Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature PG Arnison, MJ Bibb, G Bierbaum, AA Bowers, TS Bugni, G Bulaj, ... Natural product reports 30 (1), 108-160, 2013 | 2011 | 2013 |
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature PG Arnison, MJ Bibb, G Bierbaum, AA Bowers, TS Bugni, G Bulaj, ... Natural product reports 30 (1), 108-160, 2013 | 2011 | 2013 |
Total synthesis and biological mode of action of largazole: a potent class I histone deacetylase inhibitor A Bowers, N West, J Taunton, SL Schreiber, JE Bradner, RM Williams Journal of the American Chemical Society 130 (33), 11219-11222, 2008 | 216 | 2008 |
Electrochemical generation of glycosyl triflate pools T Nokami, A Shibuya, H Tsuyama, S Suga, AA Bowers, D Crich, ... Journal of the American Chemical Society 129 (35), 10922-10928, 2007 | 149 | 2007 |
Structural insights into thioether bond formation in the biosynthesis of sactipeptides TL Grove, PM Himes, S Hwang, H Yumerefendi, JB Bonanno, B Kuhlman, ... Journal of the American Chemical Society 139 (34), 11734-11744, 2017 | 141 | 2017 |
On the Use of 3,5-O-Benzylidene and 3,5-O-(Di-tert-butylsilylene)-2-O-benzylarabinothiofuranosides and Their Sulfoxides as Glycosyl Donors for the Synthesis of … D Crich, CM Pedersen, AA Bowers, DJ Wink The Journal of organic chemistry 72 (5), 1553-1565, 2007 | 139 | 2007 |
Thiopeptide antibiotics stimulate biofilm formation in Bacillus subtilis R Bleich, JD Watrous, PC Dorrestein, AA Bowers, EA Shank Proceedings of the National Academy of Sciences 112 (10), 3086-3091, 2015 | 133 | 2015 |
Synthesis and histone deacetylase inhibitory activity of largazole analogs: alteration of the zinc-binding domain and macrocyclic scaffold AA Bowers, N West, TL Newkirk, AE Troutman-Youngman, SL Schreiber, ... Organic letters 11 (6), 1301-1304, 2009 | 133 | 2009 |
Chemoenzymatic synthesis of thiazolyl peptide natural products featuring an enzyme-catalyzed formal [4+ 2] cycloaddition WJ Wever, JW Bogart, JA Baccile, AN Chan, FC Schroeder, AA Bowers Journal of the American Chemical Society 137 (10), 3494-3497, 2015 | 126 | 2015 |
Synthesis and conformation− activity relationships of the peptide isosteres of FK228 and largazole AA Bowers, TJ Greshock, N West, G Estiu, SL Schreiber, O Wiest, ... Journal of the American Chemical Society 131 (8), 2900-2905, 2009 | 125 | 2009 |
Manipulation of thiocillin variants by prepeptide gene replacement: structure, conformation, and activity of heterocycle substitution mutants AA Bowers, MG Acker, A Koglin, CT Walsh Journal of the American Chemical Society 132 (21), 7519-7527, 2010 | 124 | 2010 |
Inhibition of cell differentiation in Bacillus subtilis by Pseudomonas protegens MJ Powers, E Sanabria-Valentín, AA Bowers, EA Shank Journal of bacteriology 197 (13), 2129-2138, 2015 | 111 | 2015 |
Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases L Lauinger, J Li, A Shostak, IA Cemel, N Ha, Y Zhang, PE Merkl, ... Nature chemical biology 13 (7), 709-714, 2017 | 107 | 2017 |
Dithiolopyrrolones: biosynthesis, synthesis, and activity of a unique class of disulfide-containing antibiotics B Li, WJ Wever, CT Walsh, AA Bowers Natural product reports 31 (7), 905-923, 2014 | 103 | 2014 |
Thiazolyl peptide antibiotic biosynthesis: a cascade of post-translational modifications on ribosomal nascent proteins CT Walsh, MG Acker, AA Bowers Journal of biological chemistry 285 (36), 27525-27531, 2010 | 102 | 2010 |
Visible Light Mediated Activation and O-Glycosylation of Thioglycosides WJ Wever, MA Cinelli, AA Bowers Organic letters 15 (1), 30-33, 2013 | 101 | 2013 |
Discovery, biological activity, synthesis and potential therapeutic utility of naturally occurring histone deacetylase inhibitors TL Newkirk, AA Bowers, RM Williams Natural product reports 26 (10), 1293-1320, 2009 | 91 | 2009 |
Generation of Thiocillin Variants by Prepeptide Gene Replacement and in Vivo Processing by Bacillus cereus MG Acker, AA Bowers, CT Walsh Journal of the American Chemical Society 131 (48), 17563-17565, 2009 | 88 | 2009 |
Dehydroamino acids: chemical multi-tools for late-stage diversification JW Bogart, AA Bowers Organic & biomolecular chemistry 17 (15), 3653-3669, 2019 | 86 | 2019 |
Genetic Interception and Structural Characterization of Thiopeptide Cyclization Precursors from Bacillus cereus AA Bowers, CT Walsh, MG Acker Journal of the American Chemical Society 132 (35), 12182-12184, 2010 | 82 | 2010 |