Selective positive modulator of calcium-activated potassium channels exerts beneficial effects in a mouse model of spinocerebellar ataxia type 2 AW Kasumu, C Hougaard, F Rode, TA Jacobsen, JM Sabatier, BL Eriksen, ... Chemistry & biology 19 (10), 1340-1353, 2012 | 171 | 2012 |
Enhanced store-operated calcium entry leads to striatal synaptic loss in a Huntington's disease mouse model J Wu, DA Ryskamp, X Liang, P Egorova, O Zakharova, G Hung, ... Journal of neuroscience 36 (1), 125-141, 2016 | 156 | 2016 |
Chronic suppression of inositol 1, 4, 5-triphosphate receptor-mediated calcium signaling in cerebellar purkinje cells alleviates pathological phenotype in spinocerebellar … AW Kasumu, X Liang, P Egorova, D Vorontsova, I Bezprozvanny Journal of Neuroscience 32 (37), 12786-12796, 2012 | 129 | 2012 |
Inositol 1, 4, 5‐trisphosphate receptors and neurodegenerative disorders PA Egorova, IB Bezprozvanny The FEBS journal 285 (19), 3547-3565, 2018 | 91 | 2018 |
Disturbed calcium signaling in spinocerebellar ataxias and Alzheimer's disease P Egorova, E Popugaeva, I Bezprozvanny Seminars in cell & developmental biology 40, 127-133, 2015 | 70 | 2015 |
In vivo analysis of cerebellar Purkinje cell activity in SCA2 transgenic mouse model PA Egorova, OA Zakharova, OL Vlasova, IB Bezprozvanny Journal of neurophysiology 115 (6), 2840-2851, 2016 | 68 | 2016 |
Molecular mechanisms and therapeutics for spinocerebellar ataxia type 2 PA Egorova, IB Bezprozvanny Neurotherapeutics 16 (4), 1050-1073, 2019 | 48 | 2019 |
Ataxic symptoms in Huntington’s disease transgenic mouse model are alleviated by chlorzoxazone PA Egorova, AV Gavrilova, IB Bezprozvanny Frontiers in neuroscience 14, 279, 2020 | 19 | 2020 |
Structure–Activity Relationship Study of Subtype-Selective Positive Modulators of KCa2 Channels NS El-Sayed, YW Nam, PA Egorova, HM Nguyen, R Orfali, MA Rahman, ... Journal of medicinal chemistry 65 (1), 303-322, 2021 | 14 | 2021 |
In vivo analysis of the climbing fiber-Purkinje cell circuit in SCA2-58Q transgenic mouse model PA Egorova, AV Gavrilova, IB Bezprozvanny The Cerebellum 17, 590-600, 2018 | 13 | 2018 |
The effect of SK channel modulators on the simple spike firing frequency in discharge of cerebellar Purkinje cells in laboratory mice PA Egorova, TV Karelina, OL Vlasova, SM Antonov, IB Bezprozvanny Journal of Evolutionary Biochemistry and Physiology 50, 114-120, 2014 | 11 | 2014 |
In vivo analysis of the spontaneous firing of cerebellar Purkinje cells in awake transgenic mice that model spinocerebellar ataxia type 2 PA Egorova, AV Gavrilova, IB Bezprozvanny Cell Calcium 93, 102319, 2021 | 10 | 2021 |
Electrophysiological studies support utility of positive modulators of SK channels for the treatment of spinocerebellar ataxia type 2 PA Egorova, IB Bezprozvanny The Cerebellum, 1-8, 2022 | 9 | 2022 |
A chlorzoxazone–folic acid combination improves cognitive affective decline in SCA2-58Q mice KS Marinina, IB Bezprozvanny, PA Egorova Scientific reports 13 (1), 12588, 2023 | 7 | 2023 |
Chronic suppression of STIM1-mediated calcium signaling in Purkinje cells rescues the cerebellar pathology in spinocerebellar ataxia type 2 PA Egorova, KS Marinina, IB Bezprozvanny Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1870 (5), 119466, 2023 | 7 | 2023 |
An automated and quantitative method to evaluate progression of striatal pathology in Huntington's disease transgenic mice X Liang, J Wu, P Egorova, I Bezprozvanny Journal of Huntington's disease 3 (4), 343-350, 2014 | 6 | 2014 |
Cognitive decline and mood alterations in the mouse model of spinocerebellar ataxia type 2 KS Marinina, IB Bezprozvanny, PA Egorova The Cerebellum 23 (1), 145-161, 2024 | 5 | 2024 |
Memory decline, anxiety and depression in the mouse model of spinocerebellar ataxia type 3 KS Marinina, IB Bezprozvanny, PA Egorova Human molecular genetics 33 (4), 299-317, 2024 | 2 | 2024 |
The effect of modulators of SK channels on simple spike firing frequency in the discharge of the cerebellar Purkinje cells in laboratory mice PA Egorova, TV Karelina, OL Vlasova, SM Antonov, IB Besprozvanny Zhurnal Evoliutsionnoi Biokhimii i Fiziologii 50 (2), 102-108, 2014 | 2 | 2014 |
A combination of chlorzoxazone and folic acid improves recognition memory, anxiety and depression in SCA3-84Q mice KS Marinina, IB Bezprozvanny, PA Egorova Human Molecular Genetics, ddae079, 2024 | 1 | 2024 |