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Pierre De Meyts, MD, PhD
Pierre De Meyts, MD, PhD
Visiting professor, de Duve Institute
Verified email at novonordisk.com
Title
Cited by
Cited by
Year
Insulin-dependent regulation of insulin receptor concentrations: a direct demonstration in cell culture
JR Gavin III, J Roth, DM Neville Jr, P De Meyts, DN Buell
Proceedings of the National Academy of Sciences 71 (1), 84-88, 1974
14381974
Insulin interactions with its receptors: experimental evidence for negative cooperativity
P De Meyts, J Roth, DM Neville Jr, JR Gavin III, MA Lesniak
Biochemical and biophysical research communications 55 (1), 154-161, 1973
8551973
Site-site interactions among insulin receptors: characterization of the negative cooperativity.
DE Meyts P, B AR, R J
Journal of Biological Chemistry 251, 1877-1888, 1976
7821976
Structural biology of insulin and IGF1 receptors: implications for drug design
P De Meyts, J Whittaker
Nature reviews Drug discovery 1 (10), 769-783, 2002
7702002
Fluctuations in the affinity and concentration of insulin receptors on circulating monocytes of obese patients: effects of starvation, refeeding, and dieting.
RS Bar, P Gorden, J Roth, CR Kahn, P De Meyts
The Journal of clinical investigation 58 (5), 1123-1135, 1976
5881976
Cooperativity in ligand binding: a new graphic analysis
P De Meyts, J Roth
Biochemical and biophysical research communications 66 (4), 1118-1126, 1975
5061975
Insulin and its receptor: structure, function and evolution
P De Meyts
Bioessays 26 (12), 1351-1362, 2004
4532004
The structural basis of insulin and insulin-like growth factor-I receptor binding and negative co-operativity, and its relevance to mitogenic versus metabolic signalling
P De Meyts
Diabetologia 37 (Suppl 2), S135-S148, 1994
3511994
The insulin-like growth factor-I receptor: structure, ligand-binding mechanism and signal transduction
P De Meyts, B Wallach, CT Christoffersen, B Ursø, K Grønskov, LJ Latus, ...
Hormone Research in Paediatrics 42 (4-5), 152-169, 1994
3101994
Alterations in insulin binding induced by changes in vivo in the levels of glucocorticoids and growth hormone
C RONALD KAHN, IRAD GOLDFINE, DM NEVILLE JR, P DE MEYTS
Endocrinology 103 (4), 1054-1066, 1978
3081978
The insulin receptor and its signal transduction network
P De Meyts
Endotext [Internet], 2016
2982016
Mapping of the residues responsible for the negative cooperativity of the receptor-binding region of insulin
PD Meyts, E Van Obberghen, J Roth, A Wollmer, D Brandenburg
Nature 273 (5663), 504-509, 1978
2561978
Receptors for insulin, NSILA-s, and growth hormone: applications to disease states in man
J ROTH, CR KAHN, MA LESNIAK, P GORDEN, P DE MEYTS, ...
Proceedings of the 1974 Laurentian Hormone Conference, 95-139, 1975
2481975
Mitogenic properties of insulin and insulin analogues mediated by the insulin receptor
D Ish-Shalom, CT Christoffersen, P Vorwerk, N Sacerdoti-Sierra, ...
Diabetologia 40, S25-S31, 1997
2471997
β-Adrenergic receptors: Evidence for negative cooperativity
LE Limbird, P De Meyts, RJ Lefkowitz
Biochemical and biophysical research communications 64 (4), 1160-1168, 1975
2361975
Cooperative properties of hormone receptors in cell membranes
PD Meyts
Journal of Supramolecular Structure 4 (2), 241-258, 1976
2241976
The insulin receptor: a prototype for dimeric, allosteric membrane receptors?
P De Meyts
Trends in biochemical sciences 33 (8), 376-384, 2008
2132008
The insulin receptor in vertebrates is functionally more conserved during evolution than insulin itself
M MUGGEO, BH GINSBERG, J ROTH, DM NEVILLE JR, PDE MEYTS, ...
Endocrinology 104 (5), 1393-1402, 1979
2131979
Harmonic oscillator model of the insulin and IGF1 receptors’ allosteric binding and activation
VV Kiselyov, S Versteyhe, L Gauguin, P De Meyts
Molecular systems biology 5 (1), 243, 2009
2042009
A highly sensitive and specific assay for determination of IGF-I bioactivity in human serum
JW Chen, T Ledet, H Ørskov, N Jessen, S Lund, J Whittaker, P De Meyts, ...
American Journal of Physiology-Endocrinology and Metabolism 284 (6), E1149-E1155, 2003
1862003
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