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Cullen Myers
Cullen Myers
Assistant Professor, Molecular and Cellular Biology, University of Guelph
Подтвержден адрес электронной почты в домене uoguelph.ca
Название
Процитировано
Процитировано
Год
VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-β-Lactamases, Restores Activity of Cefepime in Enterobacterales and …
JC Hamrick, JD Docquier, T Uehara, CL Myers, DA Six, CL Chatwin, ...
Antimicrobial Agents and Chemotherapy 64 (3), 10.1128/aac. 01963-19, 2020
1772020
Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase
MA Farha, TL Czarny, CL Myers, LJ Worrall, S French, DG Conrady, ...
Proceedings of the National Academy of Sciences 112 (35), 11048-11053, 2015
1122015
Identification of two phosphate starvation-induced wall teichoic acid hydrolases provides first insights into the degradative pathway of a key bacterial cell wall component
CL Myers, FKK Li, BM Koo, OM El-Halfawy, S French, CA Gross, ...
Journal of Biological Chemistry 291 (50), 26066-26082, 2016
452016
Semi-synthetic analogues of thiostrepton delimit the critical nature of tail region modifications in the control of protein biosynthesis and antibacterial activity
CL Myers, PC Hang, G Ng, J Yuen, JF Honek
Bioorganic & medicinal chemistry 18 (12), 4231-4237, 2010
422010
Microbiological characterization of VNRX-5236, a broad-spectrum β-lactamase inhibitor for rescue of the orally bioavailable cephalosporin ceftibuten as a carbapenem-sparing …
CL Chatwin, JC Hamrick, REL Trout, CL Myers, SM Cusick, WJ Weiss, ...
Antimicrobial Agents and Chemotherapy 65 (8), 10.1128/aac. 00552-21, 2021
222021
Characterization of wall teichoic acid degradation by the bacteriophage ϕ29 appendage protein GP12 using synthetic substrate analogs
CL Myers, RG Ireland, TA Garrett, ED Brown
Journal of Biological Chemistry 290 (31), 19133-19145, 2015
182015
Penicillin-binding protein inhibitors
J Burns, D Daigle, GH Chu, J Hamrick, M Lucas, SA Boyd, AL Zulli, ...
WO2018218190, November 29, 2018
142018
Molecular Interactions between Thiostrepton and the TipAS Protein from Streptomyces lividans
CL Myers, J Harris, JCK Yeung, JF Honek
ChemBioChem 15 (5), 681-687, 2014
122014
A cell-based approach to characterize antimicrobial compounds through kinetic dose response
CR MacNair, JM Stokes, S French, CL Myers, KR Iyer, ED Brown
Bioorganic & Medicinal Chemistry 24 (24), 6315-6319, 2016
92016
Ceftibuten/VNRX-7145, an orally bioavailable β-lactam/β-lactamase inhibitor combination active against serine-β-lactamase-producing Enterobacteriaceae
CL Myers, DM Daigle, CJ Burns, DC Pevear
Proceedings of the ECCMID, 2019
52019
Penicillin-binding protein inhibitors
CJ Burns, D Daigle, GH Chu, J Hamrick, M Lucas, SA Boyd, AL Zulli, ...
US Patent 11,332,485, 2022
42022
Penicillin-binding protein inhibitors
CJ Burns, D Daigle, GH Chu, J Hamrick, SA Boyd, AL Zulli, EF Mesaros, ...
US Patent App. 17/057,593, 2021
32021
Functional roles in S-adenosyl-L-methionine binding and catalysis for active site residues of the thiostrepton resistance methyltransferase
CL Myers, EG Kuiper, PC Grant, J Hernandez, GL Conn, JF Honek
FEBS letters 589 (21), 3263-3270, 2015
32015
Penicillin-binding protein inhibitors
CJ Burns, D Daigle, GH Chu, J Hamrick, SA Boyd, AL Zulli, SM Condon, ...
US Patent App. 18/563,292, 2024
2024
Cefepime-Taniborbactam and Ceftibuten-Ledaborbactam Maintain Activity Against KPC Variants that Lead to Ceftazidime-Avibactam Resistance
CL Myers, A Stevenson, B Miller, DM Daigle, T Uehara, DC Pevear
bioRxiv, 2024.10. 11.617870, 2024
2024
Penicillin-binding protein inhibitors
CJ Burns, D Daigle, GH Chu, J Hamrick, SA Boyd, AL Zulli, SM Condon, ...
US Patent App. 17/779,804, 2023
2023
Combination compositions comprising a beta-lactamase inhibitor and uses thereof
CJ Burns, D Daigle, J Hamrick, DC Pevear, REL TROUT, L Xerri, ...
US Patent App. 17/296,371, 2022
2022
Compositions mixtes comprenant un inhibiteur de bêta-lactamase et leurs utilisations
CJ Burns, SM Condon, D Daigle, A Drager, J Hamrick, T Henkel, ...
2021
Composições de combinação que compreendem um inibidor de beta-lactamase e usos das mesmas
CJ Burns, A Drager, L Rosen, D DAIGLE, J HAMRICK, DC Pevear, ...
2021
Combination compositions comprising a beta-lactamase inhibitor and uses thereof
CJ Burns, D Daigle, J HAMRICK, DC Pevear, REL TROUT, L XERRI, ...
2020
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