| Bioengineered 3D platform to explore cell–ECM interactions and drug resistance of epithelial ovarian cancer cells D Loessner, KS Stok, MP Lutolf, DW Hutmacher, JA Clements, SC Rizzi Biomaterials 31 (32), 8494-8506, 2010 | 738 | 2010 |
| Functionalization, preparation and use of cell-laden gelatin methacryloyl–based hydrogels as modular tissue culture platforms D Loessner, C Meinert, E Kaemmerer, LC Martine, K Yue, PA Levett, ... Nature protocols 11 (4), 727-746, 2016 | 721 | 2016 |
| Can tissue engineering concepts advance tumor biology research? DW Hutmacher, D Loessner, S Rizzi, DL Kaplan, DJ Mooney, ... Trends in biotechnology 28 (3), 125-133, 2010 | 281 | 2010 |
| Design and fabrication of tubular scaffolds via direct writing in a melt electrospinning mode TD Brown, A Slotosch, L Thibaudeau, A Taubenberger, D Loessner, ... Biointerphases 7 (1-4), 1-16, 2012 | 261 | 2012 |
| Discrepancies between metabolic activity and DNA content as tool to assess cell proliferation in cancer research VMC Quent, D Loessner, T Friis, JC Reichert, DW Hutmacher Journal of cellular and molecular medicine 14 (4), 1003-1013, 2010 | 259 | 2010 |
| Gelatine methacrylamide-based hydrogels: an alternative three-dimensional cancer cell culture system E Kaemmerer, FPW Melchels, BM Holzapfel, T Meckel, DW Hutmacher, ... Acta biomaterialia 10 (6), 2551-2562, 2014 | 233 | 2014 |
| Translating tissue engineering technology platforms into cancer research DW Hutmacher, RE Horch, D Loessner, S Rizzi, S Sieh, JC Reichert, ... Journal of cellular and molecular medicine 13 (8a), 1417-1427, 2009 | 184 | 2009 |
| Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells MG Lawrence, NV Margaryan, D Loessner, A Collins, KM Kerr, M Turner, ... The Prostate 71 (11), 1198-1209, 2011 | 126 | 2011 |
| Species-specific homing mechanisms of human prostate cancer metastasis in tissue engineered bone BM Holzapfel, F Wagner, D Loessner, NP Holzapfel, L Thibaudeau, ... Biomaterials 35 (13), 4108-4115, 2014 | 121 | 2014 |
| Kallikrein-related peptidase 7 promotes multicellular aggregation via the α5β1 integrin pathway and paclitaxel chemoresistance in serous epithelial ovarian carcinoma Y Dong, OL Tan, D Loessner, C Stephens, C Walpole, GM Boyle, ... Cancer research 70 (7), 2624-2633, 2010 | 110 | 2010 |
| The kallikrein-related peptidase family: Dysregulation and functions during cancer progression T Kryza, ML Silva, D Loessner, N Heuzé-Vourc'h, JA Clements Biochimie 122, 283-299, 2016 | 103 | 2016 |
| 3D approaches to model the tumor microenvironment of pancreatic cancer E Tomás-Bort, M Kieler, S Sharma, JB Candido, D Loessner Theranostics 10 (11), 5074, 2020 | 95 | 2020 |
| Tissue engineered humanized bone supports human hematopoiesis in vivo BM Holzapfel, DW Hutmacher, B Nowlan, V Barbier, L Thibaudeau, ... Biomaterials 61, 103-114, 2015 | 84 | 2015 |
| Endosteal-like extracellular matrix expression on melt electrospun written scaffolds ML Muerza-Cascante, A Shokoohmand, K Khosrotehrani, D Haylock, ... Acta biomaterialia 52, 145-158, 2017 | 79 | 2017 |
| TGFBI production by macrophages contributes to an immunosuppressive microenvironment in ovarian cancer LSM Lecker, C Berlato, E Maniati, R Delaine-Smith, OMT Pearce, O Heath, ... Cancer Research 81 (22), 5706-5719, 2021 | 73 | 2021 |
| The reduced expression of the HADH2 protein causes X-linked mental retardation, choreoathetosis, and abnormal behavior C Lenski, RF Kooy, E Reyniers, D Loessner, RJA Wanders, ... The American Journal of Human Genetics 80 (2), 372-377, 2007 | 72 | 2007 |
| A bioengineered 3D ovarian cancer model for the assessment of peptidase–mediated enhancement of spheroid growth and intraperitoneal spread D Loessner, SC Rizzi, KS Stok, T Fuehrmann, B Hollier, V Magdolen, ... Biomaterials 34 (30), 7389-7400, 2013 | 71 | 2013 |
| Bioengineered 3D models of human pancreatic cancer recapitulate in vivo tumour biology D Osuna de la Peña, SMD Trabulo, E Collin, Y Liu, S Sharma, M Tatari, ... Nature Communications 12 (1), 5623, 2021 | 70 | 2021 |
| Secretome and degradome profiling shows that Kallikrein-related peptidases 4, 5, 6, and 7 induce TGFβ-1 signaling in ovarian cancer cells H Shahinian, D Loessner, ML Biniossek, JN Kizhakkedathu, JA Clements, ... Molecular oncology 8 (1), 68-82, 2014 | 69 | 2014 |
| Growth of confined cancer spheroids: a combined experimental and mathematical modelling approach D Loessner, JA Flegg, HM Byrne, JA Clements, DW Hutmacher Integrative Biology 5 (3), 597-605, 2013 | 68 | 2013 |
