NF1 mutation drives neuronal activity-dependent initiation of optic glioma Y Pan, JD Hysinger, T Barron, NF Schindler, O Cobb, X Guo, B Yalçın, ... Nature 594 (7862), 277-282, 2021 | 108 | 2021 |
RNA sequencing of tumor-associated microglia reveals Ccl5 as a stromal chemokine critical for neurofibromatosis-1 glioma growth AC Solga, WW Pong, KY Kim, PJ Cimino, JA Toonen, J Walker, T Wylie, ... Neoplasia 17 (10), 776-788, 2015 | 94 | 2015 |
Akt- or MEK-mediated mTOR inhibition suppresses Nf1 optic glioma growth A Kaul, JA Toonen, PJ Cimino, SM Gianino, DH Gutmann Neuro-oncology 17 (6), 843-853, 2015 | 89 | 2015 |
NF1 germline mutation differentially dictates optic glioma formation and growth in neurofibromatosis-1 JA Toonen, C Anastasaki, LJ Smithson, SM Gianino, K Li, RA Kesterson, ... Human molecular genetics 25 (9), 1703-1713, 2016 | 77 | 2016 |
Estrogen activation of microglia underlies the sexually dimorphic differences in Nf1 optic glioma–induced retinal pathology JA Toonen, AC Solga, Y Ma, DH Gutmann Journal of Experimental Medicine 214 (1), 17-25, 2017 | 62 | 2017 |
Defining the temporal course of murine neurofibromatosis-1 optic gliomagenesis reveals a therapeutic window to attenuate retinal dysfunction JA Toonen, Y Ma, DH Gutmann Neuro-oncology 19 (6), 808-819, 2017 | 42 | 2017 |
The cell of origin dictates the temporal course of neurofibromatosis-1 (Nf1) low-grade glioma formation AC Solga, JA Toonen, Y Pan, PJ Cimino, Y Ma, GA Castillon, SM Gianino, ... Oncotarget 8 (29), 47206, 2017 | 31 | 2017 |
Waved with open eyelids 2 (woe2) is a novel spontaneous mouse mutation in the protein phosphatase 1, regulatory (inhibitor) subunit 13 like (Ppp1r13l)gene J Toonen, L Liang, DJ Sidjanin BMC genetics 13, 1-10, 2012 | 26 | 2012 |
Increased tissue stiffness in tumors from mice with neurofibromatosis-1 optic glioma C Walter, L Crawford, M Lai, JA Toonen, Y Pan, S Sakiyama-Elbert, ... Biophysical journal 112 (8), 1535-1538, 2017 | 24 | 2017 |
The impact of coexisting genetic mutations on murine optic glioma biology A Kaul, JA Toonen, SM Gianino, DH Gutmann Neuro-oncology 17 (5), 670-677, 2015 | 22 | 2015 |
ADAM17 transactivates EGFR signaling during embryonic eyelid closure EL Hassemer, B Endres, JA Toonen, A Ronchetti, R Dubielzig, ... Investigative ophthalmology & visual science 54 (1), 132-140, 2013 | 22 | 2013 |
Whole tumor RNA-sequencing and deconvolution reveal a clinically-prognostic PTEN/PI3K-regulated glioma transcriptional signature Y Pan, EC Bush, JA Toonen, Y Ma, AC Solga, PA Sims, DH Gutmann Oncotarget 8 (32), 52474, 2017 | 21 | 2017 |
A Disintegrin and metalloproteinase10 (ADAM10) regulates NOTCH signaling during early retinal development JA Toonen, A Ronchetti, DJ Sidjanin PLoS One 11 (5), e0156184, 2016 | 20 | 2016 |
Contextual signaling in cancer LJ Smithson, C Anastasaki, R Chen, JA Toonen, SB Williams, ... Seminars in cell & developmental biology 58, 118-126, 2016 | 10 | 2016 |
Whole tumor RNA-sequencing and deconvolution reveal a clinically-prognostic PTEN/PI3K-regulated glioma transcriptional signature. Oncotarget. 2017; 8: 52474–87 Y Pan, EC Bush, JA Toonen, Y Ma, AC Solga, PA Sims, DH Gutmann, ... Impact Journals, 0 | 5 | |
The role of ADAM10 in retinal development J Toonen, D Sidjanin Investigative Ophthalmology & Visual Science 54 (15), 5151-5151, 2013 | 2 | 2013 |
TAMI-69. NF1 MUTATION DRIVES NEURONAL ACTIVITY-DEPENDENT OPTIC GLIOMA INITIATION Y Pan, J Hysinger, T Barron, N Schindler, O Cobb, X Guo, B Yalçın, ... Neuro-Oncology 23 (Suppl 6), vi212, 2021 | 1 | 2021 |
LGG-01. NF1 MUTATION DRIVES NEURONAL ACTIVITY-DEPENDENT OPTIC GLIOMA INITIATION Y Pan, J Hysinger, N Schindler, O Cobb, X Guo, B Yalçın, C Anastasaki, ... Neuro-Oncology 23 (Suppl 1), i31, 2021 | | 2021 |
Abstract P1-08-01: Regulation of estrogen receptor-α by NF1 ZY Zheng, B Cakar, P Lavere, J Cao, J Yao, P Singh, JT Lei, JA Toonen, ... Cancer Research 77 (4_Supplement), P1-08-01-P1-08-01, 2017 | | 2017 |
Adisintegrin and metalloproteinase 10 (ADAM10) is a regulator of lens development DJ Sidjanin, J Toonen Investigative Ophthalmology & Visual Science 56 (7), 4007-4007, 2015 | | 2015 |