Giovanni Stracquadanio
Giovanni Stracquadanio
Personal Chair in Engineering Biology, The University of Edinburgh
Verified email at - Homepage
Cited by
Cited by
Total synthesis of a functional designer eukaryotic chromosome
N Annaluru, H Muller, LA Mitchell, S Ramalingam, G Stracquadanio, ...
science 344 (6179), 55-58, 2014
Design of a synthetic yeast genome
SM Richardson, LA Mitchell, G Stracquadanio, K Yang, JS Dymond, ...
Science 355 (6329), 1040-1044, 2017
“Perfect” designer chromosome V and behavior of a ring derivative
ZX Xie, BZ Li, LA Mitchell, Y Wu, X Qi, Z Jin, B Jia, X Wang, BX Zeng, ...
Science 355 (6329), eaaf4704, 2017
Bug mapping and fitness testing of chemically synthesized chromosome X
Y Wu, BZ Li, M Zhao, LA Mitchell, ZX Xie, QH Lin, X Wang, WH Xiao, ...
Science 355 (6329), eaaf4706, 2017
Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond
LA Mitchell, A Wang, G Stracquadanio, Z Kuang, X Wang, K Yang, ...
Science 355 (6329), eaaf4831, 2017
Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome
Y Shen, Y Wang, T Chen, F Gao, J Gong, D Abramczyk, R Walker, H Zhao, ...
Science 355 (6329), eaaf4791, 2017
The importance of p53 pathway genetics in inherited and somatic cancer genomes
G Stracquadanio, X Wang, M Wallace, A Grawenda, P Zhang, J Hewitt, ...
Nature Reviews Cancer 16 (4), 251--265, 2016
SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes
Y Shen, G Stracquadanio, Y Wang, K Yang, LA Mitchell, Y Xue, Y Cai, ...
Genome research 26 (1), 36-49, 2016
Yeast Golden Gate (yGG) for the Efficient Assembly of S. cerevisiae Transcription Units
N Agmon, LA Mitchell, Y Cai, S Ikushima, J Chuang, A Zheng, WJ Choi, ...
ACS synthetic biology 4 (7), 853-859, 2015
Intrinsic biocontainment: multiplex genome safeguards combine transcriptional and recombinational control of essential yeast genes
Y Cai, N Agmon, WJ Choi, A Ubide, G Stracquadanio, K Caravelli, H Hao, ...
Proceedings of the National Academy of Sciences 112 (6), 1803-1808, 2015
Technological challenges and milestones for writing genomes
N Ostrov, J Beal, T Ellis, DB Gordon, BJ Karas, HH Lee, SC Lenaghan, ...
Science 366 (6463), 310-312, 2019
Generalized pattern search algorithm for peptide structure prediction
G Nicosia, G Stracquadanio
Biophysical journal 95 (10), 4988-4999, 2008
RADOM, an Efficient In Vivo Method for Assembling Designed DNA Fragments up to 10 kb Long in Saccharomyces cerevisiae
Q Lin, B Jia, LA Mitchell, J Luo, K Yang, KI Zeller, W Zhang, Z Xu, ...
ACS synthetic biology 4 (3), 213-220, 2015
Germline and somatic genetic variants in the p53 pathway interact to affect cancer risk, progression, and drug response
P Zhang, I Kitchen-Smith, L Xiong, G Stracquadanio, K Brown, PH Richter, ...
Cancer research 81 (7), 1667-1680, 2021
Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions
Y Zhao, C Coelho, AL Hughes, L Lazar-Stefanita, S Yang, AN Brooks, ...
Cell 186 (24), 5220-5236. e16, 2023
An advanced clonal selection algorithm with ad-hoc network-based hypermutation operators for synthesis of topology and sizing of analog electrical circuits
A Ciccazzo, P Conca, G Nicosia, G Stracquadanio
Artificial Immune Systems: 7th International Conference, ICARIS 2008, Phuket …, 2008
Low escape-rate genome safeguards with minimal molecular perturbation of Saccharomyces cerevisiae
N Agmon, Z Tang, K Yang, B Sutter, S Ikushima, Y Cai, K Caravelli, ...
Proceedings of the National Academy of Sciences 114 (8), E1470-E1479, 2017
Design of robust space trajectories
G Stracquadanio, A La Ferla, M De Felice, G Nicosia
International Conference on Innovative Techniques and Applications of …, 2011
Computational energy-based redesign of robust proteins
G Stracquadanio, G Nicosia
Computers & chemical engineering 35 (3), 464-473, 2011
Analysis and optimization of c3 photosynthetic carbon metabolism
G Stracquadanio, R Umeton, A Papini, P Lio, G Nicosia
2010 IEEE International Conference on BioInformatics and BioEngineering, 44-51, 2010
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