FinnGen provides genetic insights from a well-phenotyped isolated population MI Kurki, J Karjalainen, P Palta, TP Sipilä, K Kristiansson, KM Donner, ... Nature 613 (7944), 508-518, 2023 | 787 | 2023 |
Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 755 | 2021 |
Immunogenomic landscape of hematological malignancies O Dufva, P Pölönen, O Brück, MAI Keränen, J Klievink, J Mehtonen, ... Cancer Cell 38 (3), 380-399. e13, 2020 | 138 | 2020 |
Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture M Bouvy-Liivrand, A Hernández de Sande, P Pölönen, J Mehtonen, ... Nucleic acids research 45 (17), 9837-9849, 2017 | 55 | 2017 |
Transcription-coupled genetic instability marks acute lymphoblastic leukemia structural variation hotspots M Heinäniemi, T Vuorenmaa, S Teppo, MU Kaikkonen, M Bouvy-Liivrand, ... Elife 5, e13087, 2016 | 43 | 2016 |
In silico and preclinical drug screening identifies dasatinib as a targeted therapy for T-ALL S Laukkanen, T Grönroos, P Pölönen, H Kuusanmäki, J Mehtonen, ... Blood cancer journal 7 (9), e604-e604, 2017 | 32 | 2017 |
Hemap: An Interactive Online Resource for Characterizing Molecular Phenotypes across Hematologic Malignancies P Pölönen, J Mehtonen, J Lin, T Liuksiala, S Häyrynen, S Teppo, ... Cancer research 79 (10), 2466-2479, 2019 | 29 | 2019 |
Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1-positive pediatric leukemia identifies drug-targetable … J Mehtonen, S Teppo, M Lahnalampi, A Kokko, R Kaukonen, L Oksa, ... Genome Medicine 12 (1), 2020 | 25 | 2020 |
Semisupervised generative autoencoder for single-cell data TN Trong, J Mehtonen, G González, R Kramer, V Hautamäki, ... Journal of Computational Biology 27 (8), 1190-1203, 2020 | 20* | 2020 |
Data-driven characterization of molecular phenotypes across heterogeneous sample collections J Mehtonen, P Pölönen, S Häyrynen, O Dufva, J Lin, T Liuksiala, ... Nucleic acids research 47 (13), e76-e76, 2019 | 20 | 2019 |
IGF2BP3 Associates with Proliferative Phenotype and Prognostic Features in B-Cell Acute Lymphoblastic Leukemia A Mäkinen, A Nikkilä, T Haapaniemi, L Oksa, J Mehtonen, M Vänskä, ... Cancers 13 (7), 1505, 2021 | 13 | 2021 |
Predicting residential radon concentrations in Finland A Nikkilä, H Arvela, J Mehtonen, J Raitanen, M Heinäniemi, O Lohi, ... Scandinavian journal of work, environment & health 46 (3), 278-292, 2020 | 13 | 2020 |
Genetic predictors of lifelong medication-use patterns in cardiometabolic diseases T Kiiskinen, P Helkkula, K Krebs, J Karjalainen, E Saarentaus, N Mars, ... Nature medicine 29 (1), 209-218, 2023 | 11 | 2023 |
Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis SE Ruotsalainen, I Surakka, N Mars, J Karjalainen, M Kurki, M Kanai, ... Communications biology 5 (1), 802, 2022 | 10 | 2022 |
Germline POT1 deregulation can predispose to myeloid malignancies in childhood P Michler, A Schedel, M Witschas, UA Friedrich, R Wagener, J Mehtonen, ... International Journal of Molecular Sciences 22 (21), 11572, 2021 | 10 | 2021 |
Clinicopathological features and prognostic value of SOX11 in childhood acute lymphoblastic leukemia T Grönroos, A Mäkinen, S Laukkanen, J Mehtonen, A Nikkilä, L Oksa, ... Scientific reports 10 (1), 2043, 2020 | 8 | 2020 |
Overexpression of PTP4A3 in ETV6-RUNX1 acute lymphoblastic leukemia T Grönroos, S Teppo, J Mehtonen, S Laukkanen, T Liuksiala, M Nykter, ... Leukemia Research 54, 1-6, 2017 | 6 | 2017 |
Overlap of genetic loci for central serous chorioretinopathy with age-related macular degeneration JT Rämö, E Abner, EHC van Dijk, X Wang, J Brinks, T Nikopensius, ... JAMA ophthalmology 141 (5), 449-457, 2023 | 5 | 2023 |
Genome-Wide Association Study Identifies 4 Novel Risk Loci for Small Intestinal Neuroendocrine Tumors Including a Missense Mutation in LGR5 AK Giri, M Aavikko, L Wartiovaara, T Lemmetyinen, J Karjalainen, ... Gastroenterology 165 (4), 861-873, 2023 | 3 | 2023 |
Inflammatory and infectious upper respiratory diseases associate with 41 genomic loci and type 2 inflammation EC Saarentaus, J Karjalainen, JT Rämö, T Kiiskinen, AS Havulinna, ... Nature Communications 14 (1), 83, 2023 | 2 | 2023 |