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RONA R. RAMSAY
RONA R. RAMSAY
Reader in Biochemistry, University of St Andrews
Verified email at st-and.ac.uk
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A perspective on multi-target drug discovery and design for complex diseases
RR Ramsay, MR Popovic-Nikolic, K Nikolic, E Uliassi, ML Bolognesi
Clinical and translational medicine 7, 1-14, 2018
5872018
Energy-dependent uptake of N-methyl-4-phenylpyridinium, the neurotoxic metabolite of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine, by mitochondria.
RR Ramsay, TP Singer
Journal of Biological Chemistry 261 (17), 7585-7587, 1986
5091986
Molecular enzymology of carnitine transfer and transport
RR Ramsay, RD Gandour, FR van der Leij
Biochimica et Biophysica Acta (BBA)-Protein Structure and Moleculará…, 2001
4732001
Biochemical events in the development of parkinsonism induced by 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine
TP Singer, N Castagnoli Jr, RR Ramsay, AJ Trevor
Journal of neurochemistry 49 (1), 1-8, 1987
3491987
Identification of 4-substituted 1, 2, 3-triazoles as novel oxazolidinone antibacterial agents with reduced activity against monoamine oxidase A
F Reck, F Zhou, M Girardot, G Kern, CJ Eyermann, NJ Hales, RR Ramsay, ...
Journal of medicinal chemistry 48 (2), 499-506, 2005
3452005
Inhibition of monoamine oxidase A by β-carboline derivatives
H Kim, SO Sablin, RR Ramsay
Archives of biochemistry and biophysics 337 (1), 137-142, 1997
3301997
Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+
RR Ramsay, JI Salach, TP Singer
Biochemical and biophysical research communications 134 (2), 743-748, 1986
3221986
Methylene blue and serotonin toxicity: inhibition of monoamine oxidase A (MAO A) confirms a theoretical prediction
RR Ramsay, C Dunford, PK Gillman
British journal of pharmacology 152 (6), 946-951, 2007
3152007
Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic parkinsonism
RR Ramsay, JI Salach, J Dadgar, TP Singer
Biochemical and biophysical research communications 135 (1), 269-275, 1986
3141986
Mechanism of the neurotoxicity of MPTP: an update
TP Singer, RR Ramsay
FEBS letters 274 (1-2), 1-8, 1990
2681990
Interaction of 1‐Methyl‐4‐Phenylpyridinium Ion (MPP+) and Its Analogs with the Rotenone/Piericidin Binding Site of NADH Dehydrogenase
RR Ramsay, MJ Krueger, SK Youngster, MR Gluck, JE Casida, TP Singer
Journal of neurochemistry 56 (4), 1184-1190, 1991
2521991
Assessment of enzyme inhibition: a review with examples from the development of monoamine oxidase and cholinesterase inhibitory drugs
RR Ramsay, KF Tipton
Molecules 22 (7), 1192, 2017
2402017
Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP
RR Ramsay, J Dadgar, A Trevor, TP Singer
Life sciences 39 (7), 581-588, 1986
2391986
The mechanism of fatty acid uptake by heart mitochondria: an acylcarnitine-carnitine exchange
RR Ramsay, PK Tubbs
FEBS letters 54 (1), 21-25, 1975
2211975
Role of carnitine and carnitine palmitoyltransferase as integral components of the pathway for membrane phospholipid fatty acid turnover in intact human erythrocytes.
A Arduini, G Mancinelli, GL Radatti, S Dottori, F Molajoni, RR Ramsay
Journal of Biological Chemistry 267 (18), 12673-12681, 1992
1831992
Carnitine acyltransferases and their influence on CoA pools in health and disease
RR Ramsay, VA Zammit
Molecular aspects of medicine 25 (5-6), 475-493, 2004
1752004
Carnitine, mitochondrial function and therapy
VA Zammit, RR Ramsay, M Bonomini, A Arduini
Advanced drug delivery reviews 61 (14), 1353-1362, 2009
1742009
The carnitine acyltransferases and their role in modulating acyl-CoA pools
RR Ramsay, A Arduini
Archives of biochemistry and biophysics 302 (2), 307-314, 1993
1691993
Multi-target directed donepezil-like ligands for Alzheimer's disease
M Unzeta, G Esteban, I Bolea, WA Fogel, RR Ramsay, MBH Youdim, ...
Frontiers in neuroscience 10, 197722, 2016
1522016
The inhibition site of MPP+, the neurotoxic bioactivation product of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine is near the Q-binding site of NADH dehydrogenase
RR Ramsay, AT Kowal, MK Johnson, JI Salach, TP Singer
Archives of biochemistry and biophysics 259 (2), 645-649, 1987
1471987
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