Phosphoenolpyruvate is a metabolic checkpoint of anti-tumor T cell responses PC Ho, JD Bihuniak, AN Macintyre, M Staron, X Liu, R Amezquita, ... Cell 162 (6), 1217-1228, 2015 | 1306 | 2015 |
Orchestrating single-cell analysis with Bioconductor RA Amezquita, ATL Lun, E Becht, VJ Carey, LN Carpp, L Geistlinger, ... Nature methods 17 (2), 137-145, 2020 | 701 | 2020 |
IL-7-induced glycerol transport and TAG synthesis promotes memory CD8+ T cell longevity G Cui, MM Staron, SM Gray, PC Ho, RA Amezquita, J Wu, SM Kaech Cell 161 (4), 750-761, 2015 | 350 | 2015 |
The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection CX Dominguez, RA Amezquita, T Guan, HD Marshall, NS Joshi, ... Journal of Experimental Medicine 212 (12), 2041-2056, 2015 | 263 | 2015 |
Polycomb repressive complex 2-mediated chromatin repression guides effector CD8+ T cell terminal differentiation and loss of multipotency SM Gray, RA Amezquita, T Guan, SH Kleinstein, SM Kaech Immunity 46 (4), 596-608, 2017 | 235 | 2017 |
Immunogenic chemotherapy enhances recruitment of CAR-T cells to lung tumors and improves antitumor efficacy when combined with checkpoint blockade S Srivastava, SN Furlan, CA Jaeger-Ruckstuhl, M Sarvothama, C Berger, ... Cancer cell 39 (2), 193-208. e10, 2021 | 230 | 2021 |
Production of IL-10 by CD4+ regulatory T cells during the resolution of infection promotes the maturation of memory CD8+ T cells BJ Laidlaw, W Cui, RA Amezquita, SM Gray, T Guan, Y Lu, Y Kobayashi, ... Nature immunology 16 (8), 871-879, 2015 | 213 | 2015 |
Interleukin-10 from CD4+ follicular regulatory T cells promotes the germinal center response BJ Laidlaw, Y Lu, RA Amezquita, JS Weinstein, JA Vander Heiden, ... Science immunology 2 (16), eaan4767, 2017 | 178 | 2017 |
Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity CJ Perry, AR Muņoz-Rojas, KM Meeth, LN Kellman, RA Amezquita, ... Journal of Experimental Medicine 215 (3), 877-893, 2018 | 148 | 2018 |
ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8+ T cell fates T Guan, CX Dominguez, RA Amezquita, BJ Laidlaw, J Cheng, ... Journal of Experimental Medicine 215 (4), 1153-1168, 2018 | 131 | 2018 |
IL-17 promotes neutrophil-mediated immunity by activating microvascular pericytes and not endothelium R Liu, HM Lauridsen, RA Amezquita, RW Pierce, D Jane-Wit, C Fang, ... The Journal of Immunology 197 (6), 2400-2408, 2016 | 123 | 2016 |
Autoreactive T cells from patients with myasthenia gravis are characterized by elevated IL-17, IFN-γ, and GM-CSF and diminished IL-10 production Y Cao, RA Amezquita, SH Kleinstein, P Stathopoulos, RJ Nowak, ... The Journal of Immunology 196 (5), 2075-2084, 2016 | 89 | 2016 |
The chronicles of T-cell exhaustion RA Amezquita, SM Kaech Nature 543 (7644), 190-191, 2017 | 39 | 2017 |
NK cell responses redefine immunological memory NM Adams, TE O’Sullivan, CD Geary, JM Karo, RA Amezquita, NS Joshi, ... The Journal of Immunology 197 (8), 2963-2970, 2016 | 35 | 2016 |
Defining cellular population dynamics at single-cell resolution during prostate cancer progression AA Germanos, S Arora, Y Zheng, ET Goddard, IM Coleman, AT Ku, ... Elife 11, e79076, 2022 | 14 | 2022 |
Transcriptional and functional analyses of neoantigen-specific CD4 T cells during a profound response to anti-PD-L1 in metastatic Merkel cell carcinoma C Church, T Pulliam, N Longino, SY Park, KS Smythe, V Makarov, N Riaz, ... Journal for immunotherapy of cancer 10 (9), 2022 | 12 | 2022 |
Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations HN Thirimanne, F Wu, DH Janssens, J Swanger, A Diab, HM Feldman, ... Elife 11, e74338, 2022 | 9 | 2022 |
Publisher Correction: Orchestrating single-cell analysis with Bioconductor RA Amezquita, ATL Lun, E Becht, VJ Carey, LN Carpp, L Geistlinger, ... Nature methods 17 (2), 242, 2020 | 8 | 2020 |
LBA74 Genomic biomarkers in peripheral blood (PB) from patients (pts) enrolled in the JAVELIN Bladder 100 trial of avelumab first-line (1L) maintenance in advanced urothelial … TB Powles, S Sridhar, J Bellmunt, C Sternberg, P Grivas, E Hunter, ... Annals of Oncology 33, S1442, 2022 | 6 | 2022 |
Th2-biased transcriptional profile predicts HIV envelope-specific polyfunctional CD4+ T Cells that correlated with reduced risk of infection in RV144 trial KW Cohen, Y Tian, C Thayer, A Seese, R Amezquita, MJ McElrath, ... The Journal of Immunology 209 (3), 526-534, 2022 | 3 | 2022 |