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José María Ayuso Domínguez
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Development and characterization of a microfluidic model of the tumour microenvironment
JM Ayuso, M Virumbrales-Muñoz, A Lacueva, PM Lanuza, ...
Scientific reports 6 (1), 36086, 2016
1252016
Glioblastoma on a microfluidic chip: Generating pseudopalisades and enhancing aggressiveness through blood vessel obstruction events
JM Ayuso, R Monge, A Martínez-González, M Virumbrales-Muñoz, ...
Neuro-oncology 19 (4), 503-513, 2017
1222017
Evaluating natural killer cell cytotoxicity against solid tumors using a microfluidic model
JM Ayuso, R Truttschel, MM Gong, M Humayun, M Virumbrales-Munoz, ...
Oncoimmunology 8 (3), 1553477, 2019
1162019
Microfluidic tumor-on-a-chip model to evaluate the role of tumor environmental stress on NK cell exhaustion
JM Ayuso, S Rehman, M Virumbrales-Munoz, PH McMinn, P Geiger, ...
Science Advances 7 (8), eabc2331, 2021
972021
Tumor-on-a-chip: a microfluidic model to study cell response to environmental gradients
JM Ayuso, M Virumbrales-Munoz, PH McMinn, S Rehman, I Gomez, ...
Lab on a Chip 19 (20), 3461-3471, 2019
832019
Organotypic microfluidic breast cancer model reveals starvation-induced spatial-temporal metabolic adaptations
JM Ayuso, A Gillette, K Lugo-Cintrón, S Acevedo-Acevedo, I Gomez, ...
EBioMedicine 37, 144-157, 2018
812018
A role for microfluidic systems in precision medicine
JM Ayuso, M Virumbrales-Muñoz, JM Lang, DJ Beebe
Nature communications 13 (1), 3086, 2022
782022
Microfluidic lumen-based systems for advancing tubular organ modeling
M Virumbrales-Muñoz, JM Ayuso, MM Gong, M Humayun, MK Livingston, ...
Chemical Society Reviews 49 (17), 6402-6442, 2020
662020
Breast fibroblasts and ECM components modulate breast cancer cell migration through the secretion of MMPs in a 3D microfluidic co-culture model
KM Lugo-Cintron, MM Gong, JM Ayuso, LA Tomko, DJ Beebe, ...
Cancers 12 (5), 1173, 2020
632020
Human tumor‐lymphatic microfluidic model reveals differential conditioning of lymphatic vessels by breast cancer cells
JM Ayuso, MM Gong, MC Skala, PM Harari, DJ Beebe
Advanced healthcare materials 9 (3), 1900925, 2020
552020
Activated human primary NK cells efficiently kill colorectal cancer cells in 3D spheroid cultures irrespectively of the level of PD-L1 expression
PM Lanuza, A Vigueras, S Olivan, AC Prats, S Costas, G Llamazares, ...
Oncoimmunology 7 (4), e1395123, 2018
522018
High-order TRAIL oligomer formation in TRAIL-coated lipid nanoparticles enhances DR5 cross-linking and increases antitumour effect against colon cancer
D De Miguel, A Gallego-Lleyda, JM Ayuso, D Pejenaute-Ochoa, V Jarauta, ...
Cancer letters 383 (2), 250-260, 2016
522016
Matrix density drives 3D organotypic lymphatic vessel activation in a microfluidic model of the breast tumor microenvironment
KM Lugo-Cintrón, JM Ayuso, BR White, PM Harari, SM Ponik, DJ Beebe, ...
Lab on a Chip 20 (9), 1586-1600, 2020
462020
Tau protein provides DNA with thermodynamic and structural features which are similar to those found in histone-DNA complex
S Camero, MJ Benítez, A Barrantes, JM Ayuso, R Cuadros, J Avila, ...
Journal of Alzheimer's Disease 39 (3), 649-660, 2014
462014
TRAIL-coated lipid-nanoparticles overcome resistance to soluble recombinant TRAIL in non-small cell lung cancer cells
D De Miguel, A Gallego-Lleyda, JM Ayuso, S Erviti-Ardanaz, R Pazo-Cid, ...
Nanotechnology 27 (18), 185101, 2016
432016
Study of the chemotactic response of multicellular spheroids in a microfluidic device
JM Ayuso, HA Basheer, R Monge, P Sánchez-Álvarez, M Doblaré, ...
PloS one 10 (10), e0139515, 2015
422015
Enabling cell recovery from 3D cell culture microfluidic devices for tumour microenvironment biomarker profiling
M Virumbrales-Muñoz, JM Ayuso, A Lacueva, T Randelovic, ...
Scientific Reports 9 (1), 6199, 2019
382019
Multiwell capillarity-based microfluidic device for the study of 3D tumour tissue-2D endothelium interactions and drug screening in co-culture models
M Virumbrales-Muñoz, JM Ayuso, M Olave, R Monge, D de Miguel, ...
Scientific reports 7 (1), 11998, 2017
372017
Toward improved in vitro models of human cancer
JM Ayuso, KY Park, M Virumbrales-Muñoz, DJ Beebe
APL bioengineering 5 (1), 2021
342021
Agarose Spot as a Comparative Method for in situ Analysis of Simultaneous Chemotactic Responses to Multiple Chemokines
M Ahmed, HA Basheer, JM Ayuso, D Ahmet, M Mazzini, R Patel, ...
Scientific reports 7 (1), 1075, 2017
342017
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