BioNetGen 2.2: advances in rule-based modeling LA Harris, JS Hogg, JJ Tapia, JAP Sekar, S Gupta, I Korsunsky, A Arora, ... Bioinformatics 32 (21), 3366-3368, 2016 | 254 | 2016 |
Adaptation of human iPSC-derived cardiomyocytes to tyrosine kinase inhibitors reduces acute cardiotoxicity via metabolic reprogramming H Wang, RP Sheehan, AC Palmer, RA Everley, SA Boswell, N Ron-Harel, ... Cell systems 8 (5), 412-426. e7, 2019 | 67 | 2019 |
Cutting edge: differential regulation of PTEN by TCR, Akt, and FoxO1 controls CD4+ T cell fate decisions WF Hawse, RP Sheehan, N Miskov-Zivanov, AV Menk, LP Kane, ... The Journal of Immunology 194 (10), 4615-4619, 2015 | 58 | 2015 |
A neutrophil phenotype model for extracorporeal treatment of sepsis AD Malkin, RP Sheehan, S Mathew, WJ Federspiel, H Redl, G Clermont PLoS computational biology 11 (10), e1004314, 2015 | 12 | 2015 |
Quantitative systems pharmacology model of the amyloid pathway in Alzheimer's disease: Insights into the therapeutic mechanisms of clinical candidates V Ramakrishnan, C Friedrich, C Witt, R Sheehan, M Pryor, JK Atwal, ... CPT: Pharmacometrics & Systems Pharmacology 12 (1), 62-73, 2023 | 10 | 2023 |
Virtual patients inspired by multiomics predict the efficacy of an anti-IFNα mAb in cutaneous lupus V Hurez, G Gauderat, P Soret, R Myers, K Dasika, R Sheehan, C Friedrich, ... iScience, 2025 | | 2025 |
Drug adaptation influences cardiotoxicity caused by tyrosine kinase inhibitors in iPSC-derived human cardiomyocytes H Wang, RP Sheehan, AC Palmer, RA Everley, SA Boswell, N Ron-Harel, ... bioRxiv, 365841, 2018 | | 2018 |
Unraveling how T cell antigen receptor signaling strength determines T cell differentiation using a combined experimental and computational approach J Faeder, RP Sheehan, WF Hawse, MJ Gable, REC Lee, PA Morel The Journal of Immunology 198 (1_Supplement), 150.19-150.19, 2017 | | 2017 |
Evaluation of Galectin-9 blocking mono-clonal antibodies as novel immune-checkpoint inhibitors via the targeting of regulatory T cells in cancer PA Morel, WF Hawse, RP Sheehan, WC Boggess, JR Faeder EUROPEAN JOURNAL OF IMMUNOLOGY 46, 14-15, 2016 | | 2016 |
TCR signal strength regulates Akt substrate specificity to induce alternate Th and Treg differentiation programs PA Morel, WF Hawse, RP Sheehan, WC Boggess, JR Faeder The Journal of Immunology 196 (1_Supplement), 128.10-128.10, 2016 | | 2016 |
Closing the loop: A combined computational modeling and experimental approach provides novel insights into immune cell signaling systems and their global effects RP Sheehan Jr University of Pittsburgh, 2016 | | 2016 |
Systems biology approach to determine critical T cell receptor signaling events for the induction of regulatory T cells (LYM8P. 639) R Sheehan, W Hawse, P Morel, J Faeder The Journal of Immunology 194 (1_Supplement), 201.15-201.15, 2015 | | 2015 |
A computational model for mechanistic investigation of negative feedback in interleukin-17 receptor signaling (CCR3P. 201) R Sheehan, A Garg, S Gaffen, J Faeder The Journal of Immunology 194 (1_Supplement), 49.2-49.2, 2015 | | 2015 |
A computational model for mechanistic investigation of negative feedback in Inerleukin-17 receptor signaling (CCR6P. 274) R Sheehan, A Garg, S Gaffen, J Faeder The Journal of Immunology 192 (1_Supplement), 182.6-182.6, 2014 | | 2014 |
Neutrophil phenotype model for extracorporeal treatment of sepsis A Malkin, R Sheehan, S Mathew, H Redl, G Clermont Critical Care 18, 1-182, 2014 | | 2014 |
Computational model for mechanistic investigation of negative feedback in Interleukin-17 receptor signaling RP Sheehan, A Garg, SL Gaffen, JR Faeder CYTOKINE 63 (3), 299-299, 2013 | | 2013 |
236: Computational model for mechanistic investigation of negative feedback in Interleukin-17 receptor signaling RP Sheehan, A Garg, SL Gaffen, JR Faeder Cytokine 63 (3), 299, 2013 | | 2013 |
Heterochromatin Is Retained During Lens Fiber Cell Differentiation MK Duncan, RP Sheehan Investigative Ophthalmology & Visual Science 52 (14), 2779-2779, 2011 | | 2011 |
Heterochromatin is retained during lens fiber cell differentiation RP Sheehan, MK Duncan The FASEB Journal 25, 896.7-896.7, 2011 | | 2011 |
The Effects of Histone Modifications on Lens Cell Denucleation RP Sheehan, M Duncan The FASEB Journal 24, 460.3-460.3, 2010 | | 2010 |