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Kevin Tidgewell
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An opioid agonist that does not induce μ-opioid receptor—arrestin interactions or receptor internalization
CE Groer, K Tidgewell, RA Moyer, WW Harding, RB Rothman, ...
Molecular pharmacology 71 (2), 549-557, 2007
2802007
Neoclerodane diterpenes as a novel scaffold for μ opioid receptor ligands
WW Harding, K Tidgewell, N Byrd, H Cobb, CM Dersch, ER Butelman, ...
Journal of medicinal chemistry 48 (15), 4765-4771, 2005
1952005
2.06-The natural products chemistry of cyanobacteria
K Tidgewell, BR Clark, WH Gerwick
Comprehensive Natural Products; Liu, H.-W., Mander, L., Eds, 2010
152*2010
Evolved diversification of a modular natural product pathway: apratoxins F and G, two cytotoxic cyclic depsipeptides from a Palmyra collection of Lyngbya bouillonii
K Tidgewell, N Engene, T Byrum, J Media, T Doi, FA Valeriote, ...
ChemBioChem 11 (10), 1458-1466, 2010
131*2010
Dragonamide E, a Modified Linear Lipopeptide from Lyngbya majuscula with Antileishmanial Activity
MJ Balunas, RG Linington, K Tidgewell, AM Fenner, LD Ureña, GD Togna, ...
Journal of natural products 73 (1), 60-66, 2010
1252010
Pharmacokinetics of the plant‐derived κ‐opioid hallucinogen salvinorin A in nonhuman primates
MD Schmidt, MS Schmidt, ER Butelman, WW Harding, K Tidgewell, ...
Synapse 58 (3), 208-210, 2005
1122005
k Opioids as potential treatments for stimulant dependence
TE Prisinzano, K Tidgewell, WW Harding
The AAPS journal 7, E592-E599, 2005
972005
Salvinicins A and B, New Neoclerodane Diterpenes from Salvia divinorum
WW Harding, K Tidgewell, M Schmidt, K Shah, CM Dersch, J Snyder, ...
Organic letters 7 (14), 3017-3020, 2005
872005
Determination of Salvinorin A in body fluids by high performance liquid chromatography–atmospheric pressure chemical ionization
MS Schmidt, TE Prisinzano, K Tidgewell, W Harding, ER Butelman, ...
Journal of Chromatography B 818 (2), 221-225, 2005
862005
Synthesis and determination of the absolute configuration of the enantiomers of modafinil
T Prisinzano, J Podobinski, K Tidgewell, M Luo, D Swenson
Tetrahedron: Asymmetry 15 (6), 1053-1058, 2004
862004
Herkinorin analogues with differential β-arrestin-2 interactions
K Tidgewell, CE Groer, WW Harding, A Lozama, M Schmidt, A Marquam, ...
Journal of medicinal chemistry 51 (8), 2421-2431, 2008
812008
Salvinorin A: allosteric interactions at the μ-opioid receptor
RB Rothman, DL Murphy, H Xu, JA Godin, CM Dersch, JS Partilla, ...
Journal of Pharmacology and Experimental Therapeutics 320 (2), 801-810, 2007
812007
A facile method for the preparation of deuterium labeled salvinorin A: synthesis of [2, 2, 2-2H3]-salvinorin A
K Tidgewell, WW Harding, M Schmidt, KG Holden, DJ Murry, ...
Bioorganic & Medicinal Chemistry Letters 14 (20), 5099-5102, 2004
802004
Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum:  Semisynthesis of Salvinicins A and B and Other Chemical Transformations of Salvinorin A
WW Harding, M Schmidt, K Tidgewell, P Kannan, KG Holden, B Gilmour, ...
Journal of natural products 69 (1), 107-112, 2006
782006
Coibacins A–D, antileishmanial marine cyanobacterial polyketides with intriguing biosynthetic origins
MJ Balunas, MF Grosso, FA Villa, N Engene, KL McPhail, K Tidgewell, ...
Organic letters 14 (15), 3878-3881, 2012
732012
Synthesis of salvinorin A analogues as opioid receptor probes
K Tidgewell, WW Harding, A Lozama, H Cobb, K Shah, P Kannan, ...
Journal of natural products 69 (6), 914-918, 2006
702006
Synthetic studies of neoclerodane diterpenes from Salvia divinorum: selective modification of the furan ring
WW Harding, M Schmidt, K Tidgewell, P Kannan, KG Holden, CM Dersch, ...
Bioorganic & Medicinal Chemistry Letters 16 (12), 3170-3174, 2006
672006
A comparison of noninternalizing (herkinorin) and internalizing (DAMGO) μ‐opioid agonists on cellular markers related to opioid tolerance and dependence
H Xu, JS Partilla, X Wang, JM Rutherford, K Tidgewell, TE Prisinzano, ...
Synapse 61 (3), 166-175, 2007
652007
Antinociceptive effects of herkinorin, a MOP receptor agonist derived from salvinorin A in the formalin test in rats: new concepts in mu opioid receptor pharmacology: from a …
K Lamb, K Tidgewell, DS Simpson, LM Bohn, TE Prisinzano
Drug and alcohol dependence 121 (3), 181-188, 2012
642012
Effects of salvinorin A, a κ-opioid hallucinogen, on a neuroendocrine biomarker assay in nonhuman primates with high κ-receptor homology to humans
ER Butelman, M Mandau, K Tidgewell, TE Prisinzano, V Yuferov, ...
Journal of Pharmacology and Experimental Therapeutics 320 (1), 300-306, 2007
642007
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