Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells J Hsieh, K Nakashima, T Kuwabara, E Mejia, FH Gage Proceedings of the National Academy of Sciences 101 (47), 16659-16664, 2004 | 814 | 2004 |
Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis T Kuwabara, J Hsieh, A Muotri, G Yeo, M Warashina, DC Lie, L Moore, ... Nature neuroscience 12 (9), 1097-1105, 2009 | 741 | 2009 |
A small modulatory dsRNA specifies the fate of adult neural stem cells T Kuwabara, J Hsieh, K Nakashima, K Taira, FH Gage Cell 116 (6), 779-793, 2004 | 568 | 2004 |
Noncoding RNAs in the mammalian central nervous system X Cao, G Yeo, AR Muotri, T Kuwabara, FH Gage Annu. Rev. Neurosci. 29, 77-103, 2006 | 557 | 2006 |
IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes J Hsieh, JB Aimone, BK Kaspar, T Kuwabara, K Nakashima, FH Gage The Journal of cell biology 164 (1), 111-122, 2004 | 413 | 2004 |
Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation BZ Barkho, H Song, JB Aimone, RD Smrt, T Kuwabara, K Nakashima, ... Stem cells and development 15 (3), 407-421, 2006 | 389 | 2006 |
A novel allosterically trans-activated ribozyme, the maxizyme, with exceptional specificity in vitro and in vivo T Kuwabara, M Warashina, T Tanabe, K Tani, S Asano, K Taira Molecular Cell 2 (5), 617-627, 1998 | 205 | 1998 |
Reduction in paracrine Wnt3 factors during aging causes impaired adult neurogenesis M Okamoto, K Inoue, H Iwamura, K Terashima, H Soya, M Asashima, ... The FASEB Journal 25 (10), 3570-3582, 2011 | 171 | 2011 |
Insulin biosynthesis in neuronal progenitors derived from adult hippocampus and the olfactory bulb T Kuwabara, MN Kagalwala, Y Onuma, Y Ito, M Warashina, K Terashima, ... EMBO molecular medicine 3 (12), 742-754, 2011 | 148 | 2011 |
Extremely high and specific activity of DNA enzymes in cells with a Philadelphia chromosome M Warashina, T Kuwabara, Y Nakamatsu, K Taira Chemistry & biology 6 (4), 237-250, 1999 | 127 | 1999 |
RNA–protein hybrid ribozymes that efficiently cleave any mRNA independently of the structure of the target RNA M Warashina, T Kuwabara, Y Kato, M Sano, K Taira Proceedings of the National Academy of Sciences 98 (10), 5572-5577, 2001 | 125 | 2001 |
Relationships between the activities in vitro and in vivo of various kinds of ribozyme and their intracellular localization in mammalian cells Y Kato, T Kuwabara, M Warashina, H Toda, K Taira Journal of Biological Chemistry 276 (18), 15378-15385, 2001 | 124 | 2001 |
Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells X Li, BZ Barkho, Y Luo, RD Smrt, NJ Santistevan, C Liu, T Kuwabara, ... Journal of Biological Chemistry 283 (41), 27644-27652, 2008 | 120 | 2008 |
A synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells M Warashina, KH Min, T Kuwabara, A Huynh, FH Gage, PG Schultz, ... Angewandte Chemie 118 (4), 605-607, 2006 | 110 | 2006 |
Oncogene inactivation in a mouse model T Tanabe, T Kuwabara, M Warashina, K Tani, K Taira, S Asano Nature 406 (6795), 473-474, 2000 | 108 | 2000 |
Wnt protein-mediated satellite cell conversion in adult and aged mice following voluntary wheel running S Fujimaki, R Hidaka, M Asashima, T Takemasa, T Kuwabara Journal of biological chemistry 289 (11), 7399-7412, 2014 | 104 | 2014 |
tRNAVal-heterodimeric maxizymes with high potential as geneinactivating agents: Simultaneous cleavage at two sites in HIV-1 tat mRNA in cultured cells T Kuwabara, M Warashina, A Nakayama, J Ohkawa, K Taira Proceedings of the National Academy of Sciences 96 (5), 1886-1891, 1999 | 99 | 1999 |
Formation of a catalytically active dimer by tRNAVal -driven short ribozymes T Kuwabara, M Warashina, M Orita, S Koseki, J Ohkawa, K Taira Nature biotechnology 16 (10), 961-965, 1998 | 98 | 1998 |
Comparison of the specificities and catalytic activities of hammerhead ribozymes and DNA enzymes with respect to the cleavage of BCR-ABL chimeric L6 (b2a2) mRNA T Kuwabara, M Warashina, T Tanabe, K Tani, S Asano, K Taira Nucleic acids research 25 (15), 3074-3081, 1997 | 97 | 1997 |
Diabetes-induced dysfunction of mitochondria and stem cells in skeletal muscle and the nervous system S Fujimaki, T Kuwabara International Journal of Molecular Sciences 18 (10), 2147, 2017 | 83 | 2017 |