Growth factors, matrices, and forces combine and control stem cells DE Discher, DJ Mooney, PW Zandstra Science 324 (5935), 1673-1677, 2009 | 3128 | 2009 |
A 17-gene stemness score for rapid determination of risk in acute leukaemia SWK Ng, A Mitchell, JA Kennedy, WC Chen, J McLeod, N Ibrahimova, ... Nature 540 (7633), 433-437, 2016 | 829 | 2016 |
TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal X Varelas, R Sakuma, P Samavarchi-Tehrani, R Peerani, BM Rao, ... Nature cell biology 10 (7), 837-848, 2008 | 787 | 2008 |
Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal I Fares, J Chagraoui, Y Gareau, S Gingras, R Ruel, N Mayotte, E Csaszar, ... Science 345 (6203), 1509-1512, 2014 | 652 | 2014 |
Control of human embryonic stem cell colony and aggregate size heterogeneity influences differentiation trajectories CL Bauwens, R Peerani, S Niebruegge, KA Woodhouse, E Kumacheva, ... Stem cells 26 (9), 2300-2310, 2008 | 563 | 2008 |
Reproducible, ultra high-throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates MD Ungrin, C Joshi, A Nica, C Bauwens, PW Zandstra PloS one 3 (2), e1565, 2008 | 523 | 2008 |
A microfabricated platform to measure and manipulate the mechanics of engineered cardiac microtissues T Boudou, WR Legant, A Mu, MA Borochin, N Thavandiran, M Radisic, ... Tissue Engineering Part A 18 (9-10), 910-919, 2012 | 502 | 2012 |
Efficiency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems SM Dang, M Kyba, R Perlingeiro, GQ Daley, PW Zandstra Biotechnology and bioengineering 78 (4), 442-453, 2002 | 483 | 2002 |
Niche‐mediated control of human embryonic stem cell self‐renewal and differentiation R Peerani, BM Rao, C Bauwens, T Yin, GA Wood, A Nagy, E Kumacheva, ... The EMBO journal 26 (22), 4744-4755, 2007 | 464 | 2007 |
An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming M Gabut, P Samavarchi-Tehrani, X Wang, V Slobodeniuc, D O'Hanlon, ... Cell 147 (1), 132-146, 2011 | 442 | 2011 |
Controlled, scalable embryonic stem cell differentiation culture SM Dang, S Gerecht‐Nir, J Chen, J Itskovitz‐Eldor, PW Zandstra Stem cells 22 (3), 275-282, 2004 | 440 | 2004 |
A mass spectrometric-derived cell surface protein atlas D Bausch-Fluck, A Hofmann, T Bock, AP Frei, F Cerciello, A Jacobs, ... PloS one 10 (4), e0121314, 2015 | 438 | 2015 |
Differential cytokine effects on primitive (CD34+ CD38-) human hematopoietic cells: novel responses to Flt3-ligand and thrombopoietin. AL Petzer, PW Zandstra, JM Piret, CJ Eaves The Journal of experimental medicine 183 (6), 2551-2558, 1996 | 433 | 1996 |
Cytokine manipulation of primitive human hematopoietic cell self-renewal PW Zandstra, E Conneally, AL Petzer, JM Piret, CJ Eaves Proceedings of the National Academy of Sciences 94 (9), 4698-4703, 1997 | 378 | 1997 |
The systematic production of cells for cell therapies DC Kirouac, PW Zandstra Cell stem cell 3 (4), 369-381, 2008 | 360 | 2008 |
Scalable production of embryonic stem cell-derived cardiomyocytes PW Zandstra, C Bauwens, T Yin, Q Liu, H Schiller, R Zweigerdt, ... Tissue engineering 9 (4), 767-778, 2003 | 352 | 2003 |
Shear‐controlled single‐step mouse embryonic stem cell expansion and embryoid body–based differentiation EYL Fok, PW Zandstra Stem Cells 23 (9), 1333-1342, 2005 | 323 | 2005 |
Design and formulation of functional pluripotent stem cell-derived cardiac microtissues N Thavandiran, N Dubois, A Mikryukov, S Massé, B Beca, CA Simmons, ... Proceedings of the National Academy of Sciences 110 (49), E4698-E4707, 2013 | 320 | 2013 |
A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies C Bahr, L Von Paleske, VV Uslu, S Remeseiro, N Takayama, SW Ng, ... Nature 553 (7689), 515-520, 2018 | 311 | 2018 |
Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling E Csaszar, DC Kirouac, M Yu, WJ Wang, W Qiao, MP Cooke, AE Boitano, ... Cell stem cell 10 (2), 218-229, 2012 | 305 | 2012 |