Bruno Valeria
Bruno Valeria
Professore di Farmacologia, Universitā Sapienza, Roma
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Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders?
F Nicoletti, V Bruno, A Copani, G Casabona, T Knöpfel
Trends in neurosciences 19 (7), 267-271, 1996
β-amyloid monomers are neuroprotective
ML Giuffrida, F Caraci, B Pignataro, S Cataldo, P De Bona, V Bruno, ...
Journal of Neuroscience 29 (34), 10582-10587, 2009
Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs
V Bruno, G Battaglia, A Copani, M D'Onofrio, P Di Iorio, A De Blasi, ...
Journal of Cerebral Blood Flow & Metabolism 21 (9), 1013-1033, 2001
Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-β
V Bruno, G Battaglia, G Casabona, A Copani, F Caciagli, F Nicoletti
Journal of Neuroscience 18 (23), 9594-9600, 1998
Activation of cell-cycle-associated proteins in neuronal death: a mandatory or dispensable path?
A Copani, MA Sortino, F Nicoletti, V Bruno, D Ubertia, M Memo
Trends in neurosciences 24 (1), 25-31, 2001
Glia modulate the response of murine cortical neurons to excitotoxicity: glia exacerbate AMPA neurotoxicity
LL Dugan, VM Bruno, SM Amagasu, RG Giffard
Journal of Neuroscience 15 (6), 4545-4555, 1995
Activation of A1 adenosine or mGlu3 metabotropic glutamate receptors enhances the release of nerve growth factor and S‐100β protein from cultured astrocytes
R Ciccarelli, P Di Iorio, V Bruno, G Battaglia, I D'Alimonte, M D'onofrio, ...
Glia 27 (3), 275-281, 1999
(−)-PHCCC, a positive allosteric modulator of mGluR4: characterization, mechanism of action, and neuroprotection
M Maj, V Bruno, Z Dragic, R Yamamoto, G Battaglia, W Inderbitzin, ...
Neuropharmacology 45 (7), 895-906, 2003
The use of knock-out mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/neuroprotection
C Corti, G Battaglia, G Molinaro, B Riozzi, A Pittaluga, M Corsi, ...
Journal of Neuroscience 27 (31), 8297-8308, 2007
TGF‐β1 Pathway as a New Target for Neuroprotection in Alzheimer's Disease
F Caraci, G Battaglia, V Bruno, P Bosco, V Carbonaro, ML Giuffrida, ...
CNS neuroscience & therapeutics 17 (4), 237-249, 2011
Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide.
A Copani, V Bruno, G Battaglia, G Leanza, R Pellitteri, A Russo, ...
Molecular pharmacology 47 (5), 890-897, 1995
Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells
V Bruno, A Copani, T Knöpfel, R Kuhn, G Casabona, P Dell'Albani, ...
Neuropharmacology 34 (8), 1089-1098, 1995
Group-I metabotropic glutamate receptors: hypotheses to explain their dual role in neurotoxicity and neuroprotection
F Nicoletti, V Bruno, MV Catania, G Battaglia, A Copani, G Barbagallo, ...
Neuropharmacology 38 (10), 1477-1484, 1999
(R, S)-4-phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo
F Gasparini, V Bruno, G Battaglia, S Lukic, T Leonhardt, W Inderbitzin, ...
Journal of Pharmacology and Experimental Therapeutics 289 (3), 1678-1687, 1999
Activation of class II or III metabotropic glutamate receptors protects cultured cortical neurons against excitotoxic degeneration
V Bruno, G Battaglia, A Copani, RG Giffard, G Raciti, R Raffaele, ...
European Journal of Neuroscience 7 (9), 1906-1913, 1995
The neuroprotective activity of group-II metabotropic glutamate receptors requires new protein synthesis and involves a glial–neuronal signaling
V Bruno, FX Sureda, M Storto, G Casabona, A Caruso, T Knopfel, R Kuhn, ...
Journal of Neuroscience 17 (6), 1891-1897, 1997
Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is required for the development of ischemic neuronal death
I Cappuccio, A Calderone, CL Busceti, F Biagioni, F Pontarelli, V Bruno, ...
Journal of Neuroscience 25 (10), 2647-2657, 2005
Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation
F Fallarino, C Volpi, F Fazio, S Notartomaso, C Vacca, C Busceti, ...
Nature medicine 16 (8), 897-902, 2010
Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death
V Bruno, A Copani, G Battaglia, R Raffaele, H Shinozaki, F Nicoletti
European journal of pharmacology 256 (1), 109-112, 1994
Selective blockade of metabotropic glutamate receptor subtype 5 is neuroprotective
V Bruno, I Ksiazek, G Battaglia, S Lukic, T Leonhardt, D Sauer, ...
Neuropharmacology 39 (12), 2223-2230, 2000
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