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Chris Langmead
Chris Langmead
Подтвержден адрес электронной почты в домене monash.edu - Главная страница
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Процитировано
Год
Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation
G Lebon, T Warne, PC Edwards, K Bennett, CJ Langmead, AGW Leslie, ...
Nature 474 (7352), 521-525, 2011
10212011
Muscarinic acetylcholine receptors as CNS drug targets
CJ Langmead, J Watson, C Reavill
Pharmacology & therapeutics 117 (2), 232-243, 2008
5082008
Discovery of 1,2,4-Triazine Derivatives as Adenosine A2A Antagonists using Structure Based Drug Design
M Congreve, SP Andrews, AS Doré, K Hollenstein, E Hurrell, ...
Journal of medicinal chemistry 55 (5), 1898-1903, 2012
3702012
Progress in structure based drug design for G protein-coupled receptors
M Congreve, CJ Langmead, JS Mason, FH Marshall
Journal of medicinal chemistry 54 (13), 4283-4311, 2011
2622011
International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands
A Christopoulos, JP Changeux, WA Catterall, D Fabbro, TP Burris, ...
Pharmacological reviews 66 (4), 918-947, 2014
2342014
Characterisation of the binding of [3H]‐SB‐674042, a novel nonpeptide antagonist, to the human orexin‐1 receptor
CJ Langmead, JC Jerman, SJ Brough, C Scott, RA Porter, HJ Herdon
British journal of pharmacology 141 (2), 340-346, 2004
1932004
The properties of thermostabilised G protein-coupled receptors (StaRs) and their use in drug discovery
N Robertson, A Jazayeri, J Errey, A Baig, E Hurrell, A Zhukov, ...
Neuropharmacology 60 (1), 36-44, 2011
1872011
Identification of Novel Adenosine A2A Receptor Antagonists by Virtual Screening
CJ Langmead, SP Andrews, M Congreve, JC Errey, E Hurrell, ...
Journal of medicinal chemistry 55 (5), 1904-1909, 2012
1542012
Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor, vilazodone
ZA Hughes, KR Starr, CJ Langmead, M Hill, GD Bartoszyk, JJ Hagan, ...
European journal of pharmacology 510 (1-2), 49-57, 2005
1542005
Differential GLP-1R binding and activation by peptide and non-peptide agonists
X Zhang, MJ Belousoff, P Zhao, AJ Kooistra, TT Truong, SY Ang, ...
Molecular Cell 80 (3), 485-500. e7, 2020
1412020
Allosteric agonists of 7TM receptors: expanding the pharmacological toolbox
CJ Langmead, A Christopoulos
Trends in pharmacological sciences 27 (9), 475-481, 2006
1412006
Structure-function studies of allosteric agonism at M2 muscarinic acetylcholine receptors
LT May, VA Avlani, CJ Langmead, HJ Herdon, MD Wood, PM Sexton, ...
Molecular pharmacology 72 (2), 463-476, 2007
1332007
G protein–coupled receptors targeting insulin resistance, obesity, and type 2 diabetes mellitus
DM Riddy, P Delerive, RJ Summers, PM Sexton, CJ Langmead
Pharmacological reviews 70 (1), 39-67, 2018
1282018
Probing the molecular mechanism of interaction between 4-n-butyl-1-[4-(2-methylphenyl)-4-oxo-1-butyl]-piperidine (AC-42) and the muscarinic M1 receptor: direct pharmacological …
CJ Langmead, VAH Fry, IT Forbes, CL Branch, A Christopoulos, ...
Molecular pharmacology 69 (1), 236-246, 2006
1252006
Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77‐LH‐28‐1
CJ Langmead, NE Austin, CL Branch, JT Brown, KA Buchanan, ...
British journal of pharmacology 154 (5), 1104-1115, 2008
1242008
New advances in targeting the resolution of inflammation: implications for specialized pro-resolving mediator GPCR drug discovery
J Park, CJ Langmead, DM Riddy
ACS pharmacology & translational science 3 (1), 88-106, 2020
972020
Pharmacology and structure of isolated conformations of the adenosine A2A receptor define ligand efficacy
KA Bennett, B Tehan, G Lebon, CG Tate, M Weir, FH Marshall, ...
Molecular pharmacology 83 (5), 949-958, 2013
852013
Orthosteric and allosteric modes of interaction of novel selective agonists of the M1 muscarinic acetylcholine receptor
VA Avlani, CJ Langmead, E Guida, MD Wood, BG Tehan, HJ Herdon, ...
Molecular pharmacology 78 (1), 94-104, 2010
802010
Neurochemical Changes in LPA1 Receptor Deficient Mice – A Putative Model of Schizophrenia
C Roberts, P Winter, CS Shilliam, ZA Hughes, C Langmead, PR Maycox, ...
Neurochemical research 30, 371-377, 2005
792005
Crystal structure of the M5 muscarinic acetylcholine receptor
Z Vuckovic, PR Gentry, AE Berizzi, K Hirata, S Varghese, G Thompson, ...
Proceedings of the National Academy of Sciences 116 (51), 26001-26007, 2019
782019
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