Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data NT Gupta, JA Vander Heiden, M Uduman, D Gadala-Maria, G Yaari, ... Bioinformatics 31 (20), 3356-3358, 2015 | 717 | 2015 |
B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes JNH Stern, G Yaari, JA Vander Heiden, G Church, WF Donahue, ... Science translational medicine 6 (248), 248ra107-248ra107, 2014 | 471 | 2014 |
pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires JA Vander Heiden, G Yaari, M Uduman, JNH Stern, KC O’connor, ... Bioinformatics 30 (13), 1930-1932, 2014 | 453 | 2014 |
Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data G Yaari, JA Vander Heiden, M Uduman, D Gadala-Maria, N Gupta, ... Frontiers in immunology 4, 358, 2013 | 245 | 2013 |
Salmonella infection drives promiscuous B cell activation followed by extrafollicular affinity maturation R Di Niro, SJ Lee, JA Vander Heiden, RA Elsner, N Trivedi, JM Bannock, ... Immunity 43 (1), 120-131, 2015 | 221 | 2015 |
High-resolution antibody dynamics of vaccine-induced immune responses U Laserson, F Vigneault, D Gadala-Maria, G Yaari, M Uduman, ... Proceedings of the National Academy of Sciences 111 (13), 4928-4933, 2014 | 204 | 2014 |
Interleukin-10 from CD4+ follicular regulatory T cells promotes the germinal center response BJ Laidlaw, Y Lu, RA Amezquita, JS Weinstein, JA Vander Heiden, ... Science immunology 2 (16), eaan4767, 2017 | 180 | 2017 |
In vivo partial reprogramming alters age-associated molecular changes during physiological aging in mice KC Browder, P Reddy, M Yamamoto, A Haghani, IG Guillen, S Sahu, ... Nature Aging 2 (3), 243-253, 2022 | 139 | 2022 |
Shared genetic basis for migraine and ischemic stroke: a genome-wide analysis of common variants R Malik, T Freilinger, BS Winsvold, V Anttila, J Vander Heiden, M Traylor, ... Neurology 84 (21), 2132-2145, 2015 | 136 | 2015 |
Individual heritable differences result in unique cell lymphocyte receptor repertoires of naïve and antigen-experienced cells F Rubelt, CR Bolen, HM McGuire, JAV Heiden, D Gadala-Maria, M Levin, ... Nature communications 7 (1), 1-12, 2016 | 121 | 2016 |
Dysregulation of B cell repertoire formation in myasthenia gravis patients revealed through deep sequencing JA Vander Heiden, P Stathopoulos, JQ Zhou, L Chen, TJ Gilbert, ... The Journal of Immunology 198 (4), 1460-1473, 2017 | 117 | 2017 |
Reproducibility and reuse of adaptive immune receptor repertoire data F Breden, ET Luning Prak, B Peters, F Rubelt, CA Schramm, CE Busse, ... Frontiers in immunology 8, 1418, 2017 | 99 | 2017 |
A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment A Balestrini, V Joseph, M Dourado, RM Reese, SD Shields, L Rougé, ... Journal of Experimental Medicine 218 (4), 2021 | 92 | 2021 |
Repertoire-wide phylogenetic models of B cell molecular evolution reveal evolutionary signatures of aging and vaccination KB Hoehn, JA Vander Heiden, JQ Zhou, G Lunter, OG Pybus, ... Proceedings of the National Academy of Sciences 116 (45), 22664-22672, 2019 | 88 | 2019 |
Early B cell tolerance defects in neuromyelitis optica favour anti-AQP4 autoantibody production E Cotzomi, P Stathopoulos, CS Lee, AM Ritchie, JN Soltys, FR Delmotte, ... Brain 142 (6), 1598-1615, 2019 | 87 | 2019 |
Genetic analysis for a shared biological basis between migraine and coronary artery disease BS Winsvold, CP Nelson, R Malik, P Gormley, V Anttila, J Vander Heiden, ... Neurology: Genetics 1 (1), e10, 2015 | 82 | 2015 |
AIRR community standardized representations for annotated immune repertoires JA Vander Heiden, S Marquez, N Marthandan, SAC Bukhari, CE Busse, ... Frontiers in immunology 9, 2206, 2018 | 79 | 2018 |
Osteopontin links myeloid activation and disease progression in systemic sclerosis X Gao, G Jia, A Guttman, DJ DePianto, KB Morshead, KH Sun, ... Cell Reports Medicine 1 (8), 2020 | 74 | 2020 |
A model of somatic hypermutation targeting in mice based on high-throughput Ig sequencing data A Cui, R Di Niro, JA Vander Heiden, AW Briggs, K Adams, T Gilbert, ... The Journal of Immunology 197 (9), 3566-3574, 2016 | 74 | 2016 |
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis T Sun, Z Huang, WC Liang, J Yin, WY Lin, J Wu, JM Vernes, J Lutman, ... Science translational medicine 13 (605), eabe0407, 2021 | 73 | 2021 |