Studies on the mechanism of hypoxic selectivity in copper bis (thiosemicarbazone) radiopharmaceuticals RI Maurer, PJ Blower, JR Dilworth, CA Reynolds, Y Zheng, GED Mullen Journal of medicinal chemistry 45 (7), 1420-1431, 2002 | 226 | 2002 |
Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor YL Liang, M Khoshouei, G Deganutti, A Glukhova, C Koole, TS Peat, ... Nature 561 (7724), 492-497, 2018 | 206 | 2018 |
Atomic charges for variable molecular conformations CA Reynolds, JW Essex, WG Richards Journal of the American Chemical Society 114 (23), 9075-9079, 1992 | 184 | 1992 |
Dimerization and domain swapping in G-protein-coupled receptors: a computational study PR Gouldson, C Higgs, RE Smith, MK Dean, GV Gkoutos, CA Reynolds Neuropsychopharmacology 23 (4), S60-S77, 2000 | 181 | 2000 |
Semiempirical AM1 electrostatic potentials and AM1 electrostatic potential derived charges: A comparison with ab initio values GG Ferenczy, CA Reynolds, WG Richards Journal of computational chemistry 11 (2), 159-169, 1990 | 172 | 1990 |
Dimerization of G-protein-coupled receptors MK Dean, C Higgs, RE Smith, RP Bywater, CR Snell, PD Scott, ... Journal of medicinal chemistry 44 (26), 4595-4614, 2001 | 171 | 2001 |
Domain swapping in G-protein coupled receptor dimers. PR Gouldson, CR Snell, RP Bywater, C Higgs, CA Reynolds Protein engineering 11 (12), 1181-1193, 1998 | 155 | 1998 |
The extracellular surface of the GLP-1 receptor is a molecular trigger for biased agonism D Wootten, CA Reynolds, KJ Smith, JC Mobarec, C Koole, EE Savage, ... Cell 165 (7), 1632-1643, 2016 | 131 | 2016 |
Towards new transition metal-based hypoxic selective agents for therapy and imaging PJ Blower, JR Dilworth, RI Maurer, GD Mullen, CA Reynolds, Y Zheng Journal of inorganic biochemistry 85 (1), 15-22, 2001 | 114 | 2001 |
Free energy calculations in molecular biophysics CA Reynolds, PM King, WG Richards Molecular Physics 76 (2), 251-275, 1992 | 112 | 1992 |
Computed redox potentials and the design of bioreductive agents CA Reynolds, PM King, WG Richards Nature 334 (6177), 80-82, 1988 | 109 | 1988 |
Toward the active conformations of rhodopsin and the β2‐adrenergic receptor PR Gouldson, NJ Kidley, RP Bywater, G Psaroudakis, HD Brooks, C Diaz, ... Proteins: Structure, Function, and Bioinformatics 56 (1), 67-84, 2004 | 107 | 2004 |
A New Approach to Docking in the β2-Adrenergic Receptor That Exploits the Domain Structure of G-Protein-Coupled Receptors PR Gouldson, CR Snell, CA Reynolds Journal of medicinal chemistry 40 (24), 3871-3886, 1997 | 102 | 1997 |
Activation of the GLP-1 receptor by a non-peptidic agonist P Zhao, YL Liang, MJ Belousoff, G Deganutti, MM Fletcher, FS Willard, ... Nature 577 (7790), 432-436, 2020 | 101 | 2020 |
Theoretical determination of partition coefficients JW Essex, CA Reynolds, WG Richards Journal of the American Chemical Society 114 (10), 3634-3639, 1992 | 87 | 1992 |
Theoretical electrode potentials and conformational energies of benzoquinones and naphthoquinones in aqueous solution CA Reynolds Journal of the American Chemical Society 112 (21), 7545-7551, 1990 | 83 | 1990 |
Receptor activity-modifying protein-directed G protein signaling specificity for the calcitonin gene-related peptide family of receptors C Weston, I Winfield, M Harris, R Hodgson, A Shah, SJ Dowell, ... Journal of Biological Chemistry 291 (42), 21925-21944, 2016 | 82 | 2016 |
Do plants contain g protein-coupled receptors? B Taddese, GJG Upton, GR Bailey, SRD Jordan, NY Abdulla, PJ Reeves, ... Plant physiology 164 (1), 287-307, 2014 | 75 | 2014 |
Criteria for confirming sequence periodicity identified by Fourier transform analysis: application to GCR2, a candidate plant GPCR? CJR Illingworth, KE Parkes, CR Snell, PM Mullineaux, CA Reynolds Biophysical chemistry 133 (1-3), 28-35, 2008 | 71 | 2008 |
Bioinformatics and molecular modelling approaches to GPCR oligomerization LM Simpson, B Taddese, ID Wall, CA Reynolds Current opinion in pharmacology 10 (1), 30-37, 2010 | 70 | 2010 |