Kivanc Birsoy
Kivanc Birsoy
Chapman-Perelman Assistant Professor, Rockefeller University
Подтвержден адрес электронной почты в домене rockefeller.edu - Главная страница
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer
R Possemato, KM Marks, YD Shaul, ME Pacold, D Kim, K Birsoy, ...
Nature 476 (7360), 346-350, 2011
Identification and characterization of essential genes in the human genome
T Wang, K Birsoy, NW Hughes, KM Krupczak, Y Post, JJ Wei, ES Lander, ...
Science 350 (6264), 1096-1101, 2015
An essential role of the mitochondrial electron transport chain in cell proliferation is to enable aspartate synthesis
K Birsoy, T Wang, WW Chen, E Freinkman, M Abu-Remaileh, DM Sabatini
Cell 162 (3), 540-551, 2015
Identification of white adipocyte progenitor cells in vivo
MS Rodeheffer, K Birsoy, JM Friedman
Cell 135 (2), 240-249, 2008
Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides
K Birsoy, R Possemato, FK Lorbeer, EC Bayraktar, P Thiru, B Yucel, ...
Nature 508 (7494), 108-112, 2014
mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake
ÖH Yilmaz, P Katajisto, DW Lamming, Y Gültekin, KE Bauer-Rowe, ...
Nature 486 (7404), 490-495, 2012
A Diverse Array of Cancer-Associated MTOR Mutations Are Hyperactivating and Can Predict Rapamycin SensitivityCancer-Associated Hyperactivating MTOR Mutations
BC Grabiner, V Nardi, K Birsoy, R Possemato, K Shen, S Sinha, A Jordan, ...
Cancer discovery 4 (5), 554-563, 2014
NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis
SW Alvarez, VO Sviderskiy, EM Terzi, T Papagiannakopoulos, AL Moreira, ...
Nature 551 (7682), 639-643, 2017
A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate
ME Pacold, KR Brimacombe, SH Chan, JM Rohde, CA Lewis, ...
Nature chemical biology 12 (6), 452-458, 2016
Transcriptional regulation of adipogenesis by KLF4
K Birsoy, Z Chen, J Friedman
Cell metabolism 7 (4), 339-347, 2008
Absolute quantification of matrix metabolites reveals the dynamics of mitochondrial metabolism
WW Chen, E Freinkman, T Wang, K Birsoy, DM Sabatini
Cell 166 (5), 1324-1337. e11, 2016
SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance
D Kim, BP Fiske, K Birsoy, E Freinkman, K Kami, RL Possemato, ...
Nature 520 (7547), 363-367, 2015
Antidiabetic effects of IGFBP2, a leptin-regulated gene
K Hedbacker, K Birsoy, RW Wysocki, E Asilmaz, RS Ahima, IS Farooqi, ...
Cell metabolism 11 (1), 11-22, 2010
Molecular Profiling of Activated Neurons by Phosphorylated Ribosome Capture
ZA Knight, K Tan, K Birsoy, S Schmidt, JL Garrison, RW Wysocki, ...
Cell 151 (5), 1126-1137, 2012
Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours
J Garcia-Bermudez, L Baudrier, K La, XG Zhu, J Fidelin, VO Sviderskiy, ...
Nature cell biology 20 (7), 775-781, 2018
MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors
K Birsoy, T Wang, R Possemato, OH Yilmaz, CE Koch, WW Chen, ...
Nature Genetics, 2013
Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death
J Garcia-Bermudez, L Baudrier, EC Bayraktar, Y Shen, K La, ...
Nature 567 (7746), 118-122, 2019
Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP ProteinsAdipocyte-Derived Lipids Drive Melanoma Progression via FATP
M Zhang, JS Di Martino, RL Bowman, NR Campbell, SC Baksh, ...
Cancer discovery 8 (8), 1006-1025, 2018
Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers
M Soula, RA Weber, O Zilka, H Alwaseem, K La, F Yen, H Molina, ...
Nature chemical biology 16 (12), 1351-1360, 2020
Molecular characterization and clinical relevance of metabolic expression subtypes in human cancers
X Peng, Z Chen, F Farshidfar, X Xu, PL Lorenzi, Y Wang, F Cheng, L Tan, ...
Cell reports 23 (1), 255-269. e4, 2018
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Статьи 1–20