Calcium-sensing receptor antagonists abrogate airway hyperresponsiveness and inflammation in allergic asthma PL Yarova, AL Stewart, V Sathish, RD Britt Jr, MA Thompson, AP P. Lowe, ... Science translational medicine 7 (284), 284ra60-284ra60, 2015 | 181 | 2015 |
The vascular Ca2+-sensing receptor regulates blood vessel tone and blood pressure M Schepelmann, PL Yarova, I Lopez-Fernandez, TS Davies, SC Brennan, ... American Journal of Physiology-Cell Physiology 310 (3), C193-C204, 2016 | 90 | 2016 |
Comparative expression of the extracellular calcium-sensing receptor in the mouse, rat, and human kidney JAZ Graca, M Schepelmann, SC Brennan, J Reens, W Chang, P Yan, ... American Journal of Physiology-Renal Physiology 310 (6), F518-F533, 2016 | 69 | 2016 |
Emerging roles of the extracellular calcium-sensing receptor in nutrient sensing: control of taste modulation and intestinal hormone secretion SC Brennan, TS Davies, M Schepelmann, D Riccardi British journal of nutrition 111 (S1), S16-S22, 2014 | 64 | 2014 |
Calcium-sensing receptor in colorectal inflammation and cancer: Current insights and future perspectives L Iamartino, T Elajnaf, E Kallay, M Schepelmann World Journal of Gastroenterology 24 (36), 4119, 2018 | 52 | 2018 |
Treatment of autosomal dominant hypocalcemia type 1 with the calcilytic NPSP795 (SHP635) MS Roberts, RI Gafni, B Brillante, LC Guthrie, J Streit, D Gash, J Gelb, ... Journal of Bone and Mineral Research 34 (9), 1609-1618, 2019 | 44 | 2019 |
The presence and localization of melatonin receptors in the rat aorta M Schepelmann, L Molcan, H Uhrova, M Zeman, I Ellinger Cellular and molecular neurobiology 31, 1257-1265, 2011 | 34 | 2011 |
The calcium‐sensing receptor: one of a kind I Lopez‐Fernandez, M Schepelmann, SC Brennan, PL Yarova, D Riccardi Experimental physiology 100 (12), 1392-1399, 2015 | 31 | 2015 |
Expression of the neonatal Fc-receptor in placental-fetal endothelium and in cells of the placental immune system T Kiskova, Y Mytsko, M Schepelmann, H Helmer, R Fuchs, H Miedl, ... Placenta 78, 36-43, 2019 | 24 | 2019 |
Nutritional and pharmacological targeting of the calcium-sensing receptor influences chemically induced colitis in mice T Elajnaf, L Iamartino, I Mesteri, C Müller, M Bassetto, T Manhardt, ... Nutrients 11 (12), 3072, 2019 | 22 | 2019 |
Characterization of negative allosteric modulators of the calcium-sensing receptor for repurposing as a treatment of asthma PL Yarova, P Huang, MW Schepelmann, R Bruce, R Ecker, R Nica, ... Journal of Pharmacology and Experimental Therapeutics 376 (1), 51-63, 2021 | 19 | 2021 |
Switching to a healthy diet prevents the detrimental effects of Western diet in a colitis-associated colorectal cancer model C Gröschel, M Prinz-Wohlgenannt, I Mesteri, S Karuthedom George, ... Nutrients 12 (1), 45, 2019 | 18 | 2019 |
AOM/DSS Induced Colitis-Associated Colorectal Cancer in 14-Month-Old Female Balb/C and C57/Bl6 Mice—A Pilot Study M Schepelmann, N Kupper, V Gushchina, I Mesteri, T Manhardt, ... International Journal of Molecular Sciences 23 (9), 5278, 2022 | 15 | 2022 |
Effects of pharmacological calcimimetics on colorectal cancer cells over-expressing the human calcium-sensing receptor L Iamartino, T Elajnaf, K Gall, J David, T Manhardt, P Heffeter, M Grusch, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1867 (12), 118836, 2020 | 13 | 2020 |
Impaired mineral ion metabolism in a mouse model of targeted calcium-sensing receptor (CaSR) deletion from vascular smooth muscle cells M Schepelmann, M Ranieri, I Lopez-Fernandez, TS Webberley, ... Journal of the American Society of Nephrology 33 (7), 1323-1340, 2022 | 12 | 2022 |
Computational studies towards the identification of novel rhodopsin-binding compounds as chemical chaperones for misfolded opsins G Pasqualetto, M Schepelmann, C Varricchio, E Pileggi, C Khogali, ... Molecules 25 (21), 4904, 2020 | 12 | 2020 |
Vitamin d analogs regulate the vitamin d system and cell viability in ovarian cancer cells K Piatek, A Kutner, D Cacsire Castillo-Tong, T Manhardt, N Kupper, ... International Journal of Molecular Sciences 23 (1), 172, 2021 | 10 | 2021 |
The effect of vitamin D and its analogs in ovarian cancer K Piatek, M Schepelmann, E Kallay Nutrients 14 (18), 3867, 2022 | 9 | 2022 |
Stereo-specific modulation of the extracellular calcium-sensing receptor in colon cancer cells M Schepelmann, N Kupper, M Sladczyk, B Mansfield, T Manhardt, ... International Journal of Molecular Sciences 22 (18), 10124, 2021 | 9 | 2021 |
Ligand-based rational design, synthesis and evaluation of novel potential chemical chaperones for opsin G Pasqualetto, E Pileggi, M Schepelmann, C Varricchio, M Rozanowska, ... European Journal of Medicinal Chemistry 226, 113841, 2021 | 7 | 2021 |