| Molecular recognition of parathyroid hormone by its G protein-coupled receptor AA Pioszak, HE Xu Proceedings of the National Academy of Sciences 105 (13), 5034-5039, 2008 | 302 | 2008 |
| Molecular recognition of corticotropin-releasing factor by its G-protein-coupled receptor CRFR1 AA Pioszak, NR Parker, K Suino-Powell, HE Xu Journal of Biological Chemistry 283 (47), 32900-32912, 2008 | 187 | 2008 |
| Receptor activity-modifying proteins (RAMPs): new insights and roles DL Hay, AA Pioszak Annual review of pharmacology and toxicology 56, 469-487, 2016 | 176 | 2016 |
| Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides AA Pioszak, NR Parker, TJ Gardella, HE Xu Journal of biological chemistry 284 (41), 28382-28391, 2009 | 171 | 2009 |
| Structural basis for receptor activity-modifying protein-dependent selective peptide recognition by a G protein-coupled receptor JM Booe, CS Walker, J Barwell, G Kuteyi, J Simms, MA Jamaluddin, ... Molecular cell 58 (6), 1040-1052, 2015 | 126 | 2015 |
| Structural basis for hormone recognition by the Human CRFR2α G protein-coupled receptor K Pal, K Swaminathan, HE Xu, AA Pioszak Journal of biological chemistry 285 (51), 40351-40361, 2010 | 97 | 2010 |
| Crystal structure of the PAC1R extracellular domain unifies a consensus fold for hormone recognition by class B G-protein coupled receptors S Kumar, A Pioszak, C Zhang, K Swaminathan, HE Xu PloS one 6 (5), e19682, 2011 | 91 | 2011 |
| The Escherichia coli PII Signal Transduction Protein Regulates the Activities of the Two-Component System Transmitter Protein NRII by Direct Interaction with the … AA Pioszak, P Jiang, AJ Ninfa Biochemistry 39 (44), 13450-13461, 2000 | 81 | 2000 |
| Calcitonin and amylin receptor peptide interaction mechanisms: insights into peptide-binding modes and allosteric modulation of the calcitonin receptor by receptor activity … SM Lee, DL Hay, AA Pioszak Journal of biological chemistry 291 (16), 8686-8700, 2016 | 78 | 2016 |
| Structural insights into ligand recognition and selectivity for classes A, B, and C GPCRs SM Lee, JM Booe, AA Pioszak European journal of pharmacology 763, 196-205, 2015 | 77 | 2015 |
| Dimeric arrangement of the parathyroid hormone receptor and a structural mechanism for ligand-induced dissociation AA Pioszak, KG Harikumar, NR Parker, LJ Miller, HE Xu Journal of biological chemistry 285 (16), 12435-12444, 2010 | 76 | 2010 |
| Crystal structure of the C-terminal domain of the two-component system transmitter protein nitrogen regulator II (NRII; NtrB), regulator of nitrogen assimilation in Escherichia … Y Song, D Peisach, AA Pioszak, Z Xu, AJ Ninfa Biochemistry 43 (21), 6670-6678, 2004 | 57 | 2004 |
| Molecular signature for receptor engagement in the metabolic peptide hormone amylin RL Bower, L Yule, TA Rees, G Deganutti, ER Hendrikse, PWR Harris, ... ACS Pharmacology & Translational Science 1 (1), 32-49, 2018 | 56 | 2018 |
| An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology J J Gingell, J Simms, J Barwell, DR Poyner, HA Watkins, AA Pioszak, ... Cell discovery 2 (1), 1-14, 2016 | 52 | 2016 |
| Genetic and Biochemical Analysis of Phosphatase Activity of Escherichia coli NRII (NtrB) and Its Regulation by the PII Signal Transduction Protein AA Pioszak, AJ Ninfa Journal of bacteriology 185 (4), 1299-1315, 2003 | 50 | 2003 |
| Receptor activity-modifying proteins 2 and 3 generate adrenomedullin receptor subtypes with distinct molecular properties HA Watkins, M Chakravarthy, RS Abhayawardana, JJ Gingell, M Garelja, ... Journal of Biological Chemistry 291 (22), 11657-11675, 2016 | 47 | 2016 |
| Mutations Altering the N-Terminal Receiver Domain of NRI (NtrC) That Prevent Dephosphorylation by the NRII-PII Complex in Escherichia coli AA Pioszak, AJ Ninfa Journal of bacteriology 186 (17), 5730-5740, 2004 | 47 | 2004 |
| Probing the mechanism of receptor activity–modifying protein modulation of GPCR ligand selectivity through rational design of potent adrenomedullin and calcitonin gene-related … JM Booe, ML Warner, AM Roehrkasse, DL Hay, AA Pioszak Molecular pharmacology 93 (4), 355-367, 2018 | 43 | 2018 |
| Calcitonin receptor N-glycosylation enhances peptide hormone affinity by controlling receptor dynamics SM Lee, Y Jeong, J Simms, ML Warner, DR Poyner, KY Chung, ... Journal of molecular biology 432 (7), 1996-2014, 2020 | 37 | 2020 |
| Selective CGRP and adrenomedullin peptide binding by tethered RAMP‐calcitonin receptor‐like receptor extracellular domain fusion proteins HE Moad, AA Pioszak Protein Science 22 (12), 1775-1785, 2013 | 37 | 2013 |
Debbie L HayDepartment of Pharmacology & Toxicology, University of Otago and School of Biological SciencesVerified email at otago.ac.nz
