The clonal and mutational evolution spectrum of primary triple-negative breast cancers SP Shah, A Roth, R Goya, A Oloumi, G Ha, Y Zhao, G Turashvili, J Ding, ... Nature 486 (7403), 395-399, 2012 | 2336 | 2012 |
PyClone: statistical inference of clonal population structure in cancer A Roth, J Khattra, D Yap, A Wan, E Laks, J Biele, G Ha, S Aparicio, ... Nature methods 11 (4), 396-398, 2014 | 1014 | 2014 |
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution P Eirew, A Steif, J Khattra, G Ha, D Yap, H Farahani, K Gelmon, S Chia, ... Nature 518 (7539), 422-426, 2015 | 673 | 2015 |
Recurrent Somatic DICER1 Mutations in Nonepithelial Ovarian Cancers A Heravi-Moussavi, MS Anglesio, SWG Cheng, J Senz, W Yang, ... New England Journal of Medicine 366 (3), 234-242, 2012 | 535 | 2012 |
Distinct evolutionary trajectories of primary high‐grade serous ovarian cancers revealed through spatial mutational profiling A Bashashati, G Ha, A Tone, J Ding, LM Prentice, A Roth, J Rosner, ... The Journal of pathology 231 (1), 21-34, 2013 | 509 | 2013 |
Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing RD Morin, K Mungall, E Pleasance, AJ Mungall, R Goya, RD Huff, ... Blood, The Journal of the American Society of Hematology 122 (7), 1256-1265, 2013 | 471 | 2013 |
TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data G Ha, A Roth, J Khattra, J Ho, D Yap, LM Prentice, N Melnyk, ... Genome research 24 (11), 1881-1893, 2014 | 418 | 2014 |
Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer A McPherson, A Roth, E Laks, T Masud, A Bashashati, AW Zhang, G Ha, ... Nature genetics 48 (7), 758-767, 2016 | 364 | 2016 |
Divergent clonal selection dominates medulloblastoma at recurrence AS Morrissy, L Garzia, DJH Shih, S Zuyderduyn, X Huang, P Skowron, ... Nature 529 (7586), 351-357, 2016 | 355 | 2016 |
Interfaces of malignant and immunologic clonal dynamics in ovarian cancer AW Zhang, A McPherson, K Milne, DR Kroeger, PT Hamilton, A Miranda, ... Cell 173 (7), 1755-1769. e22, 2018 | 330 | 2018 |
Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer G Ha, A Roth, D Lai, A Bashashati, J Ding, R Goya, R Giuliany, J Rosner, ... Genome research 22 (10), 1995-2007, 2012 | 320 | 2012 |
Histological transformation and progression in follicular lymphoma: a clonal evolution study R Kridel, FC Chan, A Mottok, M Boyle, P Farinha, K Tan, B Meissner, ... PLoS medicine 13 (12), e1002197, 2016 | 250 | 2016 |
JointSNVMix: a probabilistic model for accurate detection of somatic mutations in normal/tumour paired next-generation sequencing data A Roth, J Ding, R Morin, A Crisan, G Ha, R Giuliany, A Bashashati, M Hirst, ... Bioinformatics 28 (7), 907-913, 2012 | 236 | 2012 |
Feature-based classifiers for somatic mutation detection in tumour–normal paired sequencing data J Ding, A Bashashati, A Roth, A Oloumi, K Tse, T Zeng, G Haffari, M Hirst, ... Bioinformatics 28 (2), 167-175, 2012 | 199 | 2012 |
Mutational context and diverse clonal development in early and late bladder cancer I Nordentoft, P Lamy, K Birkenkamp-Demtröder, K Shumansky, S Vang, ... Cell reports 7 (5), 1649-1663, 2014 | 173 | 2014 |
Clonal genotype and population structure inference from single-cell tumor sequencing A Roth, A McPherson, E Laks, J Biele, D Yap, A Wan, MA Smith, ... Nature methods 13 (7), 573-576, 2016 | 128 | 2016 |
PyClone-VI: scalable inference of clonal population structures using whole genome data S Gillis, A Roth BMC bioinformatics 21, 1-16, 2020 | 99 | 2020 |
ddClone: joint statistical inference of clonal populations from single cell and bulk tumour sequencing data S Salehi, A Steif, A Roth, S Aparicio, A Bouchard-Côté, SP Shah Genome biology 18, 1-18, 2017 | 62 | 2017 |
E-scape: interactive visualization of single-cell phylogenetics and cancer evolution MA Smith, CB Nielsen, FC Chan, A McPherson, A Roth, H Farahani, ... Nature methods 14 (6), 549-550, 2017 | 49 | 2017 |
Single cell transcriptomes of normal endometrial derived organoids uncover novel cell type markers and cryptic differentiation of primary tumours DR Cochrane, KR Campbell, K Greening, GC Ho, J Hopkins, M Bui, ... The Journal of Pathology 252 (2), 201-214, 2020 | 48 | 2020 |