| High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire BJ DeKosky, GC Ippolito, RP Deschner, JJ Lavinder, Y Wine, ... Nature biotechnology 31 (2), 166-169, 2013 | 516 | 2013 |
| Engineering of protease variants exhibiting high catalytic activity and exquisite substrate selectivity N Varadarajan, J Gam, MJ Olsen, G Georgiou, BL Iverson Proceedings of the National Academy of Sciences 102 (19), 6855-6860, 2005 | 203 | 2005 |
| Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells M Daher, R Basar, E Gokdemir, N Baran, N Uprety, AK Nunez Cortes, ... Blood, The Journal of the American Society of Hematology 137 (5), 624-636, 2021 | 177 | 2021 |
| A high-throughput single-cell analysis of human CD8+ T cell functions reveals discordance for cytokine secretion and cytolysis N Varadarajan, B Julg, YJ Yamanaka, H Chen, AO Ogunniyi, E McAndrew, ... The Journal of clinical investigation 121 (11), 2011 | 172 | 2011 |
| CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression K Fousek, J Watanabe, SK Joseph, A George, X An, TT Byrd, JS Morris, ... Leukemia 35 (1), 75-89, 2021 | 137 | 2021 |
| IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions CH Lee, G Romain, W Yan, M Watanabe, W Charab, B Todorova, J Lee, ... Nature immunology 18 (8), 889-898, 2017 | 135 | 2017 |
| Highly active and selective endopeptidases with programmed substrate specificities N Varadarajan, S Rodriguez, BY Hwang, G Georgiou, BL Iverson Nature chemical biology 4 (5), 290-294, 2008 | 120 | 2008 |
| Antibody Fc engineering improves frequency and promotes kinetic boosting of serial killing mediated by NK cells G Romain, V Senyukov, N Rey-Villamizar, A Merouane, W Kelton, I Liadi, ... Blood, The Journal of the American Society of Hematology 124 (22), 3241-3249, 2014 | 119 | 2014 |
| Rapid, efficient functional characterization and recovery of HIV-specific human CD8+ T cells using microengraving N Varadarajan, DS Kwon, KM Law, AO Ogunniyi, MN Anahtar, JM Richter, ... Proceedings of the National Academy of Sciences 109 (10), 3885-3890, 2012 | 106* | 2012 |
| Individual Motile CD4+ T Cells Can Participate in Efficient Multikilling through Conjugation to Multiple Tumor Cells I Liadi, H Singh, G Romain, N Rey-Villamizar, A Merouane, ... Cancer immunology research 3 (5), 473-482, 2015 | 104 | 2015 |
| A microfluidic assay for the quantification of the metastatic propensity of breast cancer specimens CL Yankaskas, KN Thompson, CD Paul, MI Vitolo, P Mistriotis, ... Nature biomedical engineering 3 (6), 452-465, 2019 | 100 | 2019 |
| Targeting the interplay between epithelial-to-mesenchymal-transition and the immune system for effective immunotherapy R Soundararajan, JJ Fradette, JM Konen, S Moulder, X Zhang, ... Cancers 11 (5), 714, 2019 | 91 | 2019 |
| Substrate Specificity of the Escherichia coli Outer Membrane Protease OmpP BY Hwang, N Varadarajan, H Li, S Rodriguez, BL Iverson, G Georgiou Journal of bacteriology 189 (2), 522-530, 2007 | 72 | 2007 |
| Single-dose intranasal vaccination elicits systemic and mucosal immunity against SARS-CoV-2 X An, M Martinez-Paniagua, A Rezvan, SR Sefat, M Fathi, S Singh, ... Iscience 24 (9), 2021 | 70 | 2021 |
| Automated profiling of individual cell–cell interactions from high-throughput time-lapse imaging microscopy in nanowell grids (TIMING) A Merouane, N Rey-Villamizar, Y Lu, I Liadi, G Romain, J Lu, H Singh, ... Bioinformatics 31 (19), 3189-3197, 2015 | 61 | 2015 |
| Automated classification of apoptosis in phase contrast microscopy using capsule network A Mobiny, H Lu, HV Nguyen, B Roysam, N Varadarajan IEEE transactions on medical imaging 39 (1), 1-10, 2019 | 58 | 2019 |
| Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter K Ritthipichai, CL Haymaker, M Martinez, A Aschenbrenner, X Yi, ... Clinical Cancer Research 23 (20), 6151-6164, 2017 | 58 | 2017 |
| KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape Y Li, R Basar, G Wang, E Liu, JS Moyes, L Li, LN Kerbauy, N Uprety, ... Nature medicine 28 (10), 2133-2144, 2022 | 54 | 2022 |
| Single-cell profiling of dynamic cytokine secretion and the phenotype of immune cells X An, VG Sendra, I Liadi, B Ramesh, G Romain, C Haymaker, ... PLoS One 12 (8), e0181904, 2017 | 47 | 2017 |
| Mesoscopic protein-rich clusters host the nucleation of mutant p53 amyloid fibrils DS Yang, A Saeedi, A Davtyan, M Fathi, MB Sherman, MS Safari, ... Proceedings of the National Academy of Sciences 118 (10), e2015618118, 2021 | 40 | 2021 |
