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Marat Alimzhanov
Marat Alimzhanov
EMD Serono
Подтвержден адрес электронной почты в домене emdserono.com
Название
Процитировано
Процитировано
Год
Survival of resting mature B lymphocytes depends on BCR signaling via the Igα/β heterodimer
M Kraus, MB Alimzhanov, N Rajewsky, K Rajewsky
Cell 117 (6), 787-800, 2004
7262004
B cell receptor signal strength determines B cell fate
S Casola, KL Otipoby, M Alimzhanov, S Humme, N Uyttersprot, JL Kutok, ...
Nature immunology 5 (3), 317-327, 2004
6912004
The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors
M Hedvat, D Huszar, A Herrmann, JM Gozgit, A Schroeder, A Sheehy, ...
Cancer cell 16 (6), 487-497, 2009
5982009
Abnormal development of secondary lymphoid tissues in lymphotoxin β-deficient mice
MB Alimzhanov, DV Kuprash, MH Kosco-Vilbois, A Luz, RL Turetskaya, ...
Proceedings of the National Academy of Sciences 94 (17), 9302-9307, 1997
4601997
Identification and characterization of MEDI4736, an antagonistic anti–PD-L1 monoclonal antibody
R Stewart, M Morrow, SA Hammond, K Mulgrew, D Marcus, E Poon, ...
Cancer immunology research 3 (9), 1052-1062, 2015
3912015
Mature follicular dendritic cell networks depend on expression of lymphotoxin β receptor by radioresistant stromal cells and of lymphotoxin β and tumor necrosis factor by B cells
R Endres, MB Alimzhanov, T Plitz, A Fütterer, MH Kosco-Vilbois, ...
The Journal of experimental medicine 189 (1), 159-168, 1999
3761999
Targeted binding agents against B7-H1
C Queva, M Morrow, S Hammond, M Alimzhanov, J Babcook, IN Foltz, ...
US Patent 8,779,108, 2014
3122014
B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity
LI Pao, KP Lam, JM Henderson, JL Kutok, M Alimzhanov, L Nitschke, ...
Immunity 27 (1), 35-48, 2007
3102007
FDC-specific functions of p55TNFR and IKK2 in the development of FDC networks and of antibody responses
P Victoratos, J Lagnel, S Tzima, MB Alimzhanov, K Rajewsky, ...
Immunity 24 (1), 65-77, 2006
1472006
Discovery of 5-Chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine (AZD1480) as a Novel Inhibitor of the Jak …
S Ioannidis, ML Lamb, T Wang, L Almeida, MH Block, AM Davies, B Peng, ...
Journal of medicinal chemistry 54 (1), 262-276, 2011
1362011
TNF and lymphotoxin β cooperate in the maintenance of secondary lymphoid tissue microarchitecture but not in the development of lymph nodes
DV Kuprash23, MB Alimzhanov, AV Tumanov, AO Anderson, K Pfeffer, ...
The Journal of Immunology 163 (12), 6575-6580, 1999
1021999
Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching
JH Wang, FW Alt, M Gostissa, A Datta, M Murphy, MB Alimzhanov, ...
The Journal of experimental medicine 205 (13), 3079-3090, 2008
832008
Redundancy in tumor necrosis factor (TNF) and lymphotoxin (LT) signaling in vivo: mice with inactivation of the entire TNF/LT locus versus single-knockout mice
DV Kuprash, MB Alimzhanov, AV Tumanov, SI Grivennikov, AN Shakhov, ...
Molecular and cellular biology 22 (24), 8626-8634, 2002
812002
Cloning and expression analysis of the murine lymphotoxin beta gene.
DK Pokholok, IG Maroulakou, DV Kuprash, MB Alimzhanov, SV Kozlov, ...
Proceedings of the National Academy of Sciences 92 (3), 674-678, 1995
631995
Discovery of 1-Methyl-1H-imidazole Derivatives as Potent Jak2 Inhibitors
Q Su, S Ioannidis, C Chuaqui, L Almeida, M Alimzhanov, G Bebernitz, ...
Journal of medicinal chemistry 57 (1), 144-158, 2014
592014
Potent and Selective CK2 Kinase Inhibitors with Effects on Wnt Pathway Signaling in Vivo
JE Dowling, M Alimzhanov, L Bao, C Chuaqui, CR Denz, E Jenkins, ...
ACS Medicinal Chemistry Letters 7 (3), 300-305, 2016
542016
Targeted binding agents against B7-H1
C Queva, M Morrow, S Hammond, M Alimzhanov, J Babcock, IN Foltz, ...
US Patent 9,493,565, 2016
532016
Complement C 4 maintains peripheral B‐cell tolerance in a myeloid cell dependent manner
P Chatterjee, AF Agyemang, MB Alimzhanov, S Degn, SA Tsiftsoglou, ...
European journal of immunology 43 (9), 2441-2450, 2013
482013
Structure and property based design of pyrazolo [1, 5-a] pyrimidine inhibitors of CK2 kinase with activity in vivo
JE Dowling, M Alimzhanov, L Bao, MH Block, C Chuaqui, EL Cooke, ...
ACS medicinal chemistry letters 4 (8), 800-805, 2013
472013
Functional analysis of the lymphotoxin-beta promoter. Sequence requirements for PMA activation.
DV Kuprash, OA Osipovich, DK Pokholok, MB Alimzhanov, A Biragyn, ...
Journal of immunology (Baltimore, Md.: 1950) 156 (7), 2465-2472, 1996
471996
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