An opioid agonist that does not induce μ-opioid receptor—arrestin interactions or receptor internalization CE Groer, K Tidgewell, RA Moyer, WW Harding, RB Rothman, ... Molecular pharmacology 71 (2), 549-557, 2007 | 280 | 2007 |
Neoclerodane diterpenes as a novel scaffold for μ opioid receptor ligands WW Harding, K Tidgewell, N Byrd, H Cobb, CM Dersch, ER Butelman, ... Journal of medicinal chemistry 48 (15), 4765-4771, 2005 | 195 | 2005 |
2.06-The natural products chemistry of cyanobacteria K Tidgewell, BR Clark, WH Gerwick Comprehensive Natural Products; Liu, H.-W., Mander, L., Eds, 2010 | 152* | 2010 |
Evolved diversification of a modular natural product pathway: apratoxins F and G, two cytotoxic cyclic depsipeptides from a Palmyra collection of Lyngbya bouillonii K Tidgewell, N Engene, T Byrum, J Media, T Doi, FA Valeriote, ... ChemBioChem 11 (10), 1458-1466, 2010 | 131* | 2010 |
Dragonamide E, a Modified Linear Lipopeptide from Lyngbya majuscula with Antileishmanial Activity MJ Balunas, RG Linington, K Tidgewell, AM Fenner, LD Ureña, GD Togna, ... Journal of natural products 73 (1), 60-66, 2010 | 125 | 2010 |
Pharmacokinetics of the plant‐derived κ‐opioid hallucinogen salvinorin A in nonhuman primates MD Schmidt, MS Schmidt, ER Butelman, WW Harding, K Tidgewell, ... Synapse 58 (3), 208-210, 2005 | 112 | 2005 |
k Opioids as potential treatments for stimulant dependence TE Prisinzano, K Tidgewell, WW Harding The AAPS journal 7, E592-E599, 2005 | 97 | 2005 |
Salvinicins A and B, New Neoclerodane Diterpenes from Salvia divinorum WW Harding, K Tidgewell, M Schmidt, K Shah, CM Dersch, J Snyder, ... Organic letters 7 (14), 3017-3020, 2005 | 87 | 2005 |
Determination of Salvinorin A in body fluids by high performance liquid chromatography–atmospheric pressure chemical ionization MS Schmidt, TE Prisinzano, K Tidgewell, W Harding, ER Butelman, ... Journal of Chromatography B 818 (2), 221-225, 2005 | 86 | 2005 |
Synthesis and determination of the absolute configuration of the enantiomers of modafinil T Prisinzano, J Podobinski, K Tidgewell, M Luo, D Swenson Tetrahedron: Asymmetry 15 (6), 1053-1058, 2004 | 86 | 2004 |
Herkinorin analogues with differential β-arrestin-2 interactions K Tidgewell, CE Groer, WW Harding, A Lozama, M Schmidt, A Marquam, ... Journal of medicinal chemistry 51 (8), 2421-2431, 2008 | 81 | 2008 |
Salvinorin A: allosteric interactions at the μ-opioid receptor RB Rothman, DL Murphy, H Xu, JA Godin, CM Dersch, JS Partilla, ... Journal of Pharmacology and Experimental Therapeutics 320 (2), 801-810, 2007 | 81 | 2007 |
A facile method for the preparation of deuterium labeled salvinorin A: synthesis of [2, 2, 2-2H3]-salvinorin A K Tidgewell, WW Harding, M Schmidt, KG Holden, DJ Murry, ... Bioorganic & Medicinal Chemistry Letters 14 (20), 5099-5102, 2004 | 80 | 2004 |
Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Semisynthesis of Salvinicins A and B and Other Chemical Transformations of Salvinorin A WW Harding, M Schmidt, K Tidgewell, P Kannan, KG Holden, B Gilmour, ... Journal of natural products 69 (1), 107-112, 2006 | 78 | 2006 |
Coibacins A–D, antileishmanial marine cyanobacterial polyketides with intriguing biosynthetic origins MJ Balunas, MF Grosso, FA Villa, N Engene, KL McPhail, K Tidgewell, ... Organic letters 14 (15), 3878-3881, 2012 | 73 | 2012 |
Synthesis of salvinorin A analogues as opioid receptor probes K Tidgewell, WW Harding, A Lozama, H Cobb, K Shah, P Kannan, ... Journal of natural products 69 (6), 914-918, 2006 | 70 | 2006 |
Synthetic studies of neoclerodane diterpenes from Salvia divinorum: selective modification of the furan ring WW Harding, M Schmidt, K Tidgewell, P Kannan, KG Holden, CM Dersch, ... Bioorganic & Medicinal Chemistry Letters 16 (12), 3170-3174, 2006 | 67 | 2006 |
A comparison of noninternalizing (herkinorin) and internalizing (DAMGO) μ‐opioid agonists on cellular markers related to opioid tolerance and dependence H Xu, JS Partilla, X Wang, JM Rutherford, K Tidgewell, TE Prisinzano, ... Synapse 61 (3), 166-175, 2007 | 65 | 2007 |
Antinociceptive effects of herkinorin, a MOP receptor agonist derived from salvinorin A in the formalin test in rats: new concepts in mu opioid receptor pharmacology: from a … K Lamb, K Tidgewell, DS Simpson, LM Bohn, TE Prisinzano Drug and alcohol dependence 121 (3), 181-188, 2012 | 64 | 2012 |
Effects of salvinorin A, a κ-opioid hallucinogen, on a neuroendocrine biomarker assay in nonhuman primates with high κ-receptor homology to humans ER Butelman, M Mandau, K Tidgewell, TE Prisinzano, V Yuferov, ... Journal of Pharmacology and Experimental Therapeutics 320 (1), 300-306, 2007 | 64 | 2007 |