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ikbel achour
ikbel achour
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Title
Cited by
Cited by
Year
Single-domain antibodies recognize selectively small oligomeric forms of amyloid β, prevent Aβ-induced neurotoxicity and inhibit fibril formation
P Lafaye, I Achour, P England, C Duyckaerts, F Rougeon
Molecular immunology 46 (4), 695-704, 2009
1272009
Design and Efficacy of a Monovalent Bispecific PD-1/CTLA4 Antibody That Enhances CTLA4 Blockade on PD-1+ Activated T Cells
SJ Dovedi, MJ Elder, C Yang, SI Sitnikova, L Irving, A Hansen, J Hair, ...
Cancer Discovery 11 (5), 1100-1117, 2021
982021
Tetrameric and homodimeric camelid IgGs originate from the same IgH locus
I Achour, P Cavelier, M Tichit, C Bouchier, P Lafaye, F Rougeon
The journal of immunology 181 (3), 2001-2009, 2008
972008
Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform
A Klarenbeek, KE Mazouari, A Desmyter, C Blanchetot, A Hultberg, ...
MAbs 7 (4), 693-706, 2015
782015
The discriminatory cost of ICD-10-CM transition between clinical specialties: metrics, case study, and mitigating tools
AD Boyd, JJ Li, MD Burton, M Jonen, V Gardeux, I Achour, RQ Luo, ...
Journal of the American Medical Informatics Association 20 (4), 708-717, 2013
572013
Network models of genome-wide association studies uncover the topological centrality of protein interactions in complex diseases
Y Lee, H Li, J Li, E Rebman, I Achour, KE Regan, ER Gamazon, JL Chen, ...
Journal of the American Medical Informatics Association, 2013
552013
Flexible ordering of antibody class switch and V(D)J joining during B-cell ontogeny
S Kumar, R Wuerffel, I Achour, B Lajoie, R Sen, J Dekker, AJ Feeney, ...
502013
Three‐dimensional architecture of the IgH locus facilitates class switch recombination
AL Kenter, S Feldman, R Wuerffel, I Achour, L Wang, S Kumar
Annals of the New York Academy of Sciences 1267 (1), 86-94, 2012
472012
‘N-of-1-pathways’ unveils personal deregulated mechanisms from a single pair of RNA-Seq samples: towards precision medicine
V Gardeux, I Achour, J Li, M Maienschein-Cline, H Li, L Pesce, ...
Journal of the American Medical Informatics Association 21 (6), 1015-1025, 2014
422014
hMSH2 expression is driven by AP1‐dependent regulation through phorbol‐ester exposure
O Humbert, I Achour, D Lautier, G Laurent, B Salles
Nucleic acids research 31 (19), 5627-5634, 2003
322003
53BP1 contributes to Igh locus chromatin topology during class switch recombination
S Feldman, R Wuerffel, I Achour, L Wang, PB Carpenter, AL Kenter
The Journal of Immunology 198 (6), 2434-2444, 2017
312017
A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbations
V Gardeux, J Berghout, I Achour, AG Schissler, Q Li, C Kenost, J Li, ...
Journal of the American Medical Informatics Association 24 (6), 1116-1126, 2017
282017
N-of-1-pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes
Q Li, AG Schissler, V Gardeux, I Achour, C Kenost, J Berghout, H Li, ...
BMC Medical Genomics 10, 5-16, 2017
282017
Integrative genomics analyses unveil downstream biological effectors of disease-specific polymorphisms buried in intergenic regions
H Li, I Achour, L Bastarache, J Berghout, V Gardeux, J Li, Y Lee, L Pesce, ...
NPJ genomic medicine 1 (1), 1-12, 2016
272016
Dynamic changes of RNA-sequencing expression for precision medicine: N-of-1-pathways Mahalanobis distance within pathways of single subjects predicts breast cancer survival
AG Schissler, V Gardeux, Q Li, I Achour, H Li, WW Piegorsch, YA Lussier
Bioinformatics 31 (12), i293-i302, 2015
272015
Constraints Contributed by Chromatin Looping Limit Recombination Targeting during Immunoglobulin Class Switch Recombination.
KAL Feldman S, Achour I, Wuerffel R, Kumar S, Gerasimova T, Sen R
Journal of Immunology, 2015
25*2015
Anti-PD-1 monoclonal antibody MEDI0680 in a phase I study of patients with advanced solid malignancies
A Naing, J Infante, S Goel, H Burris, C Black, S Marshall, I Achour, ...
Journal for immunotherapy of cancer 7, 1-15, 2019
212019
kMEn: Analyzing noisy and bidirectional transcriptional pathway responses in single subjects
Q Li, AG Schissler, V Gardeux, J Berghout, I Achour, C Kenost, H Li, ...
Journal of biomedical informatics 66, 32-41, 2017
202017
Concordance of deregulated mechanisms unveiled in underpowered experiments: PTBP1 knockdown case study
V Gardeux, AD Arslan, I Achour, TT Ho, WT Beck, YA Lussier
BMC medical genomics 7, 1-13, 2014
202014
MEDI5752: A novel bispecific antibody that preferentially targets CTLA-4 on PD-1 expressing T-cells
SJ Dovedi, Y Mazor, M Elder, S Hasani, B Wang, S Mosely, D Jones, ...
Cancer Research 78 (13_Supplement), 2776-2776, 2018
172018
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