| Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden ZR Chalmers, CF Connelly, D Fabrizio, L Gay, SM Ali, R Ennis, A Schrock, ... Genome medicine 9, 1-14, 2017 | 2909 | 2017 |
| Mutational processes molding the genomes of 21 breast cancers S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ... Cell 149 (5), 979-993, 2012 | 2055 | 2012 |
| A high-resolution recombination map of the human genome A Kong, DF Gudbjartsson, J Sainz, GM Jonsdottir, SA Gudjonsson, ... Nature genetics 31 (3), 241-247, 2002 | 2005 | 2002 |
| Clinical and biological implications of driver mutations in myelodysplastic syndromes E Papaemmanuil, M Gerstung, L Malcovati, S Tauro, G Gundem, ... Blood, The Journal of the American Society of Hematology 122 (22), 3616-3627, 2013 | 1984 | 2013 |
| The life history of 21 breast cancers S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ... Cell 149 (5), 994-1007, 2012 | 1547 | 2012 |
| Somatic SF3B1 Mutation in Myelodysplasia with Ring Sideroblasts E Papaemmanuil, M Cazzola, J Boultwood, L Malcovati, P Vyas, D Bowen, ... New England Journal of Medicine 365 (15), 1384-1395, 2011 | 1421 | 2011 |
| Immune checkpoint inhibition for hypermutant glioblastoma multiforme resulting from germline biallelic mismatch repair deficiency E Bouffet, V Larouche, BB Campbell, D Merico, R De Borja, M Aronson, ... Journal of clinical oncology 34 (19), 2206-2211, 2016 | 828 | 2016 |
| Comprehensive analysis of hypermutation in human cancer BB Campbell, N Light, D Fabrizio, M Zatzman, F Fuligni, R de Borja, ... Cell 171 (5), 1042-1056. e10, 2017 | 689 | 2017 |
| Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes JMC Tubio, Y Li, YS Ju, I Martincorena, SL Cooke, M Tojo, G Gundem, ... Science 345 (6196), 1251343, 2014 | 437 | 2014 |
| Copy number variations and cancer A Shlien, D Malkin Genome medicine 1, 1-9, 2009 | 433 | 2009 |
| Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study A Villani, U Tabori, J Schiffman, A Shlien, J Beyene, H Druker, ... The lancet oncology 12 (6), 559-567, 2011 | 408 | 2011 |
| Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer YS Ju, LB Alexandrov, M Gerstung, I Martincorena, S Nik-Zainal, ... elife 3, e02935, 2014 | 392 | 2014 |
| Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers A Shlien, BB Campbell, R De Borja, LB Alexandrov, D Merico, D Wedge, ... Nature genetics 47 (3), 257-262, 2015 | 368 | 2015 |
| Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer S Nik-Zainal, DC Wedge, LB Alexandrov, M Petljak, AP Butler, N Bolli, ... Nature genetics 46 (5), 487-491, 2014 | 305 | 2014 |
| BRAF Mutation and CDKN2A Deletion Define a Clinically Distinct Subgroup of Childhood Secondary High-Grade Glioma M Mistry, N Zhukova, D Merico, P Rakopoulos, R Krishnatry, M Shago, ... Journal of clinical oncology 33 (9), 1015-1022, 2015 | 286 | 2015 |
| Whole exome sequencing of adenoid cystic carcinoma PJ Stephens, HR Davies, Y Mitani, P Van Loo, A Shlien, PS Tarpey, ... The Journal of clinical investigation 123 (7), 2965-2968, 2013 | 283 | 2013 |
| Mutational signatures of ionizing radiation in second malignancies S Behjati, G Gundem, DC Wedge, ND Roberts, PS Tarpey, SL Cooke, ... Nature communications 7 (1), 1-8, 2016 | 261 | 2016 |
| Excessive genomic DNA copy number variation in the Li–Fraumeni cancer predisposition syndrome A Shlien, U Tabori, CR Marshall, M Pienkowska, L Feuk, A Novokmet, ... Proceedings of the National Academy of Sciences 105 (32), 11264-11269, 2008 | 232 | 2008 |
| Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma S Behjati, PS Tarpey, K Haase, H Ye, MD Young, LB Alexandrov, ... Nature communications 8 (1), 15936, 2017 | 211 | 2017 |
| TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors U Tabori, A Shlien, B Baskin, S Levitt, P Ray, N Alon, C Hawkins, ... Journal of clinical oncology 28 (12), 1995-2001, 2010 | 207 | 2010 |
