| A unifying model for mTORC1-mediated regulation of mRNA translation CC Thoreen, L Chantranupong, HR Keys, T Wang, NS Gray, DM Sabatini Nature 485 (7396), 109-113, 2012 | 1561 | 2012 |
| Sestrin2 is a leucine sensor for the mTORC1 pathway RL Wolfson, L Chantranupong, RA Saxton, K Shen, SM Scaria, JR Cantor, ... Science 351 (6268), 43-48, 2016 | 1151 | 2016 |
| A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1 L Bar-Peled, L Chantranupong, AD Cherniack, WW Chen, KA Ottina, ... Science 340 (6136), 1100-1106, 2013 | 1150 | 2013 |
| Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1 S Wang, ZY Tsun, RL Wolfson, K Shen, GA Wyant, ME Plovanich, ... Science 347 (6218), 188-194, 2015 | 812 | 2015 |
| The CASTOR proteins are arginine sensors for the mTORC1 pathway L Chantranupong, SM Scaria, RA Saxton, MP Gygi, K Shen, GA Wyant, ... Cell 165 (1), 153-164, 2016 | 756 | 2016 |
| The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1 ZY Tsun, L Bar-Peled, L Chantranupong, R Zoncu, T Wang, C Kim, ... Molecular cell 52 (4), 495-505, 2013 | 567 | 2013 |
| The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1 L Chantranupong, RL Wolfson, JM Orozco, RA Saxton, SM Scaria, ... Cell reports 9 (1), 1-8, 2014 | 451 | 2014 |
| Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway RA Saxton, KE Knockenhauer, RL Wolfson, L Chantranupong, ME Pacold, ... Science 351 (6268), 53-58, 2016 | 448 | 2016 |
| Nutrient-sensing mechanisms across evolution L Chantranupong, RL Wolfson, DM Sabatini Cell 161 (1), 67-83, 2015 | 336 | 2015 |
| KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1 RL Wolfson, L Chantranupong, GA Wyant, X Gu, JM Orozco, K Shen, ... Nature 543 (7645), 438-442, 2017 | 294 | 2017 |
| Mechanism of arginine sensing by CASTOR1 upstream of mTORC1 RA Saxton, L Chantranupong, KE Knockenhauer, TU Schwartz, ... Nature 536 (7615), 229-233, 2016 | 293 | 2016 |
| Architecture of the human GATOR1 and GATOR1–Rag GTPases complexes K Shen, RK Huang, EJ Brignole, KJ Condon, ML Valenstein, ... Nature 556 (7699), 64-69, 2018 | 158 | 2018 |
| Replacing Mn2+ with Co2+ in Human Arginase I Enhances Cytotoxicity toward l-Arginine Auxotrophic Cancer Cell Lines EM Stone, ES Glazer, L Chantranupong, P Cherukuri, RM Breece, ... ACS chemical biology 5 (3), 333-342, 2010 | 133 | 2010 |
| The human asparaginase-like protein 1 hASRGL1 is an Ntn hydrolase with β-aspartyl peptidase activity JR Cantor, EM Stone, L Chantranupong, G Georgiou Biochemistry 48 (46), 11026-11031, 2009 | 91 | 2009 |
| SCHEMA-designed variants of human arginase I and II reveal sequence elements important to stability and catalysis PA Romero, E Stone, C Lamb, L Chantranupong, A Krause, AE Miklos, ... ACS synthetic biology 1 (6), 221-228, 2012 | 63 | 2012 |
| Abnormal striatal development underlies the early onset of behavioral deficits in Shank3B−/− mice RT Peixoto, L Chantranupong, R Hakim, J Levasseur, W Wang, ... Cell reports 29 (7), 2016-2027. e4, 2019 | 44 | 2019 |
| Structure of the nutrient-sensing hub GATOR2 ML Valenstein, KB Rogala, PV Lalgudi, EJ Brignole, X Gu, RA Saxton, ... Nature 607 (7919), 610-616, 2022 | 36 | 2022 |
| Strategies for optimizing the serum persistence of engineered human arginase I for cancer therapy E Stone, L Chantranupong, C Gonzalez, J O'Neal, M Rani, ... Journal of controlled release 158 (1), 171-179, 2012 | 36 | 2012 |
| Rapid purification and metabolomic profiling of synaptic vesicles from mammalian brain L Chantranupong, JL Saulnier, W Wang, DR Jones, ME Pacold, ... Elife 9, e59699, 2020 | 35 | 2020 |
| The amino acid transporter SLC38A9 is a key component of a lysosomal membrane complex that signals arginine sufficiency to mTORC1 S Wang, ZY Tsun, R Wolfson, K Shen, GA Wyant, ME Plovanich, ED Yuan, ... Science (New York, NY) 347 (6218), 188, 2015 | 28 | 2015 |
