Pharmacokinetic Properties of 2nd-Generation Fibroblast Growth Factor-1 Mutants for Therapeutic Application X Xia, JP Babcock, SI Blaber, KM Harper, M Blaber PLoS one 7 (11), e48210, 2012 | 50 | 2012 |
Mutation choice to eliminate buried free cysteines in protein therapeutics X Xia, LM Longo, M Blaber Journal of pharmaceutical sciences 104 (2), 566-576, 2015 | 27 | 2015 |
Evolution of a protein folding nucleus X Xia, LM Longo, MA Sutherland, M Blaber Protein Science 25 (7), 1227-1240, 2016 | 23 | 2016 |
Engineering a cysteine-free form of human fibroblast growth factor-1 for “second generation” therapeutic application X Xia, OS Kumru, SI Blaber, CR Middaugh, L Li, DM Ornitz, ... Journal of pharmaceutical sciences 105 (4), 1444-1453, 2016 | 19 | 2016 |
Fibroblast growth factor (fgf) 1 with mutation in the heparin binding domain and methods of use to reduce blood glucose RM Evans, M Downes, A Atkins, TY Ruth, M Blaber, X Xia US Patent App. 15/681,674, 2017 | 5 | 2017 |
An S116R phosphorylation site mutation in human fibroblast growth factor-1 differentially affects mitogenic and glucose-lowering activities X Xia, OS Kumru, SI Blaber, CR Middaugh, L Li, DM Ornitz, JM Suh, ... Journal of pharmaceutical sciences 105 (12), 3507-3519, 2016 | 3 | 2016 |
Fibroblast growth factor (fgf) 1 with mutation in the heparin binding domain and methods of use to reduce blood glucose RM Evans, M Downes, A Atkins, TY Ruth, M Blaber, X Xia US Patent App. 16/662,553, 2020 | 1 | 2020 |
Modified fibroblast growth factor 1 (fgf-1) polypeptides with increased binding affinity for heparin and associated methods M Blaber, X Xia US Patent App. 17/010,364, 2021 | | 2021 |
Modified fibroblast growth factor 1 (fgf-1) polypeptides with increased binding affinity for heparin and associated methods M Blaber, X Xia US Patent App. 15/532,843, 2018 | | 2018 |
S116R Phosphorylation Site Mutation in Human FGF-1 Differentially Affects Mitogenic and Glucose Lowering Activities X Xia, O Kumru, S Blaber, R Middaugh, L Li, D Ornitz, JM Suh, A Atkins, ... Journal of Pharmaceutical Sciences, 2016 | | 2016 |
Engineered FGF-1 derivatives stimulate proliferation of corneal endothelial cells D Eveleth, X Xia, K Thomas, M Blaber Investigative Ophthalmology & Visual Science 56 (7), 1169-1169, 2015 | | 2015 |