| Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing H Yin, CQ Song, S Suresh, Q Wu, S Walsh, LH Rhym, E Mintzer, ... Nature biotechnology 35 (12), 1179-1187, 2017 | 471 | 2017 |
| Adenine base editing in an adult mouse model of tyrosinaemia CQ Song, T Jiang, M Richter, LH Rhym, LW Koblan, MP Zafra, ... Nature biomedical engineering 4 (1), 125-130, 2020 | 160 | 2020 |
| Reduction of the therapeutic dose of silencing RNA by packaging it in extracellular vesicles via a pre-microRNA backbone R Reshke, JA Taylor, A Savard, H Guo, LH Rhym, PS Kowalski, MT Trung, ... Nature biomedical engineering 4 (1), 52-68, 2020 | 113 | 2020 |
| Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope T Jiang, JM Henderson, K Coote, Y Cheng, HC Valley, XO Zhang, ... Nature communications 11 (1), 1979, 2020 | 94 | 2020 |
| Customizable lipid nanoparticle materials for the delivery of siRNAs and mRNAs OS Fenton, KJ Kauffman, RL McClellan, JC Kaczmarek, MD Zeng, ... Angewandte Chemie International Edition 57 (41), 13582-13586, 2018 | 74 | 2018 |
| Systemic delivery of mRNA and DNA to the lung using polymer-lipid nanoparticles JC Kaczmarek, AK Patel, LH Rhym, UC Palmiero, B Bhat, MW Heartlein, ... Biomaterials 275, 120966, 2021 | 67 | 2021 |
| Peptide-encoding mRNA barcodes for the high-throughput in vivo screening of libraries of lipid nanoparticles for mRNA delivery LH Rhym, RS Manan, A Koller, G Stephanie, DG Anderson Nature Biomedical Engineering 7 (7), 901-910, 2023 | 25 | 2023 |
| Downregulation of the Arg/N-degron pathway sensitizes cancer cells to chemotherapy in vivo D Leboeuf, T Abakumova, T Prikazchikova, L Rhym, DG Anderson, ... Molecular therapy 28 (4), 1092-1104, 2020 | 23 | 2020 |
| Enhancing the immunogenicity of lipid-nanoparticle mRNA vaccines by adjuvanting the ionizable lipid and the mRNA B Li, AY Jiang, I Raji, C Atyeo, TM Raimondo, AGR Gordon, LH Rhym, ... Nature Biomedical Engineering, 1-18, 2023 | 15 | 2023 |
| Partitioning of coomassie brilliant blue into DMAEMA containing poly (HEMA)-based hydrogels CN Kotanen, DR Janagam, R Idziak, L Rhym, R Sullivan, AM Wilson, ... European Polymer Journal 72, 438-450, 2015 | 15 | 2015 |
| Nanoscale delivery platforms for RNA therapeutics: Challenges and the current state of the art LH Rhym, DG Anderson Med 3 (3), 167-187, 2022 | 13 | 2022 |
| Ionizable lipids and compositions and uses thereof DG Anderson, LH Rhym, A Jiang, J Witten, I Raji US Patent App. 18/080,299, 2023 | | 2023 |
| Polymer-lipids and compositions JC Kaczmarek, DG Anderson, LH Rhym, KJ Kauffman, AK Patel US Patent 11,608,412, 2023 | | 2023 |
| Engineering Dually Adjuvanted Sars-CoV2 mRNA Vaccines A Jiang, B Li, I Raji, C Atyeo, TM Raimondo, A Gordon, L Rhym, G Alter, ... 2022 AIChE Annual Meeting, 2022 | | 2022 |
| Development and applications of peptide barcoded nanoparticles for high-throughput screening of mRNA delivery materials in vivo LH Rhym Massachusetts Institute of Technology, 2022 | | 2022 |
Daniel G. AndersonMassachusetts Institute of TechnologyПодтвержден адрес электронной почты в домене mit.edu
