Activation of concurrent apoptosis and necroptosis by SMAC mimetics for the treatment of refractory and relapsed ALL S McComb, J Aguadé-Gorgorió, L Harder, B Marovca, G Cario, C Eckert, ... Science translational medicine 8 (339), 339ra70-339ra70, 2016 | 108 | 2016 |
Mapping human haematopoietic stem cells from haemogenic endothelium to birth V Calvanese, S Capellera-Garcia, F Ma, I Fares, S Liebscher, ES Ng, ... Nature 604 (7906), 534-540, 2022 | 107 | 2022 |
Complementary activities of DOT1L and Menin inhibitors in MLL-rearranged leukemia. RT C. Dafflon, V. J. Craig, H. Méreau, J. Gräsel, B. S. Engstler, G. Hoffman ... Leukemia, 2016 | 96* | 2016 |
TNFR2 is required for RIP1-dependent cell death in human leukemia J Aguadé-Gorgorió, S McComb, C Eckert, A Guinot, B Marovca, ... Blood advances 4 (19), 4823-4833, 2020 | 11 | 2020 |
Repurposing anthelmintic agents to eradicate resistant leukemia C Mezzatesta, L Abduli, A Guinot, C Eckert, D Schewe, M Zaliova, L Vinti, ... Blood Cancer Journal 10 (6), 72, 2020 | 6 | 2020 |
Efficient generation of multi-gene knockout cell lines and patient-derived xenografts using multi-colored lenti-CRISPR-Cas9 L Behrmann, S McComb, J Aguadé-Gorgorió, Y Huang, M Hermann, ... Bio-protocol 7 (7), e2222-e2222, 2017 | 4 | 2017 |
Activation of necroptosis to overcome drug resistance in leukemia. J Aguadé-Gorgorió, BC Bornhauser Receptors and Clinical Investigation, 2016 | 1 | 2016 |
MYCT1 Controls Environmental Sensing to Maintain Self-Renewal in Human Hematopoietic Stem Cells J Aguade-Gorgorio, Y Jami-alahmadi, V Calvanese, M Kardouh, I Fares, ... Blood 142, 4042, 2023 | | 2023 |
3016–MYCT1 CONTROLS HUMAN HEMATOPOIETIC STEM CELL FUNCTION BY MODERATING ENDOCYTOSIS AND ENVIRONMENTAL SENSING J Aguadé-Gorgorió, Y Jami-Alahmadi, M Kardouh, I Fares, V Calvanese, ... Experimental Hematology 124, S58, 2023 | | 2023 |
S248: THE ENDOSOMAL ADAPTOR PROTEIN MYCT1 CONTROLS ENVIRONMENTAL SENSING IN HUMAN HSCS J Aguade-Gorgorio, Y Jami-alahmadi, M Kardouh, I Fares, V Calvanese, ... HemaSphere 6, 149-150, 2022 | | 2022 |
2001–THE ENDOSOMAL ADAPTOR PROTEIN MYCT1 CONTROLS ENVIRONMENTAL SENSING IN HUMAN HEMATOPOIETIC STEM CELLS J Aguade-Gorgorio, Y Jami-Alahmadi, M Kardouh, I Fares, VI Calvanese, ... Experimental Hematology 111, S32, 2022 | | 2022 |
THE ENDOSOMAL ADAPTOR PROTEIN MYCT1 CONTROLS HUMAN HEMATOPOIETIC STEM CELL FUNCTION J Aguade-Gorgorio, M Kardouh, Y Jami-alahmadi, I Fares, V Calvanese, ... EXPERIMENTAL HEMATOLOGY 100, S32-S32, 2021 | | 2021 |
2009–THE ENDOSOMAL ADAPTOR PROTEIN MYCT1 CONTROLS HUMAN HEMATOPOIETIC STEM CELL FUNCTION J Aguade-Gorgorio, M Kardouh, Y Jami-alahmadi, I Fares, V Calvanese, ... Experimental Hematology 100, S31-S32, 2021 | | 2021 |
PS1224 DOWNREGULATION OF ENDOTHELIAL GENE MYCT1 IN HUMAN HSCS DURING EX VIVO CULTURE COMPROMISES THEIR FUNCTION J Aguadé-Gorgorió, V Calvanese, F Lay, M Magnusson, H Mikkola HemaSphere 3 (S1), 558-559, 2019 | | 2019 |
Die another way: necroptosis as alternative route to cell death J Aguadé-Gorgorió, S McComb, MP Dobay, C Mezzatesta, G Cario, ... Klinische Pädiatrie 229 (03), A34, 2017 | | 2017 |
Exploiting alternative cell death mechanisms to overcome drug resistance in leukemia J Aguadé-Gorgorió University of Zurich, 2017 | | 2017 |
In vivo CRISPR reveals dual activation of apoptosis and necroptosis as means to eradicate drug resistant leukemia J Aguadé-Gorgorió, S McComb, G Cario, M Stanulla, C Eckert, ... Cancer Research 76 (14_Supplement), 3548-3548, 2016 | | 2016 |
Activation of Simultaneous Apoptosis and Necroptosis to Eradicate Drug Resistant Leukemia S McComb, J Aguadé-Gorgorió, B Marovca, L Harder, G Cario, C Eckert, ... Blood, The Journal of the American Society of Hematology 126 (23), 1283-1283, 2015 | | 2015 |