| Depletion of human DNA in spiked clinical specimens for improvement of sensitivity of pathogen detection by next-generation sequencing MR Hasan, A Rawat, P Tang, PV Jithesh, E Thomas, R Tan, P Tilley Journal of clinical microbiology 54 (4), 919-927, 2016 | 198 | 2016 |
| The Bethesda handbook of clinical oncology J Abraham, JL Gulley Lippincott Williams & Wilkins, 2022 | 150 | 2022 |
| The epigenetic landscape of oral squamous cell carcinoma PV Jithesh, JM Risk, AG Schache, J Dhanda, B Lane, T Liloglou, RJ Shaw British journal of cancer 108 (2), 370-379, 2013 | 120 | 2013 |
| ADAM17-dependent c-MET-STAT3 signaling mediates resistance to MEK inhibitors in KRAS mutant colorectal cancer S Van Schaeybroeck, M Kalimutho, PD Dunne, R Carson, W Allen, ... Cell reports 7 (6), 1940-1955, 2014 | 110 | 2014 |
| Gene expression meta-analysis identifies VDAC1 as a predictor of poor outcome in early stage non-small cell lung cancer C Grills, PV Jithesh, J Blayney, SD Zhang, DA Fennell PloS one 6 (1), e14635, 2011 | 72 | 2011 |
| Targeting treatment-resistant breast cancer stem cells with FKBPL and its peptide derivative, AD-01, via the CD44 pathway L McClements, A Yakkundi, A Papaspyropoulos, H Harrison, MP Ablett, ... Clinical cancer research 19 (14), 3881-3893, 2013 | 71 | 2013 |
| Transcriptional subtyping and CD8 immunohistochemistry identifies patients with stage II and III colorectal cancer with poor prognosis who benefit from adjuvant chemotherapy WL Allen, PD Dunne, S McDade, E Scanlon, M Loughrey, HG Coleman, ... JCO precision oncology 2, 1-15, 2018 | 66 | 2018 |
| Identification of galanin and its receptor GalR1 as novel determinants of resistance to chemotherapy and potential biomarkers in colorectal cancer L Stevenson, WL Allen, R Turkington, PV Jithesh, I Proutski, G Stewart, ... Clinical cancer research 18 (19), 5412-5426, 2012 | 62 | 2012 |
| Three copies of four interferon receptor genes underlie a mild type I interferonopathy in Down syndrome XF Kong, L Worley, D Rinchai, V Bondet, PV Jithesh, M Goulet, ... Journal of clinical immunology 40, 807-819, 2020 | 48 | 2020 |
| Total Proteome Analysis Identifies Migration Defects as a Major Pathogenetic Factor in Immunoglobulin Heavy Chain Variable Region (IGHV)-unmutated Chronic Lymphocytic Leukemia*[S] GL Eagle, J Zhuang, RE Jenkins, KJ Till, PV Jithesh, K Lin, GG Johnson, ... Molecular & Cellular Proteomics 14 (4), 933-945, 2015 | 46 | 2015 |
| A systems biology approach identifies SART1 as a novel determinant of both 5-fluorouracil and SN38 drug resistance in colorectal cancer WL Allen, L Stevenson, VM Coyle, PV Jithesh, I Proutski, G Carson, ... Molecular cancer therapeutics 11 (1), 119-131, 2012 | 43 | 2012 |
| FKBPL regulates estrogen receptor signaling and determines response to endocrine therapy HD McKeen, C Byrne, PV Jithesh, C Donley, A Valentine, A Yakkundi, ... Cancer research 70 (3), 1090-1100, 2010 | 42 | 2010 |
| Identification of RBCK1 as a novel regulator of FKBPL: implications for tumor growth and response to tamoxifen C Donley, K McClelland, HD McKeen, L Nelson, A Yakkundi, PV Jithesh, ... Oncogene 33 (26), 3441-3450, 2014 | 41 | 2014 |
| Estrogen receptor β activation impairs mitochondrial oxidative metabolism and affects malignant mesothelioma cell growth in vitro and in vivo AG Manente, D Valenti, G Pinton, PV Jithesh, A Daga, L Rossi, SG Gray, ... Oncogenesis 2 (9), e72-e72, 2013 | 41 | 2013 |
| Analysis of gene expression in 3D spheroids highlights a survival role for ASS1 in mesothelioma D Barbone, L Van Dam, C Follo, PV Jithesh, SD Zhang, WG Richards, ... PLoS One 11 (3), e0150044, 2016 | 40 | 2016 |
| Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits G Thareja, Y Al-Sarraj, A Belkadi, M Almotawa, ... Nature Communications 12 (1), 1250, 2021 | 38 | 2021 |
| Qatar genome: Insights on genomics from the Middle East H Mbarek, G Devadoss Gandhi, S Selvaraj, W Al‐Muftah, R Badji, ... Human mutation 43 (4), 499-510, 2022 | 37 | 2022 |
| Ran GTPase promotes cancer progression via Met receptor-mediated downstream signaling HF Yuen, KK Chan, A Platt-Higgins, ELH Dakir, KB Matchett, YA Haggag, ... Oncotarget 7 (46), 75854, 2016 | 31 | 2016 |
| Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk N Shrine, AG Izquierdo, J Chen, R Packer, RJ Hall, AL Guyatt, C Batini, ... Nature genetics 55 (3), 410-422, 2023 | 29 | 2023 |
| AKT1 has dual actions on the glucocorticoid receptor by cooperating with 14-3-3 T Habib, A Sadoun, N Nader, S Suzuki, W Liu, PV Jithesh, T Kino Molecular and cellular endocrinology 439, 431-443, 2017 | 29 | 2017 |
Shane McKeeGenetic Medicine, Belfast City HospitalVerified email at belfasttrust.hscni.net
