... Bioorganic & medicinal chemistry letters 22 (8), 2720-2722, 2012 | 60 | 2012 |
Biotin analogues with antibacterial activity are potent inhibitors of biotin protein ligase TP Soares da Costa, W Tieu, MY Yap, O Zvarec, JM Bell, JD Turnidge, ... ACS Medicinal Chemistry Letters 3 (6), 509-514, 2012 | 53 | 2012 |
New cholesterol esterase inhibitors based on rhodanine and thiazolidinedione scaffolds S Heng, W Tieu, S Hautmann, K Kuan, DS Pedersen, M Pietsch, ... Bioorganic & medicinal chemistry 19 (24), 7453-7463, 2011 | 52 | 2011 |
Exploiting the biosynthetic machinery of Streptomyces pilosus to engineer a water-soluble zirconium (iv) chelator T Richardson-Sanchez, W Tieu, MP Gotsbacher, TJ Telfer, R Codd Organic & Biomolecular Chemistry 15 (27), 5719-5730, 2017 | 50 | 2017 |
Optimising in situ click chemistry: the screening and identification of biotin protein ligase inhibitors W Tieu, TPS Da Costa, MY Yap, KL Keeling, MCJ Wilce, JC Wallace, ... Chemical Science 4 (9), 3533-3537, 2013 | 45 | 2013 |
Octadentate zirconium (IV)-loaded macrocycles with varied stoichiometry assembled from hydroxamic acid monomers using metal-templated synthesis W Tieu, T Lifa, A Katsifis, R Codd Inorganic chemistry 56 (6), 3719-3728, 2017 | 37 | 2017 |
Immuno-PET of innate immune markers CD11b and IL-1β detects inflammation in murine colitis N Dmochowska, W Tieu, MD Keller, HR Wardill, C Mavrangelos, ... Journal of Nuclear Medicine 60 (6), 858-863, 2019 | 33 | 2019 |
Rapid and automated production of [68Ga] gallium chloride and [68Ga] Ga-DOTA-TATE on a medical cyclotron W Tieu, CA Hollis, KKW Kuan, P Takhar, M Stuckings, N Spooner, ... Nuclear Medicine and Biology 74, 12-18, 2019 | 31 | 2019 |
Structure guided design of biotin protein ligase inhibitors for antibiotic discovery A S Paparella, T P Soares da Costa, M Y Yap, W Tieu, M CJ Wilce, ... Current topics in medicinal chemistry 14 (1), 4-20, 2014 | 28 | 2014 |
Heterocyclic acyl-phosphate bioisostere-based inhibitors of Staphylococcus aureus biotin protein ligase W Tieu, AM Jarrad, AS Paparella, KA Keeling, TPS Da Costa, JC Wallace, ... Bioorganic & Medicinal Chemistry Letters 24 (19), 4689-4693, 2014 | 25 | 2014 |
Improved synthesis of biotinol-5′-AMP: Implications for antibacterial discovery W Tieu, SW Polyak, AS Paparella, MY Yap, TP Soares da Costa, B Ng, ... ACS Medicinal Chemistry Letters 6 (2), 216-220, 2015 | 22 | 2015 |
Forward and reverse (retro) iron (III) or gallium (III) desferrioxamine E and ring-expanded analogues prepared using metal-templated synthesis from endo-hydroxamic acid monomers T Lifa, W Tieu, RK Hocking, R Codd Inorganic Chemistry 54 (7), 3573-3583, 2015 | 19 | 2015 |
The chemical biology and coordination chemistry of putrebactin, avaroferrin, bisucaberin, and alcaligin R Codd, CZ Soe, AAH Pakchung, A Sresutharsan, CJM Brown, W Tieu JBIC Journal of Biological Inorganic Chemistry 23, 969-982, 2018 | 17 | 2018 |
New Series of BPL Inhibitors To Probe the Ribose-Binding Pocket of Staphylococcus aureus Biotin Protein Ligase J Feng, AS Paparella, W Tieu, D Heim, S Clark, A Hayes, GW Booker, ... ACS Medicinal Chemistry Letters 7 (12), 1068-1072, 2016 | 17 | 2016 |
Analogues of desferrioxamine B (DFOB) with new properties and new functions generated using precursor-directed biosynthesis TJ Telfer, T Richardson-Sanchez, MP Gotsbacher, KP Nolan, W Tieu, ... Biometals 32, 395-408, 2019 | 14 | 2019 |
Toll-like receptors change morphine-induced antinociception, tolerance and dependence: Studies using male and female TLR and signalling gene KO mice JHL Thomas, L Lui, A Abell, W Tieu, AA Somogyi, JE Bajic, ... Brain, behavior, and immunity 102, 71-85, 2022 | 12 | 2022 |
Improved non-invasive positron emission tomographic imaging of chemotherapy-induced tumor cell death using Zirconium-89-labeled APOMABŪ V Liapis, W Tieu, SE Rudd, PS Donnelly, NL Wittwer, MP Brown, ... EJNMMI radiopharmacy and chemistry 5, 1-15, 2020 | 11 | 2020 |
Dimeric and trimeric homo-and heteroleptic hydroxamic acid macrocycles formed using mixed-ligand Fe (III)-based metal-templated synthesis A Sresutharsan, W Tieu, T Richardson-Sanchez, CZ Soe, R Codd Journal of Inorganic Biochemistry 177, 344-351, 2017 | 11 | 2017 |
Sulfonamide-based inhibitors of biotin protein ligase as new antibiotic leads KJ Lee, W Tieu, B Blanco-Rodriguez, AS Paparella, J Yu, A Hayes, ... ACS Chemical Biology 14 (9), 1990-1997, 2019 | 9 | 2019 |