The role of PI3K/AKT-related PIP5K1α and the discovery of its selective inhibitor for treatment of advanced prostate cancer J Semenas, A Hedblom, RR Miftakhova, M Sarwar, R Larsson, ... Proceedings of the National Academy of Sciences 111 (35), E3689-E3698, 2014 | 103 | 2014 |
The interplay between AR, EGF receptor and MMP-9 signaling pathways in invasive prostate cancer A Mandel, P Larsson, M Sarwar, J Semenas, AS Syed Khaja, JL Persson Molecular Medicine 24 (1), 1-13, 2018 | 57 | 2018 |
Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells M Sarwar, J Semenas, R Miftakhova, A Simoulis, B Robinson, ... Oncotarget 7 (39), 63065, 2016 | 48 | 2016 |
Protein kinase A (PKA) pathway is functionally linked to androgen receptor (AR) in the progression of prostate cancer M Sarwar, S Sandberg, PA Abrahamsson, JL Persson Urologic Oncology: Seminars and Original Investigations 32 (1), 25. e1-25. e12, 2014 | 41 | 2014 |
The role of PIP5K1α/pAKT and targeted inhibition of growth of subtypes of breast cancer using PIP5K1α inhibitor M Sarwar, AS Syed Khaja, M Aleskandarany, R Karlsson, M Althobiti, ... Oncogene 38 (3), 375-389, 2019 | 39 | 2019 |
The functional interlink between AR and MMP9/VEGF signaling axis is mediated through PIP5K1α/pAKT in prostate cancer P Larsson, AS Syed Khaja, J Semenas, T Wang, M Sarwar, N Dizeyi, ... International journal of cancer 146 (6), 1686-1699, 2020 | 38 | 2020 |
CDK1 interacts with RARγ and plays an important role in treatment response of acute myeloid leukemia A Hedblom, K Laursen, R Miftakhova, M Sarwar, L Anagnostaki, ... Cell Cycle 12 (8), 1251-1266, 2013 | 34 | 2013 |
The protein kinase A (PKA) intracellular pathway and androgen receptor: a novel mechanism underlying the castration-resistant and metastatic prostate cancer M Sarwar, JL Persson J Cancer Sci Ther 5, 003, 2011 | 10 | 2011 |
Establishment of prostate tumor growth and metastasis is supported by bone marrow cells and is mediated by pip5k1α lipid kinase R Karlsson, P Larsson, R Miftakhova, AS Syed Khaja, M Sarwar, ... Cancers 12 (9), 2719, 2020 | 9 | 2020 |
PIP5K1α is required for promoting tumor progression in castration-resistant prostate cancer T Wang, M Sarwar, JB Whitchurch, HM Collins, T Green, J Semenas, A Ali, ... Frontiers in cell and developmental biology 10, 798590, 2022 | 8 | 2022 |
Application of the CRISPR/Cas9 system to identify the role of N-terminal region of PIP5K1α in castration resistant prostate cancer M Sarwar, J Semenas, T Wang, J Persson European Urology 83, S1676, 2023 | | 2023 |
FcγRIIIa receptor interacts with androgen receptor and PIP5K1α to promote growth and metastasis of prostate cancer PF Larsson, R Karlsson, M Sarwar, R Miftakhova, T Wang, AS Syed Khaja, ... Molecular Oncology 16 (13), 2496-2517, 2022 | | 2022 |
PIP5K1? is Required for Promoting Tumor Progression in Castration-Resistant Prostate Cancer T Wang, M Sarwar, JB Whitchurch, HM Collins, T Green, J Semenas, A Ali, ... Frontiers in Cell and Developmental Biology 10, 2022 | | 2022 |
A novel PIP5K1α/AKT pathway is involved in KRAS (G12D) and Trp53-dependent growth of pancreatic tumor T Wang, N Suwannakul, M Sarwar, ASS Khaja, JL Persson | | 2022 |
The role of phosphatidylinositol 4-phosphate 5-kinase type І alpha (PIP5K1α) and utility of its inhibitor for targeting metastatic cancer M Sarwar | | 2018 |
TARGET PI3K/AKT-RELATED LIPID KINASE PATHWAYS FOR TREATMENT OF ADVANCED CANCER J Semenas, A Hedblom, M Sarwar, R Miftakhova, R Larsson, ... ANTICANCER RESEARCH 34 (12), 7481-7481, 2014 | | 2014 |
Functional link between the Protein kinase A (PKA) pathway and androgen receptor (AR) in prostate cancer (PCa) and characterization of the AR directed novel therapeutic compounds M Sarwar | | 2013 |
The Functional Link Between CDK1 and Retinoic Acid Receptor γ (RARγ) in Response to Treatment with All-Trans Retinoic Acid A Hedblom, KB Laursen, RR Miftakhova, M Sarwar, NP Mongan, ... Blood 118 (21), 2485, 2011 | | 2011 |
Establishment of prostate tumor growth and metastasis is supported by bone marrow cells and is mediated by pip5k1α lipid kinase N Ødum, A Simoulis, A Kumar, R Karlsson, K Ekström-Holka, P Larsson, ... | | |
Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells A Simoulis, P Abrahamsson, H Johnsson, B Robinson, N Mongan, ... | | |