Anastassis Perrakis

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Victor LamzinEuropean Molecular Biology LaboratoryVerified email at embl-hamburg.de
Robbie P. JoostenNetherlands Cancer InstituteVerified email at nki.nl
Titia K. SixmaDivision of Biochemistry, Netherlands Cancer Institute, AmsterdamVerified email at nki.nl
Garib N MurshudovGroup Leader, MRC Laboratory of Molecular BiologyVerified email at mrc-lmb.cam.ac.uk
Alexander FishResercher, Netherlands Cancer InstituteVerified email at nki.nl
Patrick CelieProtein Facility Manager at The Netherlands cancer Institute (NKI)Verified email at nki.nl
Paul EmsleyMRC Laboratory of Molecular BiologyVerified email at mrc-lmb.cam.ac.uk
huib ovaalumc and leiden universityVerified email at lumc.nl
Jens HausmannUniversity of OldenburgVerified email at uni-oldenburg.de
Thijn BrummelkampGroupleader, Netherlands Cancer InstituteVerified email at nki.nl
Joel SussmanWeizmann Institute of ScienceVerified email at weizmann.ac.il
Geert J.P.L. KopsHubrecht InstituteVerified email at hubrecht.eu
Dr Ivo TewsLecturer in Structural Biology, University of SouthamptonVerified email at soton.ac.uk
Dene LittlerMonash UniversityVerified email at monash.edu
Elisa Matas-RicoUniversity of Malaga/ The Biomedical Research Institute of Málaga (IBIMA)Verified email at uma.es
Yoshitaka HirumaJohnson & JohnsonVerified email at its.jnj.com
Krissinel, E*Science and Technology Facilities Council UKVerified email at stfc.ac.uk
Joppe NieuwenhuisPrevious: Netherlands Cancer InstituteVerified email at nki.nl
Marcellus UbbinkProfessor of Protein Chemistry, Leiden UniversityVerified email at chem.leidenuniv.nl
Zoi LygerouProfessor, Medical School, University of Patras, GreeceVerified email at upatras.gr

Anastassis Perrakis

Division of Biochemistry, Netherlands Cancer Institute and Oncode Institute, Prof Utrecht U

Verified email at nki.nl - Homepage

Structural Biology Macromolecular Crystallography Biophysics


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Automated protein model building combined with iterative structure refinement A Perrakis, R Morris, VS Lamzin Nature structural biology 6 (5), 458-463, 1999	3166	1999
Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7 G Langer, SX Cohen, VS Lamzin, A Perrakis Nature protocols 3 (7), 1171-1179, 2008	1877	2008
RNA-binding protein Dnd1 inhibits microRNA access to target mRNA M Kedde, MJ Strasser, B Boldajipour, JAFO Vrielink, K Slanchev, ... Cell 131 (7), 1273-1286, 2007	890	2007
The PDB_REDO server for macromolecular structure model optimization RP Joosten, F Long, GN Murshudov, A Perrakis IUCrJ 1 (4), 213-220, 2014	850	2014
The crystal structure of DNA mismatch repair protein MutS binding to a G· T mismatch MH Lamers, A Perrakis, JH Enzlin, HHK Winterwerp, N De Wind, ... Nature 407 (6805), 711-717, 2000	797	2000
Developments in the CCP4 molecular-graphics project L Potterton, S McNicholas, E Krissinel, J Gruber, K Cowtan, P Emsley, ... Acta Crystallographica Section D: Biological Crystallography 60 (12), 2288-2294, 2004	717	2004
wARP: improvement and extension of crystallographic phases by weighted averaging of multiple-refined dummy atomic models A Perrakis, TK Sixma, KS Wilson, VS Lamzin Acta Crystallographica Section D: Biological Crystallography 53 (4), 448-455, 1997	646	1997
ARP⧸ wARP and automatic interpretation of protein electron density maps RJ Morris, A Perrakis, VS Lamzin Methods in enzymology 374, 229-244, 2003	613	2003
ARP/wARP and molecular replacement A Perrakis, M Harkiolaki, KS Wilson, VS Lamzin Acta Crystallographica Section D: Biological Crystallography 57 (10), 1445-1450, 2001	599	2001
Crystal structure of a bacterial chitinase at 2.3 Å resolution A Perrakis, I Tews, Z Dauter, AB Oppenheim, I Chet, KS Wilson, ... Structure 2 (12), 1169-1180, 1994	525	1994
A new generation of crystallographic validation tools for the protein data bank RJ Read, PD Adams, WB Arendall, AT Brunger, P Emsley, RP Joosten, ... Structure 19 (10), 1395-1412, 2011	511	2011
Structure and E3‐ligase activity of the Ring–Ring complex of Polycomb proteins Bmi1 and Ring1b G Buchwald, P van der Stoop, O Weichenrieder, A Perrakis, ... The EMBO journal 25 (11), 2465-2474, 2006	507	2006
Bacterial chitobiase structure provides insight into catalytic mechanism and the basis of Tay–Sachs disease I Tews, A Perrakis, A Oppenheim, Z Dauter, KS Wilson, CE Vorgias Nature structural biology 3 (7), 638-648, 1996	451	1996
Structure of a cephalosporin synthase K Valegård, ACT Van Scheltinga, MD Lloyd, T Hara, S Ramaswamy, ... Nature 394 (6695), 805-809, 1998	417	1998
Substrate-assisted catalysis unifies two families of chitinolytic enzymes I Tews, AC Terwisscha van Scheltinga, A Perrakis, KS Wilson, BW Dijkstra Journal of the American Chemical Society 119 (34), 7954-7959, 1997	372	1997
Structural basis of substrate discrimination and integrin binding by autotaxin J Hausmann, S Kamtekar, E Christodoulou, JE Day, T Wu, Z Fulkerson, ... Nature structural & molecular biology 18 (2), 198-204, 2011	339	2011
AlphaFill: enriching AlphaFold models with ligands and cofactors ML Hekkelman, I de Vries, RP Joosten, A Perrakis Nature Methods 20 (2), 205-213, 2023	331	2023
Towards rationalization of crystallization screening for small-to medium-sized academic laboratories: the PACT/JCSG+ strategy J Newman, D Egan, TS Walter, R Meged, I Berry, M Ben Jelloul, ... Acta Crystallographica Section D: Biological Crystallography 61 (10), 1426-1431, 2005	322	2005
The CCP4 suite: integrative software for macromolecular crystallography J Agirre, M Atanasova, H Bagdonas, CB Ballard, A Baslé, ... Acta Crystallographica Section D: Structural Biology 79 (6), 449-461, 2023	319	2023
ARP/wARP's model-building algorithms. I. The main chain RJ Morris, A Perrakis, VS Lamzin Acta Crystallographica Section D: Biological Crystallography 58 (6), 968-975, 2002	309	2002

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