Follow
Xue Xia
Xue Xia
Senior Specialist, Merck & Co Inc
Verified email at merck.com
Title
Cited by
Cited by
Year
Pharmacokinetic Properties of 2nd-Generation Fibroblast Growth Factor-1 Mutants for Therapeutic Application
X Xia, JP Babcock, SI Blaber, KM Harper, M Blaber
PLoS one 7 (11), e48210, 2012
502012
Mutation choice to eliminate buried free cysteines in protein therapeutics
X Xia, LM Longo, M Blaber
Journal of pharmaceutical sciences 104 (2), 566-576, 2015
272015
Evolution of a protein folding nucleus
X Xia, LM Longo, MA Sutherland, M Blaber
Protein Science 25 (7), 1227-1240, 2016
232016
Engineering a cysteine-free form of human fibroblast growth factor-1 for “second generation” therapeutic application
X Xia, OS Kumru, SI Blaber, CR Middaugh, L Li, DM Ornitz, ...
Journal of pharmaceutical sciences 105 (4), 1444-1453, 2016
192016
Fibroblast growth factor (fgf) 1 with mutation in the heparin binding domain and methods of use to reduce blood glucose
RM Evans, M Downes, A Atkins, TY Ruth, M Blaber, X Xia
US Patent App. 15/681,674, 2017
52017
An S116R phosphorylation site mutation in human fibroblast growth factor-1 differentially affects mitogenic and glucose-lowering activities
X Xia, OS Kumru, SI Blaber, CR Middaugh, L Li, DM Ornitz, JM Suh, ...
Journal of pharmaceutical sciences 105 (12), 3507-3519, 2016
32016
Fibroblast growth factor (fgf) 1 with mutation in the heparin binding domain and methods of use to reduce blood glucose
RM Evans, M Downes, A Atkins, TY Ruth, M Blaber, X Xia
US Patent App. 16/662,553, 2020
12020
Modified fibroblast growth factor 1 (fgf-1) polypeptides with increased binding affinity for heparin and associated methods
M Blaber, X Xia
US Patent App. 17/010,364, 2021
2021
Modified fibroblast growth factor 1 (fgf-1) polypeptides with increased binding affinity for heparin and associated methods
M Blaber, X Xia
US Patent App. 15/532,843, 2018
2018
S116R Phosphorylation Site Mutation in Human FGF-1 Differentially Affects Mitogenic and Glucose Lowering Activities
X Xia, O Kumru, S Blaber, R Middaugh, L Li, D Ornitz, JM Suh, A Atkins, ...
Journal of Pharmaceutical Sciences, 2016
2016
Engineered FGF-1 derivatives stimulate proliferation of corneal endothelial cells
D Eveleth, X Xia, K Thomas, M Blaber
Investigative Ophthalmology & Visual Science 56 (7), 1169-1169, 2015
2015
The system can't perform the operation now. Try again later.
Articles 1–11