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Shawn French
Shawn French
Подтвержден адрес электронной почты в домене mcmaster.ca - Главная страница
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Процитировано
Процитировано
Год
A deep learning approach to antibiotic discovery
JM Stokes, K Yang, K Swanson, W Jin, A Cubillos-Ruiz, NM Donghia, ...
Cell 180 (4), 688-702. e13, 2020
20422020
CARD 2023: expanded curation, support for machine learning, and resistome prediction at the Comprehensive Antibiotic Resistance Database
BP Alcock, W Huynh, R Chalil, KW Smith, AR Raphenya, MA Wlodarski, ...
Nucleic acids research 51 (D1), D690-D699, 2023
6652023
Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance
JM Stokes, CR MacNair, B Ilyas, S French, JP Côté, C Bouwman, ...
Nature microbiology 2 (5), 1-8, 2017
3292017
Bicarbonate alters bacterial susceptibility to antibiotics by targeting the proton motive force
MA Farha, S French, J Stokes, ED Brown
ACS infectious diseases, 2018
1252018
Assembly and clustering of natural antibiotics guides target identification
CW Johnston, MA Skinnider, CA Dejong, PN Rees, GM Chen, CG Walker, ...
Nature chemical biology 12 (4), 233-239, 2016
1122016
Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase
MA Farha, TL Czarny, CL Myers, LJ Worrall, S French, DG Conrady, ...
Proceedings of the National Academy of Sciences 112 (35), 11048-11053, 2015
1122015
Cold stress makes Escherichia coli susceptible to glycopeptide antibiotics by altering outer membrane integrity
JM Stokes, S French, OG Ovchinnikova, C Bouwman, C Whitfield, ...
Cell chemical biology 23 (2), 267-277, 2016
932016
Potentiation of antibiotics against Gram-negative bacteria by polymyxin B analogue SPR741 from unique perturbation of the outer membrane
S French, M Farha, MJ Ellis, Z Sameer, JP Côté, N Cotroneo, T Lister, ...
ACS infectious diseases 6 (6), 1405-1412, 2019
902019
Elevated temperatures and carbon dioxide concentrations: effects on selected microbial activities in temperate agricultural soils
S French, D Levy-Booth, A Samarajeewa, KE Shannon, J Smith, ...
World Journal of Microbiology and Biotechnology 25, 1887-1900, 2009
842009
A robust platform for chemical genomics in bacterial systems
S French, C Mangat, A Bharat, JP Côté, H Mori, ED Brown
Molecular biology of the cell 27 (6), 1015-1025, 2016
762016
A macrophage-based screen identifies antibacterial compounds selective for intracellular Salmonella Typhimurium
MJ Ellis, CN Tsai, JW Johnson, S French, W Elhenawy, S Porwollik, ...
Nature Communications 10 (1), 197, 2019
692019
Structural and kinetic characterization of diazabicyclooctanes as dual inhibitors of both serine-β-lactamases and penicillin-binding proteins
AM King, DT King, S French, E Brouillette, A Asli, JAN Alexander, ...
ACS chemical biology 11 (4), 864-868, 2016
672016
The genome-wide interaction network of nutrient stress genes in Escherichia coli
JP Côté, S French, SS Gehrke, CR MacNair, CS Mangat, A Bharat, ...
MBio 7 (6), 10.1128/mbio. 01714-16, 2016
572016
Discovery of Novel Cell Wall-Active Compounds Using PywaC, a Sensitive Reporter of Cell Wall Stress, in the Model Gram-Positive Bacterium Bacillus subtilis
TL Czarny, AL Perri, S French, ED Brown
Antimicrobial Agents and Chemotherapy 58 (6), 3261-3269, 2014
522014
Identification of two phosphate starvation-induced wall teichoic acid hydrolases provides first insights into the degradative pathway of a key bacterial cell wall component
CL Myers, FKK Li, BM Koo, OM El-Halfawy, S French, CA Gross, ...
Journal of Biological Chemistry 291 (50), 26066-26082, 2016
452016
Chemical screen for vancomycin antagonism uncovers probes of the gram-negative outer membrane
K Klobucar, JP Côté, S French, L Borrillo, ABY Guo, MH Serrano-Wu, ...
ACS Chemical Biology 16 (5), 929-942, 2021
442021
The dynamic nature of bacterial surfaces: Implications for metal-membrane interaction
S French, D Puddephatt, M Habash, S Glasauer
Critical Reviews in Microbiology 39 (2), 196-217, 2013
442013
Genetic and chemical screening in human blood serum reveals unique antibacterial targets and compounds against Klebsiella pneumoniae
BS Weber, AM De Jong, ABY Guo, S Dharavath, S French, ...
Cell Reports 32 (3), 2020
412020
A multiplexable assay for screening antibiotic lethality against drug-tolerant bacteria
JM Stokes, A Gutierrez, AJ Lopatkin, IW Andrews, S French, I Matic, ...
Nature Methods 16 (4), 303-306, 2019
392019
Gene dispensability in Escherichia coli grown in thirty different carbon environments
M Tong, S French, SS El Zahed, WK Ong, PD Karp, ED Brown
MBio 11 (5), 10.1128/mbio. 02259-20, 2020
372020
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