Insulin-dependent regulation of insulin receptor concentrations: a direct demonstration in cell culture JR Gavin III, J Roth, DM Neville Jr, P De Meyts, DN Buell Proceedings of the National Academy of Sciences 71 (1), 84-88, 1974 | 1438 | 1974 |
Insulin interactions with its receptors: experimental evidence for negative cooperativity P De Meyts, J Roth, DM Neville Jr, JR Gavin III, MA Lesniak Biochemical and biophysical research communications 55 (1), 154-161, 1973 | 855 | 1973 |
Site-site interactions among insulin receptors: characterization of the negative cooperativity. DE Meyts P, B AR, R J Journal of Biological Chemistry 251, 1877-1888, 1976 | 782 | 1976 |
Structural biology of insulin and IGF1 receptors: implications for drug design P De Meyts, J Whittaker Nature reviews Drug discovery 1 (10), 769-783, 2002 | 770 | 2002 |
Fluctuations in the affinity and concentration of insulin receptors on circulating monocytes of obese patients: effects of starvation, refeeding, and dieting. RS Bar, P Gorden, J Roth, CR Kahn, P De Meyts The Journal of clinical investigation 58 (5), 1123-1135, 1976 | 588 | 1976 |
Cooperativity in ligand binding: a new graphic analysis P De Meyts, J Roth Biochemical and biophysical research communications 66 (4), 1118-1126, 1975 | 506 | 1975 |
Insulin and its receptor: structure, function and evolution P De Meyts Bioessays 26 (12), 1351-1362, 2004 | 453 | 2004 |
The structural basis of insulin and insulin-like growth factor-I receptor binding and negative co-operativity, and its relevance to mitogenic versus metabolic signalling P De Meyts Diabetologia 37 (Suppl 2), S135-S148, 1994 | 351 | 1994 |
The insulin-like growth factor-I receptor: structure, ligand-binding mechanism and signal transduction P De Meyts, B Wallach, CT Christoffersen, B Ursø, K Grønskov, LJ Latus, ... Hormone Research in Paediatrics 42 (4-5), 152-169, 1994 | 310 | 1994 |
Alterations in insulin binding induced by changes in vivo in the levels of glucocorticoids and growth hormone C RONALD KAHN, IRAD GOLDFINE, DM NEVILLE JR, P DE MEYTS Endocrinology 103 (4), 1054-1066, 1978 | 308 | 1978 |
The insulin receptor and its signal transduction network P De Meyts Endotext [Internet], 2016 | 298 | 2016 |
Mapping of the residues responsible for the negative cooperativity of the receptor-binding region of insulin PD Meyts, E Van Obberghen, J Roth, A Wollmer, D Brandenburg Nature 273 (5663), 504-509, 1978 | 256 | 1978 |
Receptors for insulin, NSILA-s, and growth hormone: applications to disease states in man J ROTH, CR KAHN, MA LESNIAK, P GORDEN, P DE MEYTS, ... Proceedings of the 1974 Laurentian Hormone Conference, 95-139, 1975 | 248 | 1975 |
Mitogenic properties of insulin and insulin analogues mediated by the insulin receptor D Ish-Shalom, CT Christoffersen, P Vorwerk, N Sacerdoti-Sierra, ... Diabetologia 40, S25-S31, 1997 | 247 | 1997 |
β-Adrenergic receptors: Evidence for negative cooperativity LE Limbird, P De Meyts, RJ Lefkowitz Biochemical and biophysical research communications 64 (4), 1160-1168, 1975 | 236 | 1975 |
Cooperative properties of hormone receptors in cell membranes PD Meyts Journal of Supramolecular Structure 4 (2), 241-258, 1976 | 224 | 1976 |
The insulin receptor: a prototype for dimeric, allosteric membrane receptors? P De Meyts Trends in biochemical sciences 33 (8), 376-384, 2008 | 213 | 2008 |
The insulin receptor in vertebrates is functionally more conserved during evolution than insulin itself M MUGGEO, BH GINSBERG, J ROTH, DM NEVILLE JR, PDE MEYTS, ... Endocrinology 104 (5), 1393-1402, 1979 | 213 | 1979 |
Harmonic oscillator model of the insulin and IGF1 receptors’ allosteric binding and activation VV Kiselyov, S Versteyhe, L Gauguin, P De Meyts Molecular systems biology 5 (1), 243, 2009 | 204 | 2009 |
A highly sensitive and specific assay for determination of IGF-I bioactivity in human serum JW Chen, T Ledet, H Ørskov, N Jessen, S Lund, J Whittaker, P De Meyts, ... American Journal of Physiology-Endocrinology and Metabolism 284 (6), E1149-E1155, 2003 | 186 | 2003 |