Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing L Rasche, SS Chavan, OW Stephens, PH Patel, R Tytarenko, C Ashby, ... Nature communications 8 (1), 268, 2017 | 352 | 2017 |
Low expression of hexokinase-2 is associated with false-negative FDG–positron emission tomography in multiple myeloma L Rasche, E Angtuaco, JE McDonald, A Buros, C Stein, C Pawlyn, ... Blood, The Journal of the American Society of Hematology 130 (1), 30-34, 2017 | 217 | 2017 |
Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma N Weinhold, C Ashby, L Rasche, SS Chavan, C Stein, OW Stephens, ... Blood, The Journal of the American Society of Hematology 128 (13), 1735-1744, 2016 | 215 | 2016 |
MYC dysregulation in the progression of multiple myeloma K Misund, N Keane, CK Stein, YW Asmann, G Day, S Welsh, SA Van Wier, ... Leukemia 34 (1), 322-326, 2020 | 136 | 2020 |
Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control C Pawlyn, MD Bright, AF Buros, CK Stein, Z Walters, LI Aronson, ... Blood cancer journal 7 (3), e549-e549, 2017 | 113 | 2017 |
Removing batch effects from purified plasma cell gene expression microarrays with modified ComBat CK Stein, P Qu, J Epstein, A Buros, A Rosenthal, J Crowley, G Morgan, ... BMC bioinformatics 16, 1-9, 2015 | 95 | 2015 |
Bi-allelic inactivation is more prevalent at relapse in multiple myeloma, identifying RB1 as an independent prognostic marker SS Chavan, J He, R Tytarenko, S Deshpande, P Patel, M Bailey, CK Stein, ... Blood cancer journal 7 (2), e535-e535, 2017 | 71 | 2017 |
Clinical value of molecular subtyping multiple myeloma using gene expression profiling N Weinhold, CJ Heuck, A Rosenthal, S Thanendrarajan, CK Stein, ... Leukemia 30 (2), 423-430, 2016 | 70 | 2016 |
Artesunate overcomes drug resistance in multiple myeloma by inducing mitochondrial stress and non-caspase apoptosis X Papanikolaou, S Johnson, T Garg, E Tian, R Tytarenko, Q Zhang, ... Oncotarget 5 (12), 4118, 2014 | 48 | 2014 |
Tumor burden limits bispecific antibody efficacy through T-cell exhaustion averted by concurrent cytotoxic therapy EW Meermeier, SJ Welsh, ME Sharik, MT Du, VM Garbitt, DL Riggs, ... Blood cancer discovery 2 (4), 354-369, 2021 | 46 | 2021 |
Hyperhaploidy is a novel high-risk cytogenetic subgroup in multiple myeloma JR Sawyer, E Tian, JD Shaughnessy Jr, J Epstein, CM Swanson, ... Leukemia 31 (3), 637-644, 2017 | 34 | 2017 |
Dose-dense and less dose-intense total therapy 5 for gene expression profiling-defined high-risk multiple myeloma Y Jethava, A Mitchell, M Zangari, S Waheed, C Schinke, ... Blood cancer journal 6 (7), e453-e453, 2016 | 32 | 2016 |
Identification of PIKfyve kinase as a target in multiple myeloma CB De Campos, YX Zhu, N Sepetov, S Romanov, LA Bruins, CX Shi, ... Haematologica 105 (6), 1641, 2020 | 30 | 2020 |
Monosomic loss of MIR15A/MIR16-1 is a driver of multiple myeloma proliferation and disease progression M Chesi, CK Stein, VM Garbitt, ME Sharik, YW Asmann, M Bergsagel, ... Blood cancer discovery 1 (1), 68-81, 2020 | 29 | 2020 |
The varied distribution and impact of RAS codon and other key DNA alterations across the translocation cyclin D subgroups in multiple myeloma CK Stein, C Pawlyn, S Chavan, L Rasche, N Weinhold, A Corken, A Buros, ... Oncotarget 8 (17), 27854, 2017 | 29 | 2017 |
Search for rare protein altering variants influencing susceptibility to multiple myeloma M Scales, D Chubb, SE Dobbins, DC Johnson, N Li, MJ Sternberg, ... Oncotarget 8 (22), 36203, 2017 | 15 | 2017 |
The clinical impact of macrofocal disease in multiple myeloma differs between presentation and relapse L Rasche, A Buros, N Weinhold, CK Stein, JE McDonald, SS Chavan, ... Blood 128 (22), 4431, 2016 | 9 | 2016 |
High risk multiple myeloma demonstrates marked spatial genomic heterogeneity between focal lesions and random bone marrow; implications for targeted therapy and treatment … N Weinhold, SS Chavan, C Heuck, OW Stephens, R Tytarenko, M Bauer, ... Blood, The Journal of the American Society of Hematology 126 (23), 20-20, 2015 | 8 | 2015 |
Genomic Classification and Individualized Prognosis in Multiple Myeloma F Maura, AR Rajanna, B Ziccheddu, AM Poos, A Derkach, K Maclachlan, ... Journal of Clinical Oncology, JCO. 23.01277, 2024 | 6 | 2024 |
Chimeric antigen receptor T cell therapy pipeline at a glance: a retrospective and systematic analysis from clinicaltrials. Gov EFM Cortes, CK Stein, PAL Diaz, CA Ramirez-Segura, JE Castro Blood 134, 5629, 2019 | 6 | 2019 |