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Ayesha Zafar
Ayesha Zafar
Verified email at aucklanduni.ac.nz
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Cited by
Year
New water-soluble copper (II) complexes with morpholine–thiosemicarbazone hybrids: Insights into the anticancer and antibacterial mode of action
K Ohui, E Afanasenko, F Bacher, RLX Ting, A Zafar, N Blanco-Cabra, ...
Journal of medicinal chemistry 62 (2), 512-530, 2018
992018
Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models
AL Zakharenko, OA Luzina, DN Sokolov, VI Kaledin, VP Nikolin, ...
European Journal of Medicinal Chemistry 161, 581-593, 2019
672019
From Catalysis to Cancer: Toward Structure–Activity Relationships for Benzimidazol-2-ylidene-Derived N-Heterocyclic-Carbene Complexes as Anticancer Agents
NYS Lam, D Truong, H Burmeister, MV Babak, HU Holtkamp, ...
Inorganic chemistry 57 (22), 14427-14434, 2018
652018
Aminoadamantanes containing monoterpene-derived fragments as potent tyrosyl-DNA phosphodiesterase 1 inhibitors
KY Ponomarev, EV Suslov, AL Zakharenko, OD Zakharova, AD Rogachev, ...
Bioorganic Chemistry 76, 392-399, 2018
412018
A Novel Class of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Contains the Octahydro-2H-chromen-4-ol Scaffold
NS Li-Zhulanov, AL Zakharenko, AA Chepanova, J Patel, A Zafar, ...
Molecules 23 (10), 2468, 2018
362018
Synthesis and evaluation of aryliden-and hetarylidenfuranone derivatives of usnic acid as highly potent Tdp1 inhibitors
O Zakharova, O Luzina, A Zakharenko, D Sokolov, A Filimonov, ...
Bioorganic & Medicinal Chemistry 26 (15), 4470-4480, 2018
362018
Structural modifications of the antiinflammatory oxicam scaffold and preparation of anticancer organometallic compounds
A Ashraf, F Aman, S Movassaghi, A Zafar, M Kubanik, WA Siddiqui, ...
Organometallics 38 (2), 361-374, 2019
332019
Evaluation of comparative antioxidant potential of aqueous and organic fractions of Ipomoea carnea
S Arshad, D Shahwar, M Jahangir, SZ Siddiqui, T Shahzadi, M Ajaib
Journal of Medicinal Plants Research 4 (18), 1883-1887, 2010
332010
A multitargeted approach: organorhodium anticancer agent based on vorinostat as a potent histone deacetylase inhibitor
M Hanif, J Arshad, JW Astin, Z Rana, A Zafar, S Movassaghi, E Leung, ...
Angewandte Chemie International Edition 59 (34), 14609-14614, 2020
302020
Hydration free energy as a molecular descriptor in drug design: a feasibility study
A Zafar, J Reynisson
Molecular Informatics 35 (5), 207-214, 2016
302016
Investigation into Improving the Aqueous Solubility of the Thieno[2,3-b]pyridine Anti-Proliferative Agents
A Zafar, LI Pilkington, NA Haverkate, M Van Rensburg, E Leung, ...
Molecules 23 (1), 145, 2018
242018
GPCR Modulation of Thieno[2,3-b]pyridine Anti-Proliferative Agents
A Zafar, S Sari, E Leung, LI Pilkington, M Van Rensburg, D Barker, ...
Molecules 22 (12), 2254, 2017
202017
Organoruthenium and Organoosmium Complexes of 2‐Pyridinecarbothioamides Functionalized with a Sulfonamide Motif: Synthesis, Cytotoxicity and Biomolecule Interactions
J Arshad, M Hanif, A Zafar, S Movassaghi, KKH Tong, J Reynisson, ...
ChemPlusChem 83 (7), 612-619, 2018
192018
Synthesis, In Vitro, and In Silico Studies of N-(Substituted-Phenyl)-3-(4-Phenyl-1-Piperazinyl)propanamides as Potent Alkaline Phosphatase Inhibitors
MA Abbasi, M Nazir, SZ Siddiqui, H Raza, A Zafar, SAA Shah, M Shahid
Russian Journal of Bioorganic Chemistry 47, 1086-1096, 2021
162021
Inhibition of the GDP-d-Mannose Dehydrogenase from Pseudomonas aeruginosa Using Targeted Sugar Nucleotide Probes
L Beswick, E Dimitriou, S Ahmadipour, A Zafar, M Rejzek, J Reynisson, ...
ACS Chemical Biology 15 (12), 3086-3092, 2020
162020
Metal-dependent cytotoxic and kinesin spindle protein inhibitory activity of Ru, Os, Rh, and Ir half-sandwich complexes of ispinesib-derived ligands
M Łomzik, M Hanif, A Budniok, A Błauż, A Makal, DM Tchoń, ...
Inorganic Chemistry 59 (20), 14879-14890, 2020
152020
Validating TDP1 as an inhibition target for the development of chemosensitizers for camptothecin-based chemotherapy drugs
E Leung, J Patel, JA Hollywood, A Zafar, P Tomek, D Barker, LI Pilkington, ...
Oncology and Therapy 9 (2), 541-556, 2021
132021
Effective inhibitors of tyrosyl-DNA phosphodiesterase 1 based on monoterpenoids as potential agents for antitumor therapy
AA Chepanova, NS Li-Zhulanov, AS Sukhikh, A Zafar, J Reynisson, ...
Russian Journal of Bioorganic Chemistry 45, 647-655, 2019
112019
F.; Gaiddon, C.; Ott, I.; Hartinger, CG From Catalysis to Cancer: Toward Structure− Activity Relationships for Benzimidazol-2-ylidene-Derived N-Heterocyclic-Carbene Complexes …
NYS Lam, D Truong, H Burmeister, MV Babak, HU Holtkamp, ...
Inorg. Chem 57, 14427-14434, 2018
112018
The cytotoxic potential of cationic triangulenes against tumour cells
E Leung, LI Pilkington, MM Naiya, D Barker, A Zafar, C Eurtivong, ...
MedChemComm 10 (11), 1881-1891, 2019
82019
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