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Takaharu Ichimura Ph.D.
Takaharu Ichimura Ph.D.
brigham & women's hospital
Verified email at bwh.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury
T Ichimura, JV Bonventre, V Bailly, H Wei, CA Hession, RL Cate, ...
Journal of Biological Chemistry 273 (7), 4135-4142, 1998
16401998
Urinary kidney injury molecule-1: a sensitive quantitative biomarker for early detection of kidney tubular injury
VS Vaidya, V Ramirez, T Ichimura, NA Bobadilla, JV Bonventre
American Journal of Physiology-Renal Physiology 290 (2), F517-F529, 2006
9602006
Kidney injury molecule–1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells
T Ichimura, EJP Asseldonk, BD Humphreys, L Gunaratnam, JS Duffield, ...
The Journal of clinical investigation 118 (5), 1657-1668, 2008
9272008
Kidney injury molecule-1: a tissue and urinary biomarker for nephrotoxicant-induced renal injury
T Ichimura, CC Hung, SA Yang, JL Stevens, JV Bonventre
American Journal of Physiology-Renal Physiology 286 (3), F552-F563, 2004
8712004
Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells
JS Duffield, KM Park, LL Hsiao, VR Kelley, DT Scadden, T Ichimura, ...
The Journal of clinical investigation 115 (7), 1743-1755, 2005
7252005
Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis
I Grgic, G Campanholle, V Bijol, C Wang, VS Sabbisetti, T Ichimura, ...
Kidney international 82 (2), 172-183, 2012
4762012
Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis
BD Humphreys, F Xu, V Sabbisetti, I Grgic, SM Naini, N Wang, G Chen, ...
The Journal of clinical investigation 123 (9), 4023-4035, 2013
3882013
KIM-1–mediated phagocytosis reduces acute injury to the kidney
L Yang, CR Brooks, S Xiao, V Sabbisetti, MY Yeung, LL Hsiao, T Ichimura, ...
The Journal of clinical investigation 125 (4), 1620-1636, 2015
3342015
Protection of renal epithelial cells against oxidative injury by endoplasmic reticulum stress preconditioning is mediated by ERK1/2 activation
CC Hung, T Ichimura, JL Stevens, JV Bonventre
Journal of Biological Chemistry 278 (31), 29317-29326, 2003
2592003
Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway
Y Tong, E Giaime, H Yamaguchi, T Ichimura, Y Liu, H Si, H Cai, ...
Molecular neurodegeneration 7, 1-16, 2012
2502012
Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice
S Xiao, CR Brooks, C Zhu, C Wu, JM Sweere, S Petecka, A Yeste, ...
Proceedings of the National Academy of Sciences 109 (30), 12105-12110, 2012
1542012
KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease
Y Mori, AK Ajay, JH Chang, S Mou, H Zhao, S Kishi, J Li, CR Brooks, ...
Cell metabolism 33 (5), 1042-1061. e7, 2021
1252021
Cyclin G1 and TASCC regulate kidney epithelial cell G2-M arrest and fibrotic maladaptive repair
G Canaud, CR Brooks, S Kishi, K Taguchi, K Nishimura, S Magassa, ...
Science translational medicine 11 (476), eaav4754, 2019
1122019
Conformational change in transfer RNA is an early indicator of acute cellular damage
E Mishima, C Inoue, D Saigusa, R Inoue, K Ito, Y Suzuki, D Jinno, ...
Journal of the American Society of Nephrology 25 (10), 2316-2326, 2014
1042014
Polylactide-cyclosporin A nanoparticles for targeted immunosuppression
J Azzi, L Tang, R Moore, R Tong, N El Haddad, T Akiyoshi, B Mfarrej, ...
The FASEB Journal 24 (10), 3927, 2010
1042010
KIM‐1‐/TIM‐1‐mediated phagocytosis links ATG 5‐/ULK 1‐dependent clearance of apoptotic cells to antigen presentation
CR Brooks, MY Yeung, YS Brooks, H Chen, T Ichimura, JM Henderson, ...
The EMBO journal 34 (19), 2441-2464, 2015
1022015
Kim-1/Tim-1 and immune cells: shifting sands
T Ichimura, CR Brooks, JV Bonventre
Kidney international 81 (9), 809-811, 2012
1022012
Targeted delivery of immunomodulators to lymph nodes
J Azzi, Q Yin, M Uehara, S Ohori, L Tang, K Cai, T Ichimura, M McGrath, ...
Cell reports 15 (6), 1202-1213, 2016
952016
Urinary kidney injury molecule-1 and monocyte chemotactic protein-1 are noninvasive biomarkers of cisplatin-induced nephrotoxicity in lung cancer patients
H Shinke, S Masuda, Y Togashi, Y Ikemi, A Ozawa, T Sato, YH Kim, ...
Cancer chemotherapy and pharmacology 76, 989-996, 2015
942015
T cell, Ig domain, mucin domain-2 gene-deficient mice reveal a novel mechanism for the regulation of Th2 immune responses and airway inflammation
PD Rennert, T Ichimura, ID Sizing, V Bailly, Z Li, R Rennard, P McCoon, ...
The Journal of Immunology 177 (7), 4311-4321, 2006
882006
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