Mechanism and inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase AS Murkin, KA Manning, SA Kholodar Bioorganic Chemistry 57, 171-185, 2014 | 46 | 2014 |
Covalent modification and regulation of the nuclear receptor Nurr1 by a dopamine metabolite JM Bruning, Y Wang, F Oltrabella, B Tian, SA Kholodar, H Liu, ... Cell chemical biology 26 (5), 674-685. e6, 2019 | 43 | 2019 |
DXP reductoisomerase: reaction of the substrate in pieces reveals a catalytic role for the nonreacting phosphodianion group SA Kholodar, AS Murkin Biochemistry 52 (13), 2302-2308, 2013 | 24 | 2013 |
The role of phosphate in a multistep enzymatic reaction: reactions of the substrate and intermediate in pieces SA Kholodar, CL Allen, AM Gulick, AS Murkin Journal of the American Chemical Society 137 (7), 2748-2756, 2015 | 22 | 2015 |
Measurement of enzyme isotope effects SA Kholodar, AK Ghosh, A Kohen Methods in Enzymology 596, 43-83, 2017 | 21 | 2017 |
Oligo(2′-O-methylribonucleotides) and their derivatives: III. 5′-Mono- and 5′-bispyrenyl derivatives of oligo(2′-O-methylribonucleotides) and their 3 … DS Novopashina, OS Totskaya, SA Kholodar’, MI Meshchaninova, ... Russian Journal of Bioorganic Chemistry 34, 602-612, 2008 | 19 | 2008 |
Noncovalent intermediate of thymidylate synthase: Fact or fiction? SA Kholodar, A Kohen Journal of the American Chemical Society 138 (26), 8056-8059, 2016 | 17 | 2016 |
Alteration of the Flexible Loop in 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase Boosts Enthalpy-Driven Inhibition by Fosmidomycin SA Kholodar, G Tombline, J Liu, Z Tan, CL Allen, AM Gulick, AS Murkin Biochemistry 53 (21), 3423-3431, 2014 | 13 | 2014 |
Analogs of the dopamine metabolite 5, 6-dihydroxyindole bind directly to and activate the nuclear receptor Nurr1 SA Kholodar, G Lang, WA Cortopassi, Y Iizuka, HS Brah, MP Jacobson, ... ACS chemical biology 16 (7), 1159-1163, 2021 | 11 | 2021 |
Parallel reaction pathways and noncovalent intermediates in thymidylate synthase revealed by experimental and computational tools SA Kholodar, AK Ghosh, K Świderek, V Moliner, A Kohen Proceedings of the National Academy of Sciences 115 (41), 10311-10314, 2018 | 9 | 2018 |
Multipyrene tandem probes for detection of C677T polymorphism in MTHFR gene SA Kholodar, DS Novopashina, MI Meschaninova, AA Lomzov, ... Nucleic Acids Symposium Series 53 (1), 143-144, 2009 | 5 | 2009 |
New eximer-based tandem systems for SNP detection DS Novopashina, MI Meschaninova, SA Kholodar, AA Lomzov, ... Nucleic Acids Symposium Series 52 (1), 229-230, 2008 | 5 | 2008 |
Multipyrene tandem probes for point mutations detection in DNA SA Kholodar, DS Novopashina, MI Meschaninova, AG Venyaminova Journal of Nucleic Acids 2013, 2013 | 4 | 2013 |
Caught in action: X-ray structure of thymidylate synthase with noncovalent intermediate analog SA Kholodar, JS Finer-Moore, K Swiderek, K Arafet, V Moliner, RM Stroud, ... Biochemistry 60 (16), 1243-1247, 2021 | 1 | 2021 |
Isolation and characterization of a novel intermediate of thymidylate synthase: Possibility of a new class of chemotherapeutic drugs targeting thymidylate synthase AK Ghosh, SA Kholodar, A Kohen ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
QM/MM computations and experimental studies reveals an unexpected intermediate in thymidylate synthase catalysis S Kholodar, V Moliner, A Kohen ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017 | | 2017 |
Tandems of pyrene-labeled oligo (2'-O-methylribonucleotides) for SNP detection D Novopashina, M Meschaninova, S Kholodar, A Venyaminova Collection of Czechoslovak Chemical Communications 10, 417-419, 2015 | | 2015 |
The method for synthesis of new bifunctional conjugates of oligonucleotides D Novopashina, S Kholodar, A Venyaminova Collection of Czechoslovak Chemical Communications 12, 413-415, 2015 | | 2015 |
The role of phosphate in a multistep enzymatic reaction SA Kholodar State University of New York at Buffalo, 2015 | | 2015 |