A role for interleukin-2 trans-presentation in dendritic cell–mediated T cell activation in humans, as revealed by daclizumab therapy SC Wuest, JH Edwan, JF Martin, S Han, JSA Perry, CM Cartagena, ... Nature medicine 17 (5), 604-609, 2011 | 311 | 2011 |
Flt-3 ligand reverses late allergic response and airway hyper-responsiveness in a mouse model of allergic inflammation JH Edwan, G Perry, JE Talmadge, DK Agrawal The Journal of Immunology 172 (8), 5016-5023, 2004 | 85 | 2004 |
Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors A Giannelou, H Wang, Q Zhou, YH Park, MS Abu-Asab, K Ylaya, ... Annals of the rheumatic diseases 77 (4), 612-619, 2018 | 53 | 2018 |
Novel immunomodulatory oligonucleotides prevent development of allergic airway inflammation and airway hyperresponsiveness in asthma DK Agrawal, J Edwan, ER Kandimalla, D Yu, L Bhagat, D Wang, ... International immunopharmacology 4 (1), 127-138, 2004 | 46 | 2004 |
Flt3-L increases CD4+ CD25+ Foxp3+ ICOS+ cells in the lungs of cockroach-sensitized and-challenged mice HS McGee, JH Edwan, DK Agrawal American journal of respiratory cell and molecular biology 42 (3), 331-340, 2010 | 33 | 2010 |
Treatment with Flt3 ligand plasmid reverses allergic airway inflammation in ovalbumin-sensitized and-challenged mice JH Edwan, JE Talmadge, DK Agrawal International immunopharmacology 5 (2), 345-357, 2005 | 32 | 2005 |
ERAP1 reduces accumulation of aberrant and disulfide-linked forms of HLA-B27 on the cell surface TM Tran, S Hong, JH Edwan, RA Colbert Molecular immunology 74, 10-17, 2016 | 26 | 2016 |
Flt3-ligand plasmid prevents the development of pathophysiological features of chronic asthma in a mouse model JH Edwan, DK Agrawal Immunologic research 37, 147-159, 2007 | 16 | 2007 |
Identification of interleukin‐1β–producing monocytes that are susceptible to pyronecrotic cell death in patients with neonatal‐onset multisystem inflammatory disease JH Edwan, R Goldbach‐Mansky, RA Colbert Arthritis & Rheumatology 67 (12), 3286-3297, 2015 | 15 | 2015 |
A2. 35 TRNT1 missense mutations define a new periodic fever syndrome AA Giannelou, Q Zhou, M Stoffels, A Ombrello, D Stone, JH Edwan, ... Annals of the Rheumatic Diseases 74 (Suppl 1), A30-A30, 2015 | 4 | 2015 |
TRNT1 missense mutations define an autoinflammatory disease characterized by recurrent fever, severe anemia, and B-cell immunodeficiency I Aksentijevich, Q Zhou, A Giannelou, A Sediva, D Stone, S Rosenzweig, ... Pediatric Rheumatology 12 (1), 1-2, 2014 | 3 | 2014 |
Evidence That STAT3 controls NLRP3 inflammasome-dependent Release Of IL-1 beta and Pyronecrosis Through Regulation of mitochondrial activity JH Edwan, JJ Chae, RT Goldbach-Mansky, RA Colbert ARTHRITIS AND RHEUMATISM 65, S1170-S1170, 2013 | 3 | 2013 |
STAT3 Plays a Central Role in NLRP3 Inflammasome-Mediated IL-1 beta Production and Pyronecrosis. JH Edwan, TM Tran, M Abu-Asab, RT Goldbach-Mansky, RA Colbert ARTHRITIS AND RHEUMATISM 64 (10), S136-S136, 2012 | 2 | 2012 |
Treatment of PAS patients with selective PDE-4 inhibitor Rolipram inhibits Th1/Th17 T cell responses, but fails to inhibit brain inflammatory activity B Bielekova, R Orlowski, T Howard, N Richert, C Chase, J Martin, ... Neurology 70 (11), A226-A226, 2008 | 2 | 2008 |
STAT3-Mediated Regulation of Mitochondrial Membrane Potential Is Critical for NLRP3 Inflammasome Activation JH Edwan, R Goldbach-Mansky, RA Colbert ARTHRITIS & RHEUMATOLOGY 66, S797-S797, 2014 | 1 | 2014 |
Therapeutic Effect of Flt3-Ligand in Cockroach Antigen Induced Allergic Airway Inflammation and Airway Hyper-Responsiveness JH Edwan, DK Agrawal Journal of Allergy and Clinical Immunology 117 (2), S150, 2006 | 1 | 2006 |
Regulation of Mitochondrial Proton Gradient Is Critical for NLRP3 Inflammasome Activation JH Edwan, R Goldbach-Mansky, RA Colbert ARTHRITIS & RHEUMATOLOGY 68, 2016 | | 2016 |
Proteostasis Dysregulation and Autoinflammation in Patients with TRNT1 Deficiency A Giannelou, Q Zhou, H Wang, AA Mones, HW Sun, DL Stone, ... ARTHRITIS & RHEUMATOLOGY 68, 2016 | | 2016 |
Events Upstream of Caspase-1 Activation in NLRP3-Mediated Cell Death in NOMID JH Edwan, R Goldbach-Mansky, RA Colbert ARTHRITIS & RHEUMATOLOGY 67, 2015 | | 2015 |
Effect of ERAP1 Knockdown on Conformation of HLA-B27 and Other HLA Class I Molecules in Human Monocytic Cells. TM Tran, S Hong, JH Edwan, RA Colbert ARTHRITIS & RHEUMATOLOGY 66, S272-S272, 2014 | | 2014 |