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Ved Topkar
Ved Topkar
Stanford Medical School, Harvard College
Подтвержден адрес электронной почты в домене stanford.edu - Главная страница
Название
Процитировано
Процитировано
Год
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
SQ Tsai, Z Zheng, NT Nguyen, M Liebers, VV Topkar, V Thapar, ...
Nature Biotechnology, 2014
22602014
Engineered CRISPR-Cas9 nucleases with altered PAM specificities
BP Kleinstiver, MS Prew, SQ Tsai, VV Topkar, NT Nguyen, Z Zheng, ...
Nature 523 (7561), 481-485, 2015
18682015
CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR–Cas9 nuclease off-targets
SQ Tsai, NT Nguyen, J Malagon-Lopez, VV Topkar, MJ Aryee, JK Joung
Nature methods 14 (6), 607-614, 2017
7182017
Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition
BP Kleinstiver, MS Prew, SQ Tsai, NT Nguyen, VV Topkar, Z Zheng, ...
Nature biotechnology 33 (12), 1293-1298, 2015
7052015
Dimeric CRISPR RNA-guided FokI-dCas9 nucleases directed by truncated gRNAs for highly specific genome editing
N Wyvekens, VV Topkar, C Khayter, JK Joung, SQ Tsai
Human gene therapy 26 (7), 425-431, 2015
1932015
Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures
K Kappel, K Zhang, Z Su, AM Watkins, W Kladwang, S Li, G Pintilie, ...
Nature methods 17 (7), 699-707, 2020
1372020
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics
K Leppek, GW Byeon, W Kladwang, HK Wayment-Steele, CH Kerr, AF Xu, ...
Nature communications 13 (1), 1536, 2022
1282022
Replacing uridine with 2-thiouridine enhances the rate and fidelity of nonenzymatic RNA primer extension
BD Heuberger, A Pal, F Del Frate, VV Topkar, JW Szostak
Journal of the American Chemical Society 137 (7), 2769-2775, 2015
762015
Open-source guideseq software for analysis of GUIDE-seq data
SQ Tsai, VV Topkar, JK Joung, MJ Aryee
Nature Biotechnology 34 (5), 483-483, 2016
752016
Defining genome-wide CRISPR–Cas genome-editing nuclease activity with GUIDE-seq
NL Malinin, GH Lee, CR Lazzarotto, Y Li, Z Zheng, NT Nguyen, M Liebers, ...
Nature protocols 16 (12), 5592-5615, 2021
352021
Transcription factors, coregulators, and epigenetic marks are linearly correlated and highly redundant
T Ahsendorf, FJ Müller, V Topkar, J Gunawardena, R Eils
PLoS One 12 (12), e0186324, 2017
172017
mRNA transport and local translation in glia
LM Meservey, VV Topkar, M Fu
Trends in cell biology 31 (6), 419-423, 2021
142021
Three-dimensional structure-guided evolution of a ribosome with tethered subunits
DS Kim, A Watkins, E Bidstrup, J Lee, V Topkar, C Kofman, KJ Schwarz, ...
Nature chemical biology 18 (9), 990-998, 2022
112022
Anomalous reverse transcription through chemical modifications in polyadenosine stretches
W Kladwang, VV Topkar, B Liu, R Rangan, TL Hodges, SC Keane, ...
Biochemistry 59 (23), 2154-2170, 2020
102020
Structural Determinants of MRNA Transport Specificity in Oligodendrocytes
VV Topkar
Biophysical Journal 118 (3), 67a, 2020
2020
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