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Jehad H Edwan
Jehad H Edwan
NIAMS
Verified email at mail.nih.gov
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Year
A role for interleukin-2 trans-presentation in dendritic cell–mediated T cell activation in humans, as revealed by daclizumab therapy
SC Wuest, JH Edwan, JF Martin, S Han, JSA Perry, CM Cartagena, ...
Nature medicine 17 (5), 604-609, 2011
3112011
Flt-3 ligand reverses late allergic response and airway hyper-responsiveness in a mouse model of allergic inflammation
JH Edwan, G Perry, JE Talmadge, DK Agrawal
The Journal of Immunology 172 (8), 5016-5023, 2004
852004
Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors
A Giannelou, H Wang, Q Zhou, YH Park, MS Abu-Asab, K Ylaya, ...
Annals of the rheumatic diseases 77 (4), 612-619, 2018
532018
Novel immunomodulatory oligonucleotides prevent development of allergic airway inflammation and airway hyperresponsiveness in asthma
DK Agrawal, J Edwan, ER Kandimalla, D Yu, L Bhagat, D Wang, ...
International immunopharmacology 4 (1), 127-138, 2004
462004
Flt3-L increases CD4+ CD25+ Foxp3+ ICOS+ cells in the lungs of cockroach-sensitized and-challenged mice
HS McGee, JH Edwan, DK Agrawal
American journal of respiratory cell and molecular biology 42 (3), 331-340, 2010
332010
Treatment with Flt3 ligand plasmid reverses allergic airway inflammation in ovalbumin-sensitized and-challenged mice
JH Edwan, JE Talmadge, DK Agrawal
International immunopharmacology 5 (2), 345-357, 2005
322005
ERAP1 reduces accumulation of aberrant and disulfide-linked forms of HLA-B27 on the cell surface
TM Tran, S Hong, JH Edwan, RA Colbert
Molecular immunology 74, 10-17, 2016
262016
Flt3-ligand plasmid prevents the development of pathophysiological features of chronic asthma in a mouse model
JH Edwan, DK Agrawal
Immunologic research 37, 147-159, 2007
162007
Identification of interleukin‐1β–producing monocytes that are susceptible to pyronecrotic cell death in patients with neonatal‐onset multisystem inflammatory disease
JH Edwan, R Goldbach‐Mansky, RA Colbert
Arthritis & Rheumatology 67 (12), 3286-3297, 2015
152015
A2. 35 TRNT1 missense mutations define a new periodic fever syndrome
AA Giannelou, Q Zhou, M Stoffels, A Ombrello, D Stone, JH Edwan, ...
Annals of the Rheumatic Diseases 74 (Suppl 1), A30-A30, 2015
42015
TRNT1 missense mutations define an autoinflammatory disease characterized by recurrent fever, severe anemia, and B-cell immunodeficiency
I Aksentijevich, Q Zhou, A Giannelou, A Sediva, D Stone, S Rosenzweig, ...
Pediatric Rheumatology 12 (1), 1-2, 2014
32014
Evidence That STAT3 controls NLRP3 inflammasome-dependent Release Of IL-1 beta and Pyronecrosis Through Regulation of mitochondrial activity
JH Edwan, JJ Chae, RT Goldbach-Mansky, RA Colbert
ARTHRITIS AND RHEUMATISM 65, S1170-S1170, 2013
32013
STAT3 Plays a Central Role in NLRP3 Inflammasome-Mediated IL-1 beta Production and Pyronecrosis.
JH Edwan, TM Tran, M Abu-Asab, RT Goldbach-Mansky, RA Colbert
ARTHRITIS AND RHEUMATISM 64 (10), S136-S136, 2012
22012
Treatment of PAS patients with selective PDE-4 inhibitor Rolipram inhibits Th1/Th17 T cell responses, but fails to inhibit brain inflammatory activity
B Bielekova, R Orlowski, T Howard, N Richert, C Chase, J Martin, ...
Neurology 70 (11), A226-A226, 2008
22008
STAT3-Mediated Regulation of Mitochondrial Membrane Potential Is Critical for NLRP3 Inflammasome Activation
JH Edwan, R Goldbach-Mansky, RA Colbert
ARTHRITIS & RHEUMATOLOGY 66, S797-S797, 2014
12014
Therapeutic Effect of Flt3-Ligand in Cockroach Antigen Induced Allergic Airway Inflammation and Airway Hyper-Responsiveness
JH Edwan, DK Agrawal
Journal of Allergy and Clinical Immunology 117 (2), S150, 2006
12006
Regulation of Mitochondrial Proton Gradient Is Critical for NLRP3 Inflammasome Activation
JH Edwan, R Goldbach-Mansky, RA Colbert
ARTHRITIS & RHEUMATOLOGY 68, 2016
2016
Proteostasis Dysregulation and Autoinflammation in Patients with TRNT1 Deficiency
A Giannelou, Q Zhou, H Wang, AA Mones, HW Sun, DL Stone, ...
ARTHRITIS & RHEUMATOLOGY 68, 2016
2016
Events Upstream of Caspase-1 Activation in NLRP3-Mediated Cell Death in NOMID
JH Edwan, R Goldbach-Mansky, RA Colbert
ARTHRITIS & RHEUMATOLOGY 67, 2015
2015
Effect of ERAP1 Knockdown on Conformation of HLA-B27 and Other HLA Class I Molecules in Human Monocytic Cells.
TM Tran, S Hong, JH Edwan, RA Colbert
ARTHRITIS & RHEUMATOLOGY 66, S272-S272, 2014
2014
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